Papillon Lefevre syndrome: treatment of two cases with a clinical microbiological and histopathological investigation

Papillon Lefevre syndrome is presented in the cases of two female patients of the ages of 7 and 9, who exhibited all typical symptoms of the disease. Microbiological and histopathological studies were done and treatment provided. Actinobacillus actinomycetemcomitans, which is suspected as a pathogenic factor in the disease was identified as well as some other gram negative microorganisms and an antibiogram was performed in which amoxycillin plus clavulanic acid was most effective. Histopathological investigation also confirmed the presence of gram negative bacteria. Granular cell infiltration was predominant in the surface epithelium. Prosthetic appliances were provided for the patients after mechanical and chemical plaque control. In addition to this, antibiotics (amoxycillin plus clavulanic acid) were prescribed every six months. No tooth loss was observed in both patients after more than two years follow-up period. At the moment only one patient is under review and because she is uncooperative, mild periodontal inflammation is still present around the teeth which erupted before the antibiotic regime, but not in the other teeth.</p

Effects of Glass Fiber Layering on the Flexural Strength of Microfill and Hybrid Composites

WOS: 000266599100008PubMed ID: 19508260In stress-bearing cavities, low fracture resistance adversely affects the longevity of the dental resin composite restorations. The aim of this in vitro study was to investigate the effect of glass fiber layering on the flexural strength of microfill and hybrid composites. Flexural test specimens (N = 75) were prepared according to International Organization for Standardization (ISO) 4049 specifications (25 x 2 x 2 mm) by using a standard metallic mold. Materials used and groups were as follows (N = 15): group 1: hybrid composite (Clearfil APX, Kuraray Co.Ltd, Osaka, Japan); group 2: microfill composite (Clearfil ST, Kuraray Co.Ltd.); group 3: hybrid + microfill composite; group 4: woven glass fiber (EverstickNet, StickTech Ltd, Turku, Finland) + hybrid composite; group 5: woven glass fiber + microfill composite. The specimens were stored in distilled water at 37 degrees C for 7 days. Afterward, they were loaded to fracture (1 mm/min) by using a universal testing machine (AG-50 kNG Shimadzu Co., Kyoto, Japan). Flexural strengths were expressed as maximum flexural load per cross-sectional area of the specimen. The results were statistically analyzed with Kruskall-Wallis and Mann-Whitney U tests (p 0.01). Glass fiber layering of microfill and hybrid composites presented higher flexural strength, and veneering of hybrid composite with microfill composite increased the resistance of the restoration. Glass fiber reinforcement of both hybrid and microfill resin composite materials may be a clinical option in otherwise unfavorable clinical conditions, such as large cavities and/or where bruxism is in present restorative dentistry