11 research outputs found
Research priorities in pediatric parenteral nutrition: a consensus and perspective from ESPGHAN/ESPEN/ESPR/CSPEN
We acknowledge all the authors of the ESPGHAN/ESPR/ESPEN/CSPEN pediatric
parenteral nutrition guidelines for their contributions and vote (Christian Braegger,
University Children’s Hospital, Zurich, Switzerland; Jiri Bronsky, University Hospital
Motol, Prague, Czech Republic; Cristina Campoy, Department of Paediatrics, School of
Medicine, University of Granada, Granada, Spain; Magnus Domellof, Department of
Clinical Sciences, Pediatrics, UmeĂĄ University, Sweden; Nicholas Embleton, Newcastle
University, Newcastle upon Tyne, UK; Mary Fewtrell, UCL Great Ormond Street
Institute of Child Health, London, UK; Natasa Fidler, University Medical Centre
Ljubljana, Ljubljana, Slovenia; Axel Franz, University Children’s Hospital, Tuebingen,
Germany; Oliver Goulet, University Sordonne-Paris-Cite; Paris-Descartes Medical
School, Paris, France; Corina Hartmann, Schneider Children’s Medical Center of Israel,
Petach Tikva, Israel and Carmel Medical Center, Israel; Susan Hill, Great Ormond Street
Hospital for Children, NHS Foundation Trust and UCL Institute of Child Health,
London, UK; Iva Hojsak, Children’s Hospital Zagreb, University of Zagreb School of
Medicine, University of J. J. Strossmayer School of Medicine Osijek, Croatia; Sylvia
Iacobelli, CHU La Reunion, Saint Pierre, France; Frank Jochum, Ev. Waldkrankenhaus
Spandau, Berlin, Germany; Koen Joosten, Department of Pediatrics and Pediatric
Surgery, Intensive Care, Erasmus MC Sophia Children’s Hospital, Rotterdam, The
Netherlands; Sanja Kolacek, Children’s Hospital, University of Zagreb School of
Medicine, Zagreb, Croatia; Alexandre Lapillone, Paris-Descartes University, Paris,
France; Szimonetta Lohner, Department of Pediatrics, University of Pecs, Pecs,
Hungary; Dieter Mesotten, KU Leuven, Leuven, Belgium; Walter Mihatsch, Ulm
University, Ulm, and Helios Hospital, Pforzheim, Germany; Francis Mimouni,
Department of Pediatrics, Division of Neonatology, The Wilf Children’s Hospital, the
Shaare Zedek Medical Center, Jerusalem, and the Tel Aviv University, Tel Aviv, Israel;
Christian Molgaard, Department of Nutrition, Exercise and Sports, University of
Copenhagen, and Paediatric Nutrition Unit, Rigshospitalet, Copenhagen, Denmark;
Sissel Moltu, Oslo University Hospital, Oslo, Norway; Antonia Nomayo, Ev.
Waldkrankenhaus Spandau, Berlin, Germany; John Puntis, The General Infirmary at
Leeds, Leeds, UK; Arieh Riskin, Bnai Zion Medical Center, Rappaport Faculty of
Medicine, Technion, Haifa, Israel; Miguel Saenz de Pipaon, Department of
Neonatology, La Paz University Hospital, Red de Salud Materno Infantil y Desarrollo
e SAMID, Universidad Autonoma de Madrid, Madrid, Spain; Raanan Shamir, Schneider
Children’s Medical Center of Israel, Petach Tikva, Israel; Tel Aviv University, Tel Aviv,
Israel; Peter Szitanyi, General University Hospital, First Faculty of Medicine, Charles
University in Prague, Czech Republic; Merit Tabbers, Emma Children’s Hospital,
Amsterdam UMC, Amsterdam, The Netherlands; Chris van den Akker, Emma
Children’s Hospital, Amsterdam UMC, Amsterdam, The Netherlands; Hans van
Goudoever, Emma Children’s Hospital, Amsterdam UMC, Amsterdam, The Netherlands;
Sacha Verbruggen, Department of Pediatrics and Pediatric Surgery, Intensive
Care, Erasmus MC-Sophia Children’s Hospital, Rotterdam, The Netherlands; Cai Wei,
Shanghai Jiao Tong University, Shanghai, China; Weihui Yan, Department of
Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao
Tong University, Shanghai, China) and the members of the ESPR Section on Nutrition,
Gastroenterology and Metabolism (Fredrik Ahlsson, Uppsala University Children’s
Hospital and Department of Women’s and Children’s Health, Uppsala University,
Uppsala, Sweden; Sertac Arslanoglu, Division of Neonatology, Department of
Pediatrics, Istanbul Medeniyet University, Istanbul, Turkey; Wolfgang Bernhard,
Department of Neonatology, Children’s Hospital, Faculty of Medicine, Eberhard-Karls-
University, TĂĽbingen, Germany; Janet Berrington, Newcastle Neonatal Service,
Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK;
Signe Bruun, Hans Christian Andersen Hospital for Children and Adolescents, Odense
University Hospital, Odense, Denmark; Christoph Fusch, Department of Pediatrics, Paracelsus Medical School, General Hospital of Nuremberg, Nuremberg, Germany;
Shalabh Garg, South Tees Hospitals, Middlesborough, UK; Maria Gianni, Department
of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Ann
Hellstrom, Institute of Neuroscience and Physiology, Sahlgrenska Academy at
University of Gothenburg, Gothenburg, Sweden; Claus Klingenberg, Department of
Pediatrics and Adolescence Medicine, University Hospital of North Norway, Tromsø,
Norway; Helen Mactier, Neonatal Unit, Princess Royal Maternity Hospital, Glasgow,
UK; Neena Modi, Section of Neonatal Medicine, Department of Medicine, Chelsea and
Westminster Campus, Imperial College London, London, UK; Niels Rochow, Division
of Neonatology, Department of Pediatrics, McMaster University, Hamilton, Ontario,
Canada; Paola Rogerro, Department of Clinical Sciences and Community Health,
University of Milan, Milan, Italy; Umberto Simeoni, Division of Pediatrics, CHUV &
University of Lausanne, Lausanne, Switzerland; Atul Singhal, Paediatric Nutrition, UCL
Great Ormond Street Institute of Child Health, London, UK.; Ulrich Thome,
Department of Neonatology, Universitatsklinikum Leipzig, Leipzig, Germany; Anne
Twomey, Department of Neonatology, The National Maternity Hospital, Dublin,
Ireland; Mireille Vanpee, Karolinska University Hospital, Stockholm, Sweden; Gitte
Zachariassen, Hans Christian Andersen Hospital for Children and Adolescents,
Odense University Hospital, Odense, Denmark) for their vote.Parenteral nutrition is used to treat children that cannot be fully fed by the enteral route. While the revised ESPGHAN/
ESPEN/ESPR/CSPEN pediatric parenteral nutrition guidelines provide clear guidance on the use of parenteral nutrition in neonates,
infants, and children based on current available evidence, they have helped to crystallize areas where research is lacking or more
studies are needed in order to refine recommendations. This paper collates and discusses the research gaps identified by the
authors of each section of the guidelines and considers each nutrient or group of nutrients in turn, together with aspects around
delivery and organization. The 99 research priorities identified were then ranked in order of importance by clinicians and
researchers working in the field using a survey methodology. The highest ranked priority was the need to understand the
relationship between total energy intake, rapid catch-up growth, later metabolic function, and neurocognitive outcomes. Research
into the optimal intakes of macronutrients needed in order to achieve optimal outcomes also featured prominently. Identifying
research priorities in PN should enable research to be focussed on addressing key issues. Multicentre trials, better definition of
exposure and outcome variables, and long-term metabolic and developmental follow-up will be key to achieving this
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Organisational aspects
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Standard versus individualized parenteral nutrition
ESPGHAN/ESPEN/ESPR guidelines on pediatric parenteral nutrition: Standard versus individualized parenteral nutrition
International audienc
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Fluid and electrolytes
ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Calcium, phosphorus and magnesium.
International audienc