969 research outputs found
Risk and Business Goal Based Security Requirement and Countermeasure Prioritization
Companies are under pressure to be in control of their assets but at the same time they must operate as efficiently as possible. This means that they aim to implement “good-enough security” but need to be able to justify their security investment plans. Currently companies achieve this by means of checklist-based security assessments, but these methods are a way to achieve consensus without being able to provide justifications of countermeasures in terms of business goals. But such justifications are needed to operate securely and effectively in networked businesses. In this paper, we first compare a Risk-Based Requirements Prioritization method (RiskREP) with some requirements engineering and risk assessment methods based on their requirements elicitation and prioritization properties. RiskREP extends misuse case-based requirements engineering methods with IT architecture-based risk assessment and countermeasure definition and prioritization. Then, we present how RiskREP prioritizes countermeasures by linking business goals to countermeasure specification. Prioritizing countermeasures based on business goals is especially important to provide the stakeholders with structured arguments for choosing a set of countermeasures to implement. We illustrate RiskREP and how it prioritizes the countermeasures it elicits by an application to an action case
A prospective study on the role of immunotherapy in metastatic cancer patients at Combined Military Hospital Dhaka
Background: Immunotherapy is a treatment that uses a person’s immune system to fight cancer. Immunotherapy can boost or change how the immune system works so it can find and attack cancer cells. Among several cancers, metastatic cancer causes high mortality, and immunotherapies are expected to be effective in the prevention and treatment of metastatic cancer patients. In Bangladesh, we do have not enough research-based information regarding the role of immunotherapy in treating metastatic cancer patients. This study aimed to assess the role of immunotherapy in treating metastatic cancer patients.
Methods:Â This prospective observational study was conducted in combined military hospital Dhaka, Bangladesh during the period from 26 March 2021 to 21 July 2022. In total 19 patients with metastatic cancer were enrolled in this study as study subjects. Proper written consent was taken from all the participants before data collection. Two (02) different outcomes were studied in this study; progression-free survival (PFS) and side effect percentages. A predesigned questionnaire was used in data collection. All data were processed, analyzed, and disseminated by using MS excel and SPSS version 23 program as per necessity.
Results: In using pembrolizumab, side effects, fatigue, nausea, and decreased appetite were found 43%, 22%, and 20% lesser respectively than chemotherapy which was noticeable. In using nivolumab, as a side effect, skin rash was found 66% lesser than chemotherapy. Besides this, itching, face swelling, and apnea was found 33% lesser. On the other hand, in using atezolizumab, as side effects, swelling of arms and constipation were found 66% lesser, and itching, as well as apnea, was found 33% lesser than that in chemotherapy. At the 6-month follow-up we observed that in the nivolumab and atezolizumab treated groups 66% of cases survived separately whereas, in pembrolizumab treated group, 61% survived.
Conclusions:Â In this study in all treatment groups, side effects were found as lesser than that in using chemotherapy. No major complication of any patients was observed in this study. So, can conclude that immune checkpoint inhibitors (ICIs) are better choice for metastatic diseases and ICIs exert lesser side effects than conventional chemotherapies
HIV Infection and Compromised Mucosal Immunity: Oral Manifestations and Systemic Inflammation
Increasing farm income by introducing fish culture in deepwater rice environment
Fish culture in deep-water-rice (DWR) environment using net pen and polder systems was evaluated. In net pen rohu and Thai silver barb were cultured, whereas a 5-species combination (rohu, mrigal, common carp, grass carp and Thai silver barb) were cultured with BR3 rice variety and DWR. Boro-fish production system produced 2.8 t/ha of fish and 7.33 t/ha of rice in polder system with 5-species combinations
Growth and production of Nile tilapia (Oreochromis niloticus Lin.) in irrigated Boro rice under floodplain environment
The experiment was conducted at BRRI Regional Station, Habiganj during 1994-95 to evaluate the growth and economic performance of Nile tilapia, Oreochromis niloticus, fish reared in the field of irrigated boro rice with different fertilizer levels. Grain yield of rice was not affected by fish culture. It was observed that 50% of recommended fertilizer was enough to produce increased rice yield (8-10 t/ha) at floodplain environment and additional yield was obtained with the increasing fertilizer rates. Results further indicated that O. niloticus could successfully be reared in the field of irrigated boro rice with recommended fertilizer level. Larger size of fingerlings at release had improved recovery percent, body weight gain and higher fish yield. Results also revealed that rice + fish production system produced higher net return than the system with rice alone
Application of poloidal beta and plasma internal inductance in determination of input power time of Damavand tokamak
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