Association between alcohol consumption and one-carbon metabolite intake and the risk of liver cancer incidence and liver disease mortality in the ATBC Study.

*<p>adjusted for age, education,smoking, BMI, diabetes and study arm</p

Distribution of select baseline characteristics across total one-carbon metabolite intake tertiles and alcohol consumption in the ATBC Study.

<p>Distribution of select baseline characteristics across total one-carbon metabolite intake tertiles and alcohol consumption in the ATBC Study.</p

Association between alcohol consumption and one-carbon metabolite serum levels and the risk of liver cancer incidence in the ATBC Study.

*<p>adjusted for age,education, smoking, BMI, diabetes, study arm, HBV, HCV</p

Proportion of PPI use, <i>H. pylori</i> infection and fundic atrophy among categories generated by G-17 cutoff values.

<p>G-17: gastrin-17, PPI: proton pump inhibitor, IQR: interquartile range.</p><p>*Fundic atrophy was defined by histology gold standard.</p

Screening characteristics of PGI and PGI/PGII ratio for diagnosis of fundic atrophy and nonatrophic pangastritis.

<p>CI: confidence interval, AUC: area under curve, PPV: positive predictive value, NPV: negative predictive value, PGI: pepsinogen I, PGII: pepsinogen II, G-17: gastrin-17.</p

Levels of pepsinogens, gastrin, and percentage of subjects seropositive for <i>H. pylori</i>, and CagA according to the topography of moderate/marked gastritis and atrophy.

<p>SD: Standard deviation, IQR: interquartile range, PGI: pepsinogen I, PGII: pepsinogen II, CagA: cytotoxin-associated gene A, PPI (proton pump inhibitor).</p><p>*<i>H. pylori</i> status was determined according to the results of histology examination, ELISA IgA/IgG, and Western blot.</p

AUCs for discrimination of fundic atrophy (dark bar), and nonatrophic pangastritis (dotted bar represents the study population after exclusion of fundic atrophy from reference group, diagonal lined bar represents whole study population).

<p>AUC: Area under curve, PGI: pepsinogen I, PGII. pepsinogen II, PGI/PGII ratio: pepsinogen I/pepsinogen II ratio, G-17: gastrin-17.</p