16 research outputs found
Neptune to the Common-wealth of England (1652): the republican Britannia and the continuity of interests
In the seventeenth century, John Kerrigan reminds us, “models of empire did not always turn on monarchy”. In this essay, I trace a vision of “Neptune’s empire” shared by royalists and republicans, binding English national interest to British overseas expansion. I take as my text a poem entitled “Neptune to the Common-wealth of England”, prefixed to Marchamont Nedham’s 1652 English translation of Mare Clausum (1635), John Selden’s response to Mare Liberum (1609) by Hugo Grotius. This minor work is read alongside some equally obscure and more familiar texts in order to point up the ways in which it speaks to persistent cultural and political interests. I trace the afterlife of this verse, its critical reception and its unique status as a fragment that exemplifies the crossover between colonial republic and imperial monarchy at a crucial moment in British history, a moment that, with Brexit, remains resonant
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Inundation Modeling of a Potential Glacial Lake Outburst Flood in Huaraz, Peru
One of the consequences of recent glacier recession is the formation and rapid growth of
lakes formed at the snout of glaciers. One risk is that moraines damming these glacial lakes
could fail releasing a huge volume of water and creating a glacial lake outburst flood. This
happened December 13, 1941, at Lake Palcacocha, Peru, flooding the city of Huaraz and killed
several thousand people. Recently Lake Palcacocha has been declared in a state of emergency
state because its volume has again reached dangerous levels, threatening a flood that would
quickly reach Huaraz causing major devastation and potentially loss of life. An analysis has been
performed of the glacial hazards for the city of Huaraz from Lake Palcacocha. This analysis
consists of physical models of each process in the chain of events that results in a glacial lake
outburst flood: rock and ice avalanche; wave generation, propagation and moraine overtopping;
terminal moraine breaching and draining of the lake; and downstream inundation and impacts in
the city of Huaraz. Two scenarios of moraine erosion were simulated: a worst-case event of a 56
m breach and a smaller 22.5 m erosion event. These scenarios showed that flood reaches the City
of Huaraz 1.06 and 1.20 hours after the avalanche for the 56 m and 22.5 m events, respectively.
The inundation in the city is extensive in both breaching events with depths exceeding 1 m in
many areas, especially near the channel of the Quillcay River, and the velocity of the flood
exceeding 1 m/s in most of this area. Because of the inundation depth and the velocity of the
flow, most of the area of the city that experiences flooding will have a very high hazard level,
putting both lives and property at risk.Center for Research in Water Resource
The aetiology of experimental fibrosing alveobronchiolitis induced in rats by paprika dust.
‘Proclaim Liberty Throughout All the Land unto All the Inhabitants Thereof!’:Reading Leviticus 25:10 Through the Centuries
‘Proclaim liberty throughout all the land unto all the inhabitants thereof!’ Reading Leviticus 25:10 through the centuries
Atopic dermatitis phenotypes in childhood.
none6noBackground
Atopic dermatitis (AD) is a chronic inflammatory skin disease and can be the first step of the atopic march.
Objective
In this retrospective study, we analysed the immunological and clinical patterns of AD in a group of children affected by the disease since their first years of life, in order to evaluate if and how these patterns can change over time, and to identify biomarkers that can possibly correlate with the clinical phenotype.
Methods
We enrolled Caucasian children with diagnosis of AD performed by a specialist on the basis of Hanifin and Rajka?s criteria and with a first clinical and laboratory evaluation before 5?years of age. Patients were divided in 2 groups: IgE-associated AD (with or without allergic respiratory diseases) and non-IgE-associated AD.
Results
Among 184 patients enrolled in this study, at the beginning 30/184 were classified as having non-IgE-associated AD, but during follow-up, at the median age of 36?months, 15 patients became allergic. All 15 patients who switched from the non-IgE to the IgE-associated form had a significantly earlier onset of AD than those who did not switch. Dust mite sensitization seem to be the best biomarker (OR 2.86) to predict the appearance of allergic respiratory diseases.
Conclusion
IgE-associated AD is more frequent in childhood than non-IgE-associated AD. These two phenotypes are different in the age of onset and in the remission patterns. In the first years of life, it is important to distinguish the different phenotypes in order to evaluate possible allergic related conditions.noneRicci G; Dondi A; Neri I; Ricci L; Patrizi A; Pession A.Ricci G; Dondi A; Neri I; Ricci L; Patrizi A; Pession A