Air Pollen Monitoring in a Specific Region as a Part of the Pollinosis Prevention

Background: The prevalence and severity of allergic diseases, including pollinosis, are increasing worldwide. Hay fever develops due to the complex interaction of genes and manifests itself due to exogenous factors. The main environmental etiology of allergy is plant pollen. Continuous study and analysis of the air pollen spectrum constitute the basis of air monitoring and are important in developing preventive measures for allergic diseases.   Objective: To perform an air pollen monitoring in Kr snodar and to assess the treatment of patients with pollinosis in various cities and districts of the Krasnodar Region according to the Krasnodar Regional Allergy Center data.   Materials and methods: We retrospectively analyzed the patients seeking medical care due to allergy in the Krasnodar Region using the statistical data obtained in 2022 from the Krasnodar Regional Allergy Center. We assessed the effects of air pollen pollution according to the data of air pollen monitoring in Krasnodar during the main activity of herbaceous plants’ taxa (from April 1, 2022 to October 31, 2022). We used AeRobiology and Microsoft Excel 2010 tools for data processing and development of the main parameters of the pollen season.   Results: According to the Krasnodar Regional Allergy Center data, there were 37,212 people diagnosed with J45.0, J46 and 20,012 people diagnosed with J30.1-30.4 in 2022. We identified 8 allergenic taxa of herbaceous plants in the Krasnodar air. We found that the total seasonal pollen concentration increased by an average of 1.8 in 2022 compared to previous monitoring periods in 2018-2021.   Conclusions: Comparative assessment of the prevalence of pollinosis and the air pollen monitoring are important for effective medical care

THE TOPIC OF KINSHIP IN THE NEW TESTAMENT

Traditionally the excerpt from Matthew 12. 46-50 (paral.) is interpreted in terms ofbiographical genre as Christ’s teaching essential to Christian concept of familia Dei andat the same time as a role model given by the Teacher to His pupils. The article deals withthe reasons for interpretation of the excerpt according to the genre of “typological exe-gesis” as a messianic allusion to Deuteronomy 33. 8-11, that is to say: 1) there are argu-ments testifying that Christian tradition might have related a holy man from the passage,Deuteronomy 33. 8-11, to character of Moses, who is the typological prototype of Christin Christian tradition; 2) author examines the structure of certain units of the text fromthe synoptic Gospels and shows the outstanding nature and messianic significance of theexcerpt Matthew 12. 46 ff. and paral.; 3) the article contains evidence from the writingsof Fathers of the Church, early Christian and Qumran traditions, revealing relationsbetween lack of kinship, abnegation from family and predestination to higher ministry.The interpretation offered here does not rule out the traditional commentary to Matthew12. 46 ff. completely, but offers an additional way of interpreting the episo

Antibiotic therapy for acute respiratory viral infections in children:what do parents know about antibiotics and antibiotic resistance?

One of the causes of antibiotic resistance (AR) is irrational use of antibiotics (ABs) that are commonly administered to patients with acute respiratory viral infections (ARVIs). Rational AB use largely depends on the awareness of people. Objective. To analyze the awareness of people about AR and AB use, as well as to assess the attitude to AB therapy among parents of preschool children. Materials and methods. We conducted anonymous survey among 513 parents of preschool children in Tomsk. Results. Almost two-thirds (61.6%) of respondents admitted that their children received AB during cold/flu/ARVI. The most commonly used ABs were amoxicillin (62.3%), azithromycin (19.7%), and amoxicillin with clavulanic acid (11.1%). The majority of patients administered ABs to their children only after doctor's prescription (80.4%) and adhered to treatment regimen (79.7%). A total of 65.8% respondents stated that doctors had explained why AB therapy was necessary. Nearly two out of three parents (62.4%) believed that ABs may have a negative impact on health. More than half of the respondents were aware of AR. Conclusion. The majority of parents use antibiotics to treat ARVI in their children only with doctor's prescription. However, we observed insufficient awareness about AR, AB use, and possible side effects, which necessitates the development of educational programs for the population

Assessing the Efciency of Detection of Vibrio cholerae Genetic Determinants Through Waterbody Vibrioflora Monitoring System

Objective of the study was to assess the effectiveness of PCR screening of Vibrio cholerae genetic determinants in samples from surface water reservoirs for optimization of the cholera microbiological monitoring system.Materials and methods. The study was carried out as a part of the vibrioflora monitoring in surface water bodies in Irkutsk city. The study design included: 1) PCR screening of V. cholerae genetic determinants in nutrient-enriched (1 % peptone water) samples from surface water reservoirs during the monitoring period (824 samples); 2) studying of the V. cholerae DNA accumulation dynamics applying PCR assay of the samples from surface water reservoirs during cultivation on the enriched media (16 samples in dynamics); 3) experimental study of the detected V. cholerae concentrations in samples from surface water reservoirs. Species-specifc (hlyA, toxR) and serogroup-specifc (wbeT, wbfR) V. cholerae determinants were indicated in PCR with hybridization-fluorescent and electrophoretic detection.Results and discussion. At the frst stage it was found that the proportion of the positive samples through PCR screening (33.9 %) exceeded the percentage of the positive samples in bacteriological examination (19.3 %) (t=6.6; p<0,01). In the assessment of DNA accumulation dynamics, a decrease in the threshold cycle (Ct) by 1.2–5.2 times was recorded, indicating an increase in the V. cholerae concentration and proving the detection of genetic determinants of viable forms during PCR screening. An extended study of PCR-positive but bacteriologically negative samples made it possible to additionally isolate 4 V. cholerae cultures. However, there were no differences in the sensitivity of PCR screening and bacteriological analysis in the experiment with water samples artifcially contaminated with V. cholerae unlike the analysis of the enriched native samples. It can be determined by the metabolism and adaptation peculiarities of the microorganism in different environmental conditions. The results of the integrated study indicate the epidemiological effectiveness of PCR screening which gives grounds to recommend its application in monitoring studies of vibrioflora from environment after preliminary enrichment on liquid nutrient media in the work of federal, territorial, and regional laboratories

The Directions of FinTech Development in Russia: Expert Opinion of the Financial University

The active digitalization of the life of modern society observed over the past 20 years has led to real changes in the economy. The financial sector is at the heart of a digital transformation that has been spearheaded by FinTech, which is now shaping a new segment of modern financial markets. At the same time, the most wellknown objects of FinTech are cryptocurrency and token. Cryptocurrencies, regardless of the attitude of regulatory authorities to them, have become a virtual reality of the financial sector and are actively used to pay for goods and services. The peculiarity of cryptocurrencies is its anonymity and unaccountability of the state that defines a range of risks to society and the state. However, cryptocurrencies, along with risks, create opportunities — from the development of innovative technologies to the creation of new jobs and replenishment of the national budget. The penetration of FinTech into the financial market segments traditionally occupied by banks gave rise to a discussion about their future. However, it will probably not be the displacement of the banks but their FinTech transformation. An example of this is the payment industry, which has become one of the main consumers of the latest financial technologies and provides a wide range of opportunities for FinTech companies to develop. An important element of FinTech is RegTech (Regulatory Technology), which allows companies to bypass trade barriers and helps build a constructive dialogue with regulators. In turn, SupTech (Supervision Technology) is used for analysis and forecasting purposes. At the end of the article, based on the analysis of foreign experience, we formulated the main approaches, the implementation of which allows states to stimulate the introduction and development of new financial technologies, as well as we analysed the experience of interstate coordination of cooperation in the field of financial technologies in the EU and the EAEU countries