5 research outputs found
Pili mediated intercellular forces shape heterogeneous bacterial microcolonies prior to multicellular differentiation
No full textA virulence-associated filamentous bacteriophage of Neisseria meningitidis increases host-cell colonisation
No full textExtracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion
No full textDNA-uptake pili of Vibrio cholerae are required for chitin colonization and capable of kin recognition via sequence-specific self-interaction
No full textSpatial structure, cooperation and competition in biofilms
No full textBiofilm formation, in which cells form matrix-enclosed communities, is a major mode of microbial life. The study of biofilms has revealed vast complexity both in terms of their resident species composition and phenotypic diversity. Despite this complexity, theoretical and experimental work in the past decade has identified common principles for understanding microbial biofilms. In this Review, we discuss how the spatial arrangement of genotypes within a community influences the cooperative and competitive cell-cell interactions that define biofilm form and function. Furthermore, we argue that a perspective rooted in ecology and evolution is fundamental to progress in microbiology
