MOLLUSCUM CONTAGIOSUM WITH CHILDREN: PECULIARITIES OF COURSE AND MODERN APPROACHES TO THERAPY

The article deals with the main aspects of the epidemiology and clinical course of molluscum contagiosum with children. Comparative analysis of the effectiveness  of different treatment  methods has been done. Based on the data of multicenter clinical studies, the authors concluded that the high efficiency and good tolerance  of 5% potassium hydroxide solution in the treatment  of molluscum contagiosum with children children

ЗУДЯЩИЕ ДЕРМАТОЗЫ С ХРОНИЧЕСКИМ ТЕЧЕНИЕМ В ДЕТСКОМ ВОЗРАСТЕ: СОВРЕМЕННЫЕ МЕТОДЫ ЛЕЧЕНИЯ И ЭФФЕКТИВНОГО КУПИРОВАНИЯ СУБЪЕКТИВНЫХ ЖАЛОБ

The article presents contemporary data on the peculiarities of etiology and pathogenesis of chronic itching dermatosis in children. We provide classification of various itching forms and pathophysiological mechanism of the development thereof underlying chronic skin disorders. We describe results of clinical studies of effectiveness and safety of methylprednisolone aceponate for treating itching dermatosis in children.В статье представлены современные данные об особенностях этиологии и патогенеза зудящих дерматозов с хроническим течением у детей. Приведена классификация различных форм зуда и патофизиологический механизм его развития, лежащего в основе хронических заболеваний кожи. Освещены результаты клинических исследований эффективности и безопасности метилпреднизолона ацепоната в лечении зудящих дерматозов в детском возрасте

КОНТАГИОЗНЫЙ МОЛЛЮСК У ДЕТЕЙ: ОСОБЕННОСТИ ТЕЧЕНИЯ И СОВРЕМЕННЫЕ ПОДХОДЫ К ТЕРАПИИ

The article deals with the main aspects of the epidemiology and clinical course of molluscum contagiosum with children. Comparative analysis of the effectiveness  of different treatment  methods has been done. Based on the data of multicenter clinical studies, the authors concluded that the high efficiency and good tolerance  of 5% potassium hydroxide solution in the treatment  of molluscum contagiosum with children children.В статье освещены основные особенности эпидемиологии и клинического течения контагиозного моллюска у детей. Проведен  сравнительный  анализ  эффективности  различных  методов терапии заболевания.  На основании данных многоцентровых клинических исследований  авторами сделан  вывод о высокой результативности и хорошей переносимости 5% раствора гидроксида калия при лечении контагиозного моллюска в детском возрасте

PRINCIPLES THERAPY OF ATOPIC DERMATITIS IN CHILDHOOD IN THE ASPECT OF MODERN CONCEPTS OF THE PATHOGENESIS OF THE DISEASE

The article contains data on the key links in the pathogenesis of atopic dermatitis in children. The authors of the article have covered modern approaches to topical therapy of atopic dermatitis in children. Modern algorithms of proactive therapy and control over the course of the disease are presented

CHRONIC ITCHING DERMATOSIS IN CHILDREN: MODERN METHODS OF TREATMENT AND EFFICIENT TERMINATION OF SUBJECTIVE COMPLAINTS

The article presents contemporary data on the peculiarities of etiology and pathogenesis of chronic itching dermatosis in children. We provide classification of various itching forms and pathophysiological mechanism of the development thereof underlying chronic skin disorders. We describe results of clinical studies of effectiveness and safety of methylprednisolone aceponate for treating itching dermatosis in children

Topical treatment of atopic dermatitis in children: current challenges and answers

Atopic dermatitis (AD) is the most prevalent skin disease in the early childhood and is a considerable problem both for patients and members of their families and for the society on the whole. In most cases, AD requires a long-term therapy such as the use of anti-inflammatory drugs. Selective inhibitors of the synthesis and release of proinflammatory cytokines - topical calcineurin inhibitors (Tcis) - are now used to solve this problem, with pimecrolimus being one of them. Pimecrolimus has been thoroughly examined for the past decade in different clinical studies involving a total of over 4,000 infants (below 2 years of age). These studies demonstrated the efficacy and safety of pimecrolimus for AD in children provided it is used in a long-term therapy on an intermittent basis. Unlike topical corticosteroids, the long-term use of pimecrolimus is not associated with any risk of development of systemic immunosuppression, skin atrophy, skin barrier dysfunction or systemic absorption so it is safe even if applied to the most sensitive skin areas. In view of this, the authors make a conclusion that pimecrolimus used in the form of a cream is a safe and efficient drug for the treatment of infants aged over three months suffering from atopic dermatitis