5 research outputs found

    The Changing Waves of Migration from the Balkans to Turkey: A Historical Account

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    Ahmet İçduygu and Deniz Sert tell the history of migration from the Balkans to Turkey from the end of the nineteenth century to the present. They relate this history to nation-building, but also to economic conditions and specific Turkish concerns, such as the perceived need for immigration to compensate for a declining population at that time. They also demonstrate that after 1990, ethnic migration decreased and irregular labour migration became more important

    A Study on the Anticarcinogenic Effects of Calcium Fructoborate

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    Evidences about the preventive and therapeutic effects of boron compounds on cancer have been increasing in the last years. Although calcium fructoborate (CaFB) is used as a nutritional supplement, data about its preventive and therapeutic effects on neoplastic transformations are limited. In the present study, the various concentrations of CaFB were applied to the MDA-MB-231 metastatic breast cancer cell line. First, we examined the cytotoxic effect and IC50 value of CaFB by MTT assay. For the evaluation of the DNA damage, apoptosis and metastatic potential, expression levels of ATM, pATM, PARP, p53, p-p53, caspase-3, caspase-9, and VEGF were investigated by using immunoblotting and immunohistochemical methods. Cell viability was significantly reduced at 50 μM CaFB treatment. pATM, p-p53, and caspase-9 levels increased significantly in all groups; furthermore, there was approximately 12.5-, 2.4-, and 10.7-fold increase, respectively, for 100 μM CaFB treatment. ATM and p53 levels did not change with CaFB treatment, but PARP levels significantly 2.5-fold decreased. While VEGF immunoreactivity decreased in all groups, significant increase in caspase-3 immunoreactivity was observed only in the group treated with 50 μM CaFB (p < 0,001). Our results imply that CaFB may have therapeutic potential as well as preventive benefits in cancer. © 2016, Springer Science+Business Media New York

    The changing waves of migration from the Balkans to Turkey: a historical account

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    Ahmet İçduygu and Deniz Sert tell the history of migration from the Balkans to Turkey from the end of the nineteenth century to the present. They relate this history to nation-building, but also to economic conditions and specific Turkish concerns, such as the perceived need for immigration to compensate for a declining population at that time. They also demonstrate that after 1990, ethnic migration decreased and irregular labour migration became more important
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