1 research outputs found
Candidiasis, A Rare Cause of Gastric Perforation: A Case Report and Review of Literature
Fungi are unusually rare causes of gastric perforation, with most cases of gastric perforation
occurring as complications of peptic ulcer disease (PUD), nonsteroidal anti‑inflammatory
drugs (NSAIDs) and gastric neoplasms. Here, we report the case of a 70‑year‑old Nigerian
male who presented with severe epigastric pain, with no associated history of PUD,
NSAIDs use or gastric neoplasm. An emergency exploratory laparotomy was performed
and a gastric perforation was discovered and repaired. Histopathological examination
of the gastric perforation edge biopsy revealed an intense Candida growth consisting of
numerous fungal spores and hyphae invading and destroying the gastric wall. He was
subsequently treated with fluconazole antifungal and discharged home after an uneventful
postoperative period