Characteristics of hotel premises in Belgorod city

Hotel industry is regarded as one of the factors in the development of tourism and the initial basis for planning the production of the tourist product. It determines the specificity of the development of tourism, being the basis for the production of the tourism product in planning the priorities of the investment policy. The article presents the results of the authors’s research, as well as materials open print and electronic resources. The authors analyzed the state of hotel real estate market of Belgorod, the structure of the number of rooms, hotel occupancy assessed by type of rooms, highlighted promising areas of the hotel business. It should be noted, that the development of domestic tourism, the growth of business and cultural activity in the region will contribute to the further development of tourism infrastructure and, in particular, the hotel industryyesБелгородский государственный университе

Assessment of the therapeutic efficacy of various drugs against cryptosporidiosis in calves

The purpose of the research is studying the spread of cryptosporidiosis in calves and assessment of the extenseeffectiveness of antiprotozoal drugs.Materials and methods. The spread, seasonal and age-specific trends of cryptosporidiosis was studied on 395 spontaneously infected animals of five age groups. The first group was formed of calves up to 10 days of age, the second group of calves aged from 11 days to 2 months, the third group of calves from 2 to 4 months, the fourth group of calves from 4 to 6 months of age, and the fifth group of young animals from 6 months up to 1 year. To assess the efficacy of various drugs against cryptosporidiosis in calves, 5 groups of infected animals (4 experimental and 1 control), 10 animals each, were formed according to the principle of analogous pairs. The infection rate in cattle was determined by generally accepted coprological flotation methods, as well as by native smears with further staining according to Ziehl-Nielsen. We also considered clinical signs of cryptosporidiosis (diarrhea, dehydration).Results and discussion. We established the widespread occurrence of cryptosporidiosis in cattle on the farms of the Igrinsky, Uvinsky, Zavyalovsky Districts of the Udmurt Republic. The infection rate ranged from 20.25 to 80.0%. The largest percentage of infected calves was observed in the winter-spring period which was associated with the synchronization of the reproductive cycles of cows and a decrease in the resistance of the animal organism. Toltarox 5% and Galokur drugs in work environments showed 100% extense-effectiveness. It is not recommended to apply Amprolium 25% on these farms due to the low efficacy and the development of parasite resistance to this drug

The influence of virtual information spaces on tourism development

The desire to meet the requirements of the consumer necessitates the study of the influence of modern information and communication technologies on the development of the tourism industry by operators. The urgency of creating a virtual tourist information system, and developing its structure is required in order to match the innovative processes that involve modern technologies of Virtual and Augmented Realit

Scanning Electron Microscopy Study of Drilling Cuttings in Tomsk Oblast Sites

The research is focused on determining mineralogical composition of drilling cuttings by scanning electron microscope as well as imaging the sample surface of high resolution that allows studying the structural characteristics of the site. In addition, a number of other techniques permit obtaining information on chemical composition of sample in near-surface layers. The study in drilling cuttings by means of scanning microscopy has revealed the presence of titanium, iron, zirconium oxides, iron sulphide, barium sulphate. The former is a mineral that concentrates rare-earth elements, presumably monocyte, as well as uranium silicate, etc. The results obtained confirm the data of previous X-ray structural analysis, i.e. the study samples consist of alumosilicate matrix. Apart from silicon and aluminium oxides, the matrix includes such elements as Na, K, Mg. Such a composition corresponds to rock-forming minerals: quartz, albite, microcline, clinochlore, muscovite, anorthoclase

Study of value orientations among russian students

The study substantiates the need for value orientations study among Russian college students due to the changes in economic and political foundations of Russian society. Theoretical approaches to the classification of values are considered. We considered the researchers approach to the determination of values based on the modification of the classification proposed by M. Rokeac

Morphofunctional state of a heart left ventricles of patients who have primary hypothyroidism

The examination and estimation of structural and functional state of left heart chambers in dependence of the functional state of peripheral arteries endothelium of the patients with renal hypertension have been carried out. The examination included 80 patients with renal hypertension and 60 healthy volunteers. The patients from both groups were subjected to echocardiography and reactive hyperemia tests in order to evaluate the functional state of endothelium. Concentric remodeling was more frequently revealed in patients with renal hypertension and endothelium dysfunction. Besides, diastolic dysfunction with the affection of both the left ventricle myocardium rigidity and its active relaxation was observed more frequently in the patients with renal hypertension in presence of the endothelium dysfunction.Проведено исследование и оценка структурно-функционального состояния левых камер сердца у пациентов с ренопаренхиматозной артериальной гипертонией (РПГ) в зависимости от функционального состояния эндотелия периферических артерий. В исследование было включено 80 пациентов с РПГ и 60 пациентов контрольной группы. Пациентам обеих групп проводили зхокардиографическое исследование и пробу реактивной гиперемии для оценки функционального состояния эндотелия. У пациентов с РПГ и эндотелиальной дисфункцией достоверно чаще формировалось концентрическое ремоделирование. Кроме того, наблюдалась диастолическая дисфункция в виде нарушения активной релаксации и повышения жесткости миокарда ЛЖ в сравнении с пациентами с РПГ и нормальной функцией эндотелия периферических артерий

Plane torsion waves in quadratic gravitational theories

The definition of the Riemann-Cartan space of the plane wave type is given. The condition under which the torsion plane waves exist is found. It is expressed in the form of the restriction imposed on the coupling constants of the 10-parametric quadratic gravitational Lagrangian. In the mathematical appendix the formula for commutator of the variation operator and Hodge operator is proved. This formula is applied for the variational procedure when the gravitational field equations are obtained in terms of the exterior differential forms.Comment: 3 May 1998. - 11

Оценка чувствительности и специфичности ASAS-критериев для периферического спондилоартрита у пациентов с ранним псориатическим артритом

Objective: to estimate the sensitivity and specificity of ASAS (Assessment of Spondyloarthritis International Society) criteria for peripheral spondyloarthritis (SpA) in patients with early psoriatic arthritis (ePsA).Subjects and methods. Examinations was made in 45 patients (17 men and 28 women) with ePsA meeting the CASPAR (ClASsification criteria for Psoriatic ARthritis) criteria (mean age, 37 years; disease duration, 1 year) and in 20 patients (9 men and 11 women) with signs of peripheral SpA meeting the ESSG (European Spondyloarthropathy Study Group) criteria (mean age, 23 years; disease duration, 2.25 years; control group). The investigators estimated 78/76 tender/swollen joints and enthuses using MASES (Maastricht Ankylosing Spondylitis Enthesitis Score) and assessed the presence of inflammatory spinal pain according to the ASAS criteria, psoriasis, uveitis, inflammatory bowel diseases, genitourinary and/or enteric infections, and a family history of SpA. They also performed X-ray studies of the hand and distal portions of the foot and pelvis and graded sacroilitis using the Kellgren scores. HLA-B27, C-reactive protein, and erythrocyte sedimentation rate were determined. The sensitivity/specificity, likelihood ratios, and clinical value of criteria were calculated.Results. 41/4 and 31/14 patents with ePsA met/unmet Criteria Sets I and II. The sensitivity/specificity of Sets I and II was 91.1/10% and 68.8/95%, respectively. One patient with ePsA and two patients in the control group did not meet one of the sing sets. The total sensitivity/specificity was 97.8/10%. In the control group, the sensitivity/specificity of Sets I and II was 91.1/100% and 68.8/100%, respectively. For ePsA, the positive likelihood ratio proved to be high for Set II (13.78%) and low for Set I (1.01).Conclusion. ASAS Criteria Set I for peripheral SpA is of low value in identifying ePsA and Sign Set II shows a high value in diagnosing ePsA as it includes the major clinical manifestations of the disease. Both the ASAS for peripheral SpA and CASPAR criteria may be used for the classification of PsA.Цель исследования – определение чувствительности и специфичности критериев ASAS (Assesment of Spondyloarthriitis International Society) для периферического спондилоартрита (СпА) при раннем псориатическом артрите (рПсА).Материал и методы. Обследовано 45 больных (17 мужчин и 28 женщин) с рПсА, соответствующих критериям CASPAR (ClASsification criteria for Psoriatic ARthritis), средний возраст – 37 лет, длительность заболевания – 1 год и 20 больных (9 мужчин и 11 женщин) с признаками периферического СпА, соответствующих критериям ESSG (European Spondyloarthropathy Study Group), средний возраст – 23 года, длительность заболевания – 2,25 года (контрольная группа). Оценивали 78/76 болезненных/припухших суставов, энтезисы по MASES (Maastricht Ankylosing Spondylitis Enthesitis Score), наличие воспалительной боли в позвоночнике по критериям ASAS, псориаза, увеита, воспалительных заболеваний кишечника, мочеполовой и/или кишечной инфекции, семейный анамнез по СпА. Выполняли рентгенографию кистей, дистальных отделов стоп и таза, стадию сакроилиита оценивали по Kellgren. Опреде- ляли HLA-B27, СРБ, СОЭ. Рассчитывали чувствительность/специфичность, отношение правдоподобия результатов, клиническую значимость критериев.Результаты. 41/4 и 31/14 пациентов с рПсА соответствовали/не соответствовали I и II сету критериев. Чувствительность/специфичность I сета – 91,1/10%, II сета – 68,8/95%. 1 пациент с рПсА и 2 пациента в контрольной группе не соответствовали ни одному из сетов признаков. Общая чувствительность/специфичность – 97,8/10%. В контрольной группе чувствительность/специфичность I сета составила 91,1/100%, II сета – 68,8/100%. Для рПсА отношение правдоподобия положительного результата оказалось высоким для II (13,78) и низким для I (1,01) сета признаков.Заключение. I сет признаков критериев ASAS для периферического СпА имеет низкое значение для выявления рПсА, II сет показал высокую значимость для диагностики рПсА, так как включает основные клинические проявления заболевания. Для классификации ПсА могут быть использованы как критерии ASAS для периферического СпА, так и CASPAR