Properties of 8^{8}Be and 12^{12}C deduced from the folding--potential model

The $\alpha$--$\alpha$ differential cross sections are analyzed in the optical model using a double--folded potential. With the knowledge of this potential bound and resonance--state properties of $\alpha$--cluster states in $^{8}$Be and $^{12}$C as well as astrophysical S--factors of $^{4}$He($\alpha$,$\gamma$)$^{8}$Be and $^{8}$Be($\alpha$,$\gamma$)$^{12}$C are calculated. $\Gamma_{\gamma}$--widths and B(E2)--values are deduced.Comment: 2 pages LaTeX, 2 figures can be obtained from the author

Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

Dynamic change in subcellular localization of signaling proteins is a general concept that eukaryotic cells evolved for eliciting a coordinated response to stimuli. Mass spectrometry-based proteomics in combination with subcellular fractionation can provide comprehensive maps of spatio-temporal regulation of protein networks in cells, but involves laborious workflows that does not cover the phospho-proteome level. Here we present a high-throughput workflow based on sequential cell fractionation to profile the global proteome and phospho-proteome dynamics across six distinct subcellular fractions. We benchmark the workflow by studying spatio-temporal EGFR phospho-signaling dynamics in vitro in HeLa cells and in vivo in mouse tissues. Finally, we investigate the spatio-temporal stress signaling, revealing cellular relocation of ribosomal proteins in response to hypertonicity and muscle contraction. Proteomics data generated in this study can be explored through https://SpatialProteoDynamics.github.io

Analysis of Li-8(alpha, n)B-11 below the Coulomb barrier in the potential model

The reaction Li-8(alpha, n)B-11 is of interest in inhomogeneous big bang nucleosynthesis. A distorted wave Born approximation calculation employing folding potentials is presented for energies below the Coulomb barrier. The recently observed resonance at about 540 keV center-of-mass energy can be reproduced. The astrophysical S factor is calculated for the ground-state transition as well as for the transitions to the first four excited states of B-11. The reaction rate is derived and compared to literature data. The inclusion of the excited states increases the rate by a factor of 1.5 compared to the ground-state transition.Peer reviewe