"Tomography" of the cluster structure of light nuclei via relativistic dissociation

These lecture notes present the capabilities of relativistic nuclear physics for the development of the physics of nuclear clusters. Nuclear track emulsion continues to be an effective technique for pilot studies that allows one, in particular, to study the cluster dissociation of a wide variety of light relativistic nuclei within a common approach. Despite the fact that the capabilities of the relativistic fragmentation for the study of nuclear clustering were recognized quite a long time ago, electronic experiments have not been able to come closer to an integrated analysis of ensembles of relativistic fragments. The continued pause in the investigation of the "fine" structure of relativistic fragmentation has led to resumption of regular exposures of nuclear emulsions in beams of light nuclei produced for the first time at the Nuclotron of the Joint Institute for Nuclear Research (JINR, Dubna). To date, an analysis of the peripheral interactions of relativistic isotopes of beryllium, boron, carbon and nitrogen, including radioactive ones, with nuclei of the emulsion composition, has been performed, which allows the clustering pattern to be presented for a whole family of light nuclei.Comment: ISBN 978-3-319-01076-2. 55 pages, 28 figure

Clinical efficacy of dry nutritional treatment products for phenylketonuria in children, adults, and pregnant women: study results

N.A. Semenova1, G.V. Baydakova1, N.V. Nikitina2, V.K. Podolina2, E.Yu. Belyashova3,&nbsp;V.N. Kuznetsova3, E.M. Kochegurova4, L.P. Andreeva5, O.N. Khaylova5, S.I. Kutsev1 1Research Centre for Medical Genetics, Moscow, Russian Federation 2Clinical and Diagnostic Center “Protection of Health of Mother and Child”, Yekaterinburg, Russian Federation 3Orenburg Regional Clinical Hospital No. 2, Orenburg, Russian Federation 4E.M. Bakunina Regional Clinical Perinatal Center, Tver, Russian Federation 5Saratov Regional Children’s Clinical Hospital, Saratov, Russian Federation Abstract Aim: to assess the efficacy of domestic nutritional treatment products for phenylketonuria (PKU) in children, adults, and pregnant women. Patients and Methods: 46 patients with verified PKU were enrolled in this open-label multicenter prospective non-controlled study. Patients were allocated to the groups depending on nutritional treatment products which were prescribed according to the Clinical Guidelines of the Ministry of Health of Russian Federation. Clinical efficacy of the products was assessed according to the Good Clinical Practice guidelines based on clinical and laboratory tests. Results: all patients taken nutritional treatment products throughout the study. No dyspepsia, abnormal poop, or allergic reactions were reported. Most patients reported on more pleasant smell and odor of the products as compared with the products taken previously. At baseline, mean phenylalanine levels were within normal limits. After the treatment, phenylalanine levels were stable&nbsp; in all patients. Clinical and biochemical tests were within normal limits. Conclusion: dry nutritional treatment products are highly effective in children, adults, and pregnant women with PKU. Keywords: phenylketonuria, specialized food, phenylalanine, mixture, products. For citation: Semenova N.A., Baydakova G.V., Nikitina N.V. et al. Clinical efficacy of dry nutritional treatment products for phenylketonuria in children, adults, and pregnant women: study results. Russian Journal of Woman and Child Health. 2019;2(4):355–360. <br

Influence of the impregnation order on the synergy between Ag and V2O5/TiO2 catalysts in the total oxidation of Cl-aromatic VOC

Silver is added to V2O5/TiO2 catalysts by a wet impregnation method and the influence of the impregnation order is studied. Silver and vanadia were introduced by co-impregnation or by impregnation in 2 steps (V first or Ag first). Vanadia loading always corresponds to 2.49 wt% while 9 different loadings of silver were explored (0.02–12.5 wt%). Whatever the way of synthesis, the addition of silver to V2O5/TiO2 formulation induces: (i) a decrease of the specific surface; (ii) a higher vanadium oxidation state and (iii) a decrease of the Brønsted acidity. A synergy can be evidenced for the co-impregnated Ag–V2O5/TiO2 catalysts in the total oxidation of chlorobenzene. This synergy is observed for several loadings of Ag with a maximum at a loading of 0.05 wt%. This synergy can be related to the higher oxidation state of vanadium induced by silver, to the minimum decrease of the specific surface and to the absence of AgCl at the surface of the catalysts. This last aspect is confirmed via the investigation of the catalytic performances in the total oxidation of benzene. In this system, a synergy is observed for the co-impregnated catalysts and when the vanadium is impregnated first. On the contrary, no synergy was observed when silver is impregnated first. This result suggests that the synergy can be obtained only if the vanadium keeps a direct interaction with the support and if a good “degree of accessibility” of the gaseous phase to the silver species is maintained