Understanding the internal structures of the X(4140)X(4140), X(4274)X(4274), X(4500)X(4500) and X(4700)X(4700)

We investigate the newly observed $X(4500)$ and $X(4700)$ based on the diquark-antidiquark configuration within the framework of QCD sum rules. Both of them may be interpreted as the $D$-wave $cs\bar{c}\bar{s}$ tetraquark states of $J^P = 0^+$, but with opposite color structures, which is remarkably similar to the result obtained in Ref.~\cite{Chen:2010ze} that the $X(4140)$ and $X(4274)$ can be both interpreted as the $S$-wave $cs\bar{c}\bar{s}$ tetraquark states of $J^P = 1^+$, also with opposite color structures. However, the extracted masses and these suggested assignments to these $X$ states do depend on these running quark masses where m_s (2 \mbox{ GeV}) = 95 \pm 5 MeV and $m_c (m_c) = 1.23 \pm 0.09$ GeV. As a byproduct, the masses of the hidden-bottom partner states of the $X(4500)$ and $X(4700)$ are extracted to be both around 10.64 GeV, which can be searched for in the $\Upsilon \phi$ invariant mass distribution.Comment: 6 pages, 4 figures. Accepted by Eur. Phys. J.

a1(1420)a_1(1420) resonance as a tetraquark state and its isospin partner

We systematically construct tetraquark currents of $I^GJ^{PC}=1^-1^{++}$ and classify them into types $\mathbf{A}$ (antisymmetric), $\mathbf{S}$ (symmetric) and $\mathbf{M}$ (mixed), based on flavor symmetries of diquarks and antidiquarks composing the tetra quark currents. We use tetraquark currents of type $\mathbf{M}$ to perform QCD sum rule analyses, and find a tetraquark current $\eta^M_{5\mu}$ with quark contents $q s\bar q \bar s$($q=u$ or $d$) leading to a mass of $1.44 \pm 0.08$ GeV consistent with the $a_1(1420)$ state recently observed by the COMPASS collaboration. Our results support tetraquark explanations for both $a_1(1420)$ and $f_1(1420)$, assuming that they are isospin partners. We also study their possible decay patterns. As tetraquark candidates, the possible decay modes of $a_1(1420)$ are $S$-wave $a_1(1420) \rightarrow K^*(892)K$ and $P$-wave $a_1(1420)\rightarrow f_0(980) \pi$ while the possible decay patterns of $f_1(1420)$ are $S$-wave $f_1(1420) \rightarrow K^*(892)K$ and $P$-wave $f_1(1420) \rightarrow a_0(980) \pi$. We speculate that $a_1(1420)$ is partly responsible for the large isospin violation in the $\eta(1405)\to f_0(980)\pi_0$ decay mode which is reported by BESIII collaboration in the $J/\psi\to\gamma 3\pi$ process.Comment: 15 pages, 8 figures. Accepted by Phys. Rev.

Overexpression of an isoform of AML1 in acute leukemia and its potential role in leukemogenesis

AML1/RUNX1 is a critical transcription factor in hematopoietic cell differentiation and proliferation. From the _AML1_ gene, at least three isoforms, _AML1a_, _AML1b_ and _AML1c_, are produced through alternative splicing. AML1a interferes with the function of AML1b/1c, which are often called AML1. In the current study, we found a higher expression level of _AML1a_ in ALL patients in comparison to the controls. Additionally, AML1a represses transcription from promotor of macrophage-colony simulating factor receptor (M-CSFR) mediated by AML1b, indicating that AML1a antagonized the effect of AML1b. In order to investigate the role of _AML1a_ in hematopoiesis and leukemogenesis _in vivo_, bone marrow mononuclear cells (BMMNCs) from mice were transduced with AML1a and transplanted into lethally irradiated mice, which develop lymphoblastic leukemia after transplantation. Taken together, these results indicate that overexpression of AML1a may be an important contributing factor to leukemogenesis