The hypoactive corpora cavernosa with degenerative erectile dysfunction: a new syndrome

BACKGROUND: In a group of 22 patients with erectile dysfunction, vasculogenic, neurogenic, endocrinologic or psychogenic investigations failed to find a cause for their erectile dysfunction. The electro-cavernosograms of these patients recorded a diminished activity. We investigated the hypothesis that diminished corpus cavernosum electromyography activity was the cause of erectile dysfunction in these patients. METHODS: The study comprised the above mentioned 22 patients (study group, 43.8 ± 5.9 SD years) and 15 healthy volunteers (control group, 41.8 ± 5.1 SD years). The electro-cavernosograms were recorded in the flaccid, erectile and detumescent phases by 2 electrodes inserted into the corpus cavernosum. RESULTS: The electro-cavernosogram of the healthy volunteers registered in the flaccid phase regular slow waves and random action potentials. The wave variables declined significantly in the erectile phase (p < 0.01). In the study group, the slow wave variables in the flaccid phase exhibited a significant decrease (p < 0.05) compared to the healthy volunteers, and the rhythm was irregular. Erection did not occur with sildenafil administration or intracavernosal papaverine injection, and penile implant was performed. Biopsy examination showed degenerated muscle fibers, and fragmented collagen and elastic fibers with areas of fibrosis. CONCLUSION: A novel concept of the cause of erectile dysfunction was presented. Corpora cavernosa showed degenerative changes on histopathologic examination and exhibited diminished electromyography activity. They did not respond to sildenafil administration or intracavernosal papaverine injection. Penile implants were the only treatment. The condition is given the name 'hypoactive corpus cavernosum'. The cause of corpus cavernosum degenerative changes needs further study

Male sexual desire disorder

In the literature hypoactive sexual desire is the most frequently studied entity in the male sexual desire domain. In this chapter it is extensively discussed. Moreover, some facets of male hyperactive sexual desire are discussed. Hypoactive sexual desire is associated with multiple biological and psychological causes Sexual desire is easily disturbed. Uncomplicated experience of sexual desire appears to demand that all physical and psychological systems involved function optimally. The fact that decreased sexual desire is a ‘final common pathway’ of a diverse range of causes has not contributed to stimulation of scientific research into these factors. The number of properly controlled studies into pharmacological treatment of men with decreased sexual desire is very limited. There are no studies with control groups in the current literature on the psychological treatment of the problems men with hypoactive sexual desire suffer from. Cognitive behavioural therapy is possibly an effective approach; however, this observation has only been done in one single study in women

Device, system and method for characterising a motion pattern

\u3cp\u3eThe present invention relates to a device for caracterizing the sexual disfunction of a person, comprising: a holder; means for attaching the holder to the person; means arranged in the holder for determining during use the motion pattern of the person, which motion pattern-determining means comprise: at least one acceleration transducer for determining the acceleration values in at least one direction of the movements performed by the person as a function of time. The invention also relates to a method for characterizing the sexual disfunction of a person, comprising of: attaching at least one acceleration transducer to the body of the person; measuring the acceleration values of the body of the person in at least one direction as a function of time; determining the time duration between penetration and ejaculation by the person on the basis of the measured acceleration values.\u3c/p\u3