922 research outputs found
Comparison of mechanical debridement and radiofrequency energy for chondroplasty in an in vivo equine model of partial thickness cartilage injury
SummaryObjectiveThe purpose of this study was to develop a long-term model of cartilage injury that could be used to compare the effects of radiofrequency energy (RFE) and mechanical debridement as a treatment.MethodsPartial thickness fibrillation of patellar cartilage was created in 16 mature ponies. Three months after the initial surgery all injured patellae were randomly selected to receive one of the four treatments (n=8/treatment): (1) control, (2) mechanical debridement with a motorized shaver, (3) TAC-CII RFE probe, and (4) CoVac 50 RFE probe. The ponies were euthanized 22 months after treatment. Macroscopic appearance of the cartilage surface was scored, vital cell staining was used to determine chondrocyte viability and light microscopy was used to grade the morphometric changes within the cartilage. Mechanical properties (aggregate modulus, Poisson's ratio and permeability) also were determined and compared to normal uninjured cartilage.ResultsThere were no differences in the cartilage surface scores among the treatment groups and control samples (P>0.05). The maximum depth of cell death and the percentage of dead area in control and mechanical debridement groups were significantly less than those in both RFE groups. There were no significant differences in maximum depth and the percentage of dead area between the two RFE treatment groups. Histologic scores demonstrated better cartilage morphology for the control and mechanical debridement groups than those of RFE groups. However, even with full thickness chondrocyte death, the matrix in the RFE treated sections was still retained and the mechanical properties of the treated cartilage did not differ from the mechanical debridement group.ConclusionRFE caused greater chondrocyte death and more severe morphological changes compared to untreated degenerative cartilage and mechanical debridement in this model
Chiral properties of domain-wall fermions from eigenvalues of 4 dimensional Wilson-Dirac operator
We investigate chiral properties of the domain-wall fermion (DWF) system by
using the four-dimensional hermitian Wilson-Dirac operator. We first derive a
formula which connects a chiral symmetry breaking term in the five dimensional
DWF Ward-Takahashi identity with the four dimensional Wilson-Dirac operator,
and simplify the formula in terms of only the eigenvalues of the operator,
using an ansatz for the form of the eigenvectors. For a given distribution of
the eigenvalues, we then discuss the behavior of the chiral symmetry breaking
term as a function of the fifth dimensional length. We finally argue the chiral
property of the DWF formulation in the limit of the infinite fifth dimensional
length, in connection with spectra of the hermitian Wilson-Dirac operator in
the infinite volume limit as well as in the finite volume.Comment: Added a reference and modified the acknowledgmen
The Importance of Time Congruity in the Organisation.
In 1991 Kaufman, Lane, and Lindquist proposed that time congruity in terms of an individual's time preferences and the time use methods of an organisation would lead to satisfactory performance and enhancement of quality of work and general life. The research reported here presents a study which uses commensurate person and job measures of time personality in an organisational setting to assess the effects of time congruity on one aspect of work life, job-related affective well-being. Results show that time personality and time congruity were found to have direct effects on well-being and the influence of time congruity was found to be mediated through time personality, thus contributing to the person–job (P–J) fit literature which suggests that direct effects are often more important than indirect effects. The study also provides some practical examples of ways to address some of the previously cited methodological issues in P–J fit research
Giant magnetothermopower of magnon-assisted transport in ferromagnetic tunnel junctions
We present a theoretical description of the thermopower due to
magnon-assisted tunneling in a mesoscopic tunnel junction between two
ferromagnetic metals. The thermopower is generated in the course of thermal
equilibration between two baths of magnons, mediated by electrons. For a
junction between two ferromagnets with antiparallel polarizations, the ability
of magnon-assisted tunneling to create thermopower depends on the
difference between the size of the majority and
minority band Fermi surfaces and it is proportional to a temperature dependent
factor where is the magnon Debye
energy. The latter factor reflects the fractional change in the net
magnetization of the reservoirs due to thermal magnons at temperature
(Bloch's law). In contrast, the contribution of magnon-assisted
tunneling to the thermopower of a junction with parallel polarizations is
negligible. As the relative polarizations of ferromagnetic layers can be
manipulated by an external magnetic field, a large difference results in a magnetothermopower effect. This
magnetothermopower effect becomes giant in the extreme case of a junction
between two half-metallic ferromagnets, .Comment: 9 pages, 4 eps figure
Opioid overdose mortality among former North Carolina inmates: 2000-2015
Objectives. To examine differences in rates of opioid overdose death (OOD) between former North Carolina (NC) inmates and NC residents and evaluate factors associated with postrelease OOD. Methods. We linked NC inmate release data to NC death records, calculated OOD standardized mortality ratios to compare former inmates with NC residents, and calculated hazard ratios to identify predictors of time to OOD. Results. Of the 229 274 former inmates released during 2000 to 2015, 1329 died from OOD after release. At 2-weeks, 1-year, and complete follow-up after release, the respective OOD risk among former inmates was 40 (95% confidence interval [CI] = 30, 51), 11 (95% CI = 9.5, 12), and 8.3 (95% CI = 7.8, 8.7) times as high as general NC residents; the corresponding heroin overdose death risk among former inmates was 74 (95% CI = 43, 106), 18 (95% CI = 15, 21), and 14 (95% CI = 13, 16) times as high as general NC residents, respectively. Former inmates at greatest OOD risk were those within the first 2 weeks after release, aged 26 to 50 years, male, White, with more than 2 previous prison terms, and who received in-prison mental health and substance abuse treatment. Conclusions. Former inmates are highly vulnerable to opioids and need urgent prevention measures
The effect of rare regions on a disordered itinerant quantum antiferromagnet with cubic anisotropy
We study the quantum phase transition of an itinerant antiferromagnet with
cubic anisotropy in the presence of quenched disorder, paying particular
attention to the locally ordered spatial regions that form in the Griffiths
region. We derive an effective action where these rare regions are described in
terms of static annealed disorder. A one loop renormalization group analysis of
the effective action shows that for order parameter dimensions the rare
regions destroy the conventional critical behavior. For order parameter
dimensions the critical behavior is not influenced by the rare regions,
it is described by the conventional dirty cubic fixed point. We also discuss
the influence of the rare regions on the fluctuation-driven first-order
transition in this system.Comment: 6 pages RevTe
A two-species model of a two-dimensional sandpile surface: a case of asymptotic roughening
We present and analyze a model of an evolving sandpile surface in (2 + 1)
dimensions where the dynamics of mobile grains ({\rho}(x, t)) and immobile
clusters (h(x, t)) are coupled. Our coupling models the situation where the
sandpile is flat on average, so that there is no bias due to gravity. We find
anomalous scaling: the expected logarithmic smoothing at short length and time
scales gives way to roughening in the asymptotic limit, where novel and
non-trivial exponents are found.Comment: 7 Pages, 6 Figures; Granular Matter, 2012 (Online
Reevaluation of the role of nuclear uncertainties in experiments on atomic parity violation with isotopic chains
In light of new data on neutron distributions from experiments with
antiprotonic atoms [ Trzcinska {\it et al.}, Phys. Rev. Lett. 87, 082501
(2001)], we reexamine the role of nuclear-structure uncertainties in the
interpretation of measurements of parity violation in atoms using chains of
isotopes of the same element. With these new nuclear data, we find an
improvement in the sensitivity of isotopic chain measurements to ``new
physics'' beyond the standard model. We compare possible constraints on ``new
physics'' with the most accurate to date single-isotope probe of parity
violation in the Cs atom. We conclude that presently isotopic chain experiments
employing atoms with nuclear charges Z < 50 may result in more accurate tests
of the weak interaction.Comment: 6 pages, 1 fig., submitted to Phys. Rev.
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