Synthesis and Characterization of Electro-Explosive Magnetic Nanoparticles for Biomedical Applications

Nowadays there are new magnetic nanostructures based on bioactive metals with low toxicity and high efficiency for a wide range of biomedical applications including drugs delivery, antimicrobial drugs design, cells' separation and contrasting. For such applications it is necessary to develop highly magnetic particles with less than100 nm in size. In the present study magnetic nanoparticles Fe, Fe[3]O[4] and bimetallic Cu/Fe with the average size of 60- 90 nm have been synthesized by electrical explosion of wire in an oxygen or argon atmosphere. The produced nanoparticles have been characterized with transmission electron microscopy, X-ray phase analysis, and nitrogen thermal desorption. The synthesized particles have shown antibacterial activity to gram-positive (S. aureus, MRSA) and gramnegative (E. coli, P. aeruginosa) bacteria. According to the cytological data Fe, Fe[3]O[4]and Cu/Fe nanoparticles have effectively inhibited viability of cancer cell lines Neuro-2a and J774. The obtained nanoparticles are promising for new antimicrobial drugs and antitumor agents' developmen

Synthesis and Characterization of Electro-Explosive Magnetic Nanoparticles for Biomedical Applications

Nowadays there are new magnetic nanostructures based on bioactive metals with low toxicity and high efficiency for a wide range of biomedical applications including drugs delivery, antimicrobial drugs design, cells' separation and contrasting. For such applications it is necessary to develop highly magnetic particles with less than100 nm in size. In the present study magnetic nanoparticles Fe, Fe[3]O[4] and bimetallic Cu/Fe with the average size of 60- 90 nm have been synthesized by electrical explosion of wire in an oxygen or argon atmosphere. The produced nanoparticles have been characterized with transmission electron microscopy, X-ray phase analysis, and nitrogen thermal desorption. The synthesized particles have shown antibacterial activity to gram-positive (S. aureus, MRSA) and gramnegative (E. coli, P. aeruginosa) bacteria. According to the cytological data Fe, Fe[3]O[4]and Cu/Fe nanoparticles have effectively inhibited viability of cancer cell lines Neuro-2a and J774. The obtained nanoparticles are promising for new antimicrobial drugs and antitumor agents' developmen

Chemical behaviour of Al/Cu nanoparticles in water

Bimetallic Al/Cu nanoparticles with Al/Cu composition 10:90, 20:80, 40:60 were produced by method of simultaneous electrical explosion of metal pairs in the argon atmosphere. Nanopowders containing 20% and 40% (mass) of aluminum interacted with water at 40–70 °C and formed composite particles that were porous structures of nanopetal pseudoboehmite with nanosized copper-containing inclusions inside. Aluminum in nanopowder with Al/Cu composition 10:90 did not react with water, as far as it is in the phase of intermetallic compounds СuAl2 and Сu4Al9. Nanocomposite produced can be used as an active component of antibacterial agents

Study of J/ψJ/\psi and ψ(3686)→Σ(1385)0Σˉ(1385)0\psi(3686)\rightarrow\Sigma(1385)^{0}\bar\Sigma(1385)^{0} and Ξ0Ξˉ0\Xi^0\bar\Xi^{0}

We study the decays of $J/\psi$ and $\psi(3686)$ to the final states $\Sigma(1385)^{0}\bar\Sigma(1385)^{0}$ and $\Xi^0\bar\Xi^{0}$ based on a single baryon tag method using data samples of $(1310.6 \pm 7.0) \times 10^{6}$ $J/\psi$ and $(447.9 \pm 2.9) \times 10^{6}$ $\psi(3686)$ events collected with the BESIII detector at the BEPCII collider. The decays to $\Sigma(1385)^{0}\bar\Sigma(1385)^{0}$ are observed for the first time. The measured branching fractions of $J/\psi$ and $\psi(3686)\rightarrow\Xi^0\bar\Xi^{0}$ are in good agreement with, and much more precise, than the previously published results. The angular parameters for these decays are also measured for the first time. The measured angular decay parameter for $J/\psi\rightarrow\Sigma(1385)^{0}\bar\Sigma(1385)^{0}$, $\alpha =-0.64 \pm 0.03 \pm 0.10$, is found to be negative, different to the other decay processes in this measurement. In addition, the "12\% rule" and isospin symmetry in the $J/\psi$ and $\psi(3686)\rightarrow\Xi\bar\Xi$ and $\Sigma(1385)\bar{\Sigma}(1385)$ systems are tested.Comment: 11 pages, 7 figures. This version is consistent with paper published in Phys.Lett. B770 (2017) 217-22

Observation and study of the decay J/ψ→ϕηη′J/\psi\rightarrow\phi\eta\eta'

We report the observation and study of the decay $J/\psi\rightarrow\phi\eta\eta'$ using $1.3\times{10^9}$ $J/\psi$ events collected with the BESIII detector. Its branching fraction, including all possible intermediate states, is measured to be $(2.32\pm0.06\pm0.16)\times{10^{-4}}$. We also report evidence for a structure, denoted as $X$, in the $\phi\eta'$ mass spectrum in the $2.0-2.1$ GeV/$c^2$ region. Using two decay modes of the $\eta'$ meson ($\gamma\pi^+\pi^-$ and $\eta\pi^+\pi^-$), a simultaneous fit to the $\phi\eta'$ mass spectra is performed. Assuming the quantum numbers of the $X$ to be $J^P = 1^-$, its significance is found to be 4.4$\sigma$, with a mass and width of $(2002.1 \pm 27.5 \pm 21.4)$ MeV/$c^2$ and $(129 \pm 17 \pm 9)$ MeV, respectively, and a product branching fraction $\mathcal{B}(J/\psi\rightarrow\eta{}X)\times{}\mathcal{B}(X\rightarrow\phi\eta')=(9.8 \pm 1.2 \pm 1.7)\times10^{-5}$. Alternatively, assuming $J^P = 1^+$, the significance is 3.8$\sigma$, with a mass and width of $(2062.8 \pm 13.1 \pm 7.2)$ MeV/$c^2$ and $(177 \pm 36 \pm 35)$ MeV, respectively, and a product branching fraction $\mathcal{B}(J/\psi\rightarrow\eta{}X)\times{}\mathcal{B}(X\rightarrow\phi\eta')=(9.6 \pm 1.4 \pm 2.0)\times10^{-5}$. The angular distribution of $J/\psi\rightarrow\eta{}X$ is studied and the two $J^P$ assumptions of the $X$ cannot be clearly distinguished due to the limited statistics. In all measurements the first uncertainties are statistical and the second systematic.Comment: 10 pages, 6 figures and 4 table

Observation of ηc→ωω\eta_c\to\omega\omega in J/ψ→γωωJ/\psi\to\gamma\omega\omega

Using a sample of $(1310.6\pm7.0)\times10^6$ $J/\psi$ events recorded with the BESIII detector at the symmetric electron positron collider BEPCII, we report the observation of the decay of the $(1^1 S_0)$ charmonium state $\eta_c$ into a pair of $\omega$ mesons in the process $J/\psi\to\gamma\omega\omega$. The branching fraction is measured for the first time to be $\mathcal{B}(\eta_c\to\omega\omega)= (2.88\pm0.10\pm0.46\pm0.68)\times10^{-3}$, where the first uncertainty is statistical, the second systematic and the third is from the uncertainty of $\mathcal{B}(J/\psi\to\gamma\eta_c)$. The mass and width of the $\eta_c$ are determined as $M=(2985.9\pm0.7\pm2.1)\,$MeV/$c^2$ and $\Gamma=(33.8\pm1.6\pm4.1)\,$MeV.Comment: 13 pages, 6 figure

Observation of Ds+→pnˉD^+_s\rightarrow p\bar{n} and confirmation of its large branching fraction

The baryonic decay $D^+_s\rightarrow p\bar{n}$ is observed, and the corresponding branching fraction is measured to be $(1.21\pm0.10\pm0.05)\times10^{-3}$, where the first uncertainty is statistical and second systematic. The data sample used in this analysis was collected with the BESIII detector operating at the BEPCII $e^+e^-$ double-ring collider with a center-of-mass energy of 4.178~GeV and an integrated luminosity of 3.19~fb$^{-1}$. The result confirms the previous measurement by the CLEO Collaboration and is of greatly improved precision, which may deepen our understanding of the dynamical enhancement of the W-annihilation topology in the charmed meson decays

Evidence of a resonant structure in the e+e−→π+D0D∗−e^+e^-\to \pi^+D^0D^{*-} cross section between 4.05 and 4.60 GeV

The cross section of the process $e^+e^-\to \pi^+D^0D^{*-}$ for center-of-mass energies from 4.05 to 4.60~GeV is measured precisely using data samples collected with the BESIII detector operating at the BEPCII storage ring. Two enhancements are clearly visible in the cross section around 4.23 and 4.40~GeV. Using several models to describe the dressed cross section yields stable parameters for the first enhancement, which has a mass of 4228.6 \pm 4.1 \pm 6.3 \un{MeV}/c^2 and a width of 77.0 \pm 6.8 \pm 6.3 \un{MeV}, where the first uncertainties are statistical and the second ones are systematic. Our resonant mass is consistent with previous observations of the $Y(4220)$ state and the theoretical prediction of a $D\bar{D}_1(2420)$ molecule. This result is the first observation of $Y(4220)$ associated with an open-charm final state. Fits with three resonance functions with additional $Y(4260)$, $Y(4320)$, $Y(4360)$, $\psi(4415)$, or a new resonance, do not show significant contributions from either of these resonances. The second enhancement is not from a single known resonance. It could contain contributions from $\psi(4415)$ and other resonances, and a detailed amplitude analysis is required to better understand this enhancement

Search for the decay J/ψ→γ+invisibleJ/\psi\to\gamma + \rm {invisible}

We search for $J/\psi$ radiative decays into a weakly interacting neutral particle, namely an invisible particle, using the $J/\psi$ produced through the process $\psi(3686)\to\pi^+\pi^-J/\psi$ in a data sample of $(448.1\pm2.9)\times 10^6$ $\psi(3686)$ decays collected by the BESIII detector at BEPCII. No significant signal is observed. Using a modified frequentist method, upper limits on the branching fractions are set under different assumptions of invisible particle masses up to 1.2 $\mathrm{\ Ge\kern -0.1em V}/c^2$. The upper limit corresponding to an invisible particle with zero mass is 7.0$\times 10^{-7}$ at the 90\% confidence level