44 research outputs found

    RHIC polarimetry

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    Polarimeters were developed to measure the polarization of the proton beam at RHIC in relative scale through the asymmetry measurement of the elastic proton-carbon scattering. Recoil carbon ions with kinetic energy of 400 ≤ E ≤ 900 keV were detected by silicon strip detectors installed at 90° with respect to the beam. The absolute polarization is given by normalizing against another polarimeter implemented at RHIC, namely a polarized hydrogen gas jet polarimeter. In this report, the details of polarization measurements, data analysis, and systematic uncertainties are discussed based on the data taken during ∫s = 200 GeV operation of Run 05 at RHIC

    Novel Structure Function for Photon Fragmentation into a Λ\Lambda Hyperon and Transverse Λ\Lambda Polarization in Unpolarized Electron-Positron Annihilation

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    The possibility is examined for the inclusive Λ\Lambda in unpolarized electron-positron annihilation to be transversely polarized. Due to final-state interactions, there exists a novel structure function F^(z,Q2)\hat F(z,Q^2) for the inclusive Λ\Lambda hyperon (or any other baryons) production from the unpolarized time-like photon fragmentation, which makes contribution to the transverse Λ\Lambda polarization in the unpolarized electron-positron annihilation.Comment: RevTex, 4 pages, the version appearing in Phys. Rev.

    Latanoprost treatment for open angle glaucoma. The United Kingdom Glaucoma Treatment Study: a multicentre, randomised, placebo-controlled clinical trial

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    BACKGROUND: Treatment of open-angle glaucoma (OAG) aims to prevent vision loss by lowering intraocular pressure (IOP), yet there has been no previous placebo-controlled medical treatment trial assessing vision function preservation. Observation periods in previous (unmasked) trials assessing visual function have typically been at least 5 years. The aim of this study was to assess vision preservation by latanoprost treatment compared to placebo. METHODS In this randomised, triple-masked, placebo-controlled trial, patients with newly-diagnosed OAG were enrolled at 10 UK centres (tertiary referral centres, teaching hospitals, and district general hospitals) between Feb 2007 and Mar 2010. Eligible patients were randomly allocated (1:1) to receive either latanoprost 0·005% or placebo eye drops, provided in identical bottles, once daily to both eyes. Randomization was in permuted blocks stratified by participating centre. The primary hypothesis was that latanoprost treatment reduces incident visual field (VF) deterioration, compared with placebo, by 50% over 2 years. The primary outcome was VF deterioration: 3 locations in the Pattern Deviation Glaucoma Change Probability maps worse than baseline in 2 consecutive VFs, present in 2 consecutive VF pairs. The primary analysis was VF survival in the intention-to-treat population. The trial was terminated in July 2011 on the recommendation of the independent data monitoring committee following an interim analysis. Trial registration number: ISRCTN96423140. FINDINGS: 516 patients were randomised and data on all subjects with post-allocation data (461) were analysed. 18 serious adverse events were reported, none attributable to the study drug. Baseline mean (SD) IOP was 19·6 (4·6) mmHg and 20·1 (4·8) mmHg, and IOP reduction at 24 months 3·8 (4·0) mmHg and 0·9 (3·8) mmHg, in the latanoprost and placebo groups, respectively. Incident VF deterioration (95% CI) by 24 months was 15·0% (10·8, 20·0) in the latanoprost group and 24·8% (19·5, 30·7) in the placebo group (P=0·007). VF survival was significantly longer in the latanoprost group: at 24 months, adjusted hazard ratio (HR) 0·44 (0·28, 0·69) (P=0·0003). The difference between treatment groups was evident after only 12 months, HR 0·47 (0·23, 0·95) (P=0·035). INTERPRETATION: This is the first placebo-controlled trial to demonstrate VF preservation with an IOP-lowering agent in OAG. The study design enabled a relatively short observation period. FUNDING: Pfizer Inc.; UK National Institute for Health Research Biomedical Research Centre
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