10 research outputs found
Properties of Be and C deduced from the folding--potential model
The -- differential cross sections are analyzed in the
optical model using a double--folded potential. With the knowledge of this
potential bound and resonance--state properties of --cluster states in
Be and C as well as astrophysical S--factors of
He(,)Be and Be(,)C are
calculated. --widths and B(E2)--values are deduced.Comment: 2 pages LaTeX, 2 figures can be obtained from the author
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Dynamic change in subcellular localization of signaling proteins is a general concept that eukaryotic cells evolved for eliciting a coordinated response to stimuli. Mass spectrometry-based proteomics in combination with subcellular fractionation can provide comprehensive maps of spatio-temporal regulation of protein networks in cells, but involves laborious workflows that does not cover the phospho-proteome level. Here we present a high-throughput workflow based on sequential cell fractionation to profile the global proteome and phospho-proteome dynamics across six distinct subcellular fractions. We benchmark the workflow by studying spatio-temporal EGFR phospho-signaling dynamics in vitro in HeLa cells and in vivo in mouse tissues. Finally, we investigate the spatio-temporal stress signaling, revealing cellular relocation of ribosomal proteins in response to hypertonicity and muscle contraction. Proteomics data generated in this study can be explored through https://SpatialProteoDynamics.github.io
Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells
Analysis of Li-8(alpha, n)B-11 below the Coulomb barrier in the potential model
The reaction Li-8(alpha, n)B-11 is of interest in inhomogeneous big bang nucleosynthesis. A distorted wave Born approximation calculation employing folding potentials is presented for energies below the Coulomb barrier. The recently observed resonance at about 540 keV center-of-mass energy can be reproduced. The astrophysical S factor is calculated for the ground-state transition as well as for the transitions to the first four excited states of B-11. The reaction rate is derived and compared to literature data. The inclusion of the excited states increases the rate by a factor of 1.5 compared to the ground-state transition.Peer reviewe