16 research outputs found
Risk and Marginalization in the Norwegian Welfare Society: a National Cohort Study of Child Welfare Involvement
Human Rights in Child Protection Rights-Based Practice and Marginalized Children in Child Protection Work
Our point of departure in this chapter is to ask whether the avowed aim of a preventative approach in child protection, with strategies that set out to avoid the very large moral and economic costs of placement outside the family, is at all well served by the prevailing distribution of child protection assistance to families and children. And how might rights-based, professional child protection work be of help? The chapter starts with a discussion of marginalization as a prevailing empirical characteristic used to describe families in contact with child protection services (CPS). After this, the focus shifts to a discussion of the role implementation of CRC can play, with the right to education (Articles 28, 29) as a concrete focus.publishedVersion© The Author(s) 2018. This chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/
Should we take their children? Caseworkers’ negotiations of ‘good enough’ care for children living with high-conflict parents
Aerial medical evacuation of health workers with suspected Ebola virus disease in Guinea Conakry-interest of a negative pressure isolation pod-a case series
Norwegian Child Welfare Services: A Successful Program for Protecting and Supporting Vulnerable Children and Parents?
Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial
Abstract
The MIRACLE trial (MERS-CoV Infection tReated with A Combination of Lopinavir/ritonavir and intErferon-β1b) investigates the efficacy of a combination therapy of lopinavir/ritonavir and recombinant interferon-β1b provided with standard supportive care, compared to placebo provided with standard supportive care, in hospitalized patients with laboratory-confirmed MERS. The MIRACLE trial is designed as a recursive, two-stage, group sequential, multicenter, placebo-controlled, double-blind randomized controlled trial. The aim of this article is to describe the statistical analysis plan for the MIRACLE trial. The primary outcome is 90-day mortality. The primary analysis will follow the intention-to-treat principle. The MIRACLE trial is the first randomized controlled trial for MERS treatment.
Trial registration
ClinicalTrials.gov, NCT02845843. Registered on 27 July 2016