Prevalence of Thrombophilic Mutations in Ischemic Stroke Patients in Isparta, Turkey

Objective: The present study aimed to investigate whether the frequency of factor V, methylenetetrahydrofolate reductase (MTHFR), prothrombin, beta-fibrinogen gene mutations, and human platelet alloantigens (HPA), plasminogen activator inhibitor 1 (PAI1), apolipoprotein E (APOE), and angiotensin converting enzyme (ACE) gene polymorphisms in stroke patients is higher than that in normal individuals

Kanserli Yaşlıda Anoreksi-Kaşeksi Sendromu ve Tedavisi

Weight loss occurs in 30-80% of cancer patients. Weight loss depends on the cancer type, the effected organ-tissue, size and cell turnover. Weight loss is more aggressive in gastric and pancreatic cancers. Patients frequently admit in higher stages of the diasease with severe weight loss. Lung, prostate and colon cancer follow them according to prevalance of cachexia. Proteolysis inducing factor and inflammatory cytokines cause proteolysis and increased energy expenditure due to hypercathabolic situation. Ghrelin receptor resistance causes anorexia. Localization of the tumour, surrounding tissue damage and adverse effects of the treatment procedures can also cause anorexia and weight loss. Weight loss, especially decreased lean body mass, influences the success of the treatment, increases the morbidity and mortality. A significant number of the patients die because of malnutrition and associated adverse events like infection, instead of the diasease itself. Then, early nutrition assessment after the diagnosis is essential with regular visits during the follow-up. When diagnosed, malnutrition or malnutrition risk must be treated immediatel