5 research outputs found
Thermal effects of carbonated hydroxyapatite modified by glycine and albumin
In this work calcium phosphate powders were obtained by precipitation method from simulated solutions of synovial fluid containing glycine and albumin. X-ray diffraction and IR spectroscopy determined that all samples are single-phase and are presented by carbonate containing hydroxyapatite (CHA). The thermograms of solid phases of CHA were obtained and analyzed; five stages of transformation in the temperature range of 25-1000Β°C were marked. It is shown that in this temperature range dehydration, decarboxylation and thermal degradation of amino acid and protein connected to the surface of solid phase occur. The tendency of temperature lowering of the decomposition of powders synthesized from a medium containing organic substances was determined. Results demonstrate a direct dependence between the concentration of the amino acid in a model solution and its content in the solid phase
ΠΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡ Π΄Π΅ΠΉΡΡΠ²ΠΈΠΉ ΠΏΡΠΈ Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΊΡΠΎΠ²ΠΎΠΈΠ·Π»ΠΈΡΠ½ΠΈΠΉ/Π³Π΅ΠΌΠ°ΡΠΎΠΌ ΠΌΡΠ³ΠΊΠΈΡ ΡΠΊΠ°Π½Π΅ΠΉ Ρ ΠΏΠΎΠΆΠΈΠ»ΡΡ Π±ΠΎΠ»ΡΠ½ΡΡ , ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ SARS-CoV-2
Aim. To determine ultrasound, computed tomography and angiographic image characteristics for soft tissue hemorrhages/hematomas, the sequence of using imaging methods in patients infected with SARS-CoV-2, to study the morphology of changes in soft tissues, to determine the essence of the concept and to develop treatment tactics for this complication of COVID-19.Material and methods. During 4 months of treatment of elderly patients (+60) infected with SARS-CoV-2, 40 patients were identified with soft tissue hemorrhages/hematomas, of which 26 (65%) patients with large hematomas (>10 cm in size and > 1000 ml in volume). The analysis of clinical and laboratory parameters, methods of instrumental diagnostics (ultrasound β 26 patients, CT β 10 patients, angiography β 9 patients, punctures β 6 patients) was carried out; autopsy material was studied in 11 cases.Results. Image characteristics of hemorrhages/hematomas of soft tissue density were obtained using modern instrumental methods, and the sequence of application of visualization methods was determined. A tactic for managing a patient with stopped and ongoing bleeding has been developed. The morphological substrate of hemorrhagic complications in a new viral infection was studied. All patients were treated with conservative and minimally invasive procedures (embolization, puncture with pressure bandage). 15 patients (57.7%) recovered, 11 patients (42.3%) died from the progression of COVID-19 complications.Conclusion. Comprehensive clinical and laboratory sequential instrumental diagnosis of soft tissue hemorrhages in COVID-19. Treatment should be conservative and significantly invasive. The use of the term βsoft tissue hematomaβ in SARS-CoV-2 infected patients is not a natural quality of the normal pathological process and should not be observed from our point of view.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: ΠΎΠΏΡΠ΅Π΄Π΅Π»ΠΈΡΡ Π²ΠΈΠ·ΡΠ°Π»ΡΠ½ΡΠ΅ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΡΠ΅, ΠΊΠΎΠΌΠΏΡΡΡΠ΅ΡΠ½ΠΎ-ΡΠΎΠΌΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈ Π°Π½Π³ΠΈΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΊΡΠΈΡΠ΅ΡΠΈΠΈ ΠΌΡΠ³ΠΊΠΎΡΠΊΠ°Π½Π½ΡΡ
ΠΊΡΠΎΠ²ΠΎΠΈΠ·Π»ΠΈΡΠ½ΠΈΠΉ/Π³Π΅ΠΌΠ°ΡΠΎΠΌ, ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
, ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
SARS-CoV-2, ΠΈΠ·ΡΡΠΈΡΡ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Π² ΠΌΡΠ³ΠΊΠΈΡ
ΡΠΊΠ°Π½ΡΡ
, ΠΎΠΏΡΠ΅Π΄Π΅Π»ΠΈΡΡ ΡΡΡΡ ΠΏΠΎΠ½ΡΡΠΈΡ ΠΈ Π²ΡΡΠ°Π±ΠΎΡΠ°ΡΡ Π»Π΅ΡΠ΅Π±Π½ΡΡ ΡΠ°ΠΊΡΠΈΠΊΡ ΠΏΡΠΈ ΡΠ°ΠΊΠΎΠΌ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΈ COVID-19.ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΠ° 4 ΠΌΠ΅Ρ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠΎΠΆΠΈΠ»ΡΡ
Π±ΠΎΠ»ΡΠ½ΡΡ
(+60), ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
SARS-CoV-2, Π²ΡΡΠ²Π»Π΅Π½ΠΎ 40 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΌΡΠ³ΠΊΠΎΡΠΊΠ°Π½Π½ΡΠΌΠΈ ΠΊΡΠΎΠ²ΠΎΠΈΠ·Π»ΠΈΡΠ½ΠΈΡΠΌΠΈ/Π³Π΅ΠΌΠ°ΡΠΎΠΌΠ°ΠΌΠΈ, ΠΈΠ· Π½ΠΈΡ
26 (65%) ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π±ΠΎΠ»ΡΡΠΈΠΌΠΈ Π³Π΅ΠΌΠ°ΡΠΎΠΌΠ°ΠΌΠΈ (ΡΠ°Π·ΠΌΠ΅Ρ >10 ΡΠΌ ΠΈ ΠΎΠ±ΡΠ΅ΠΌ> 1000 ΠΌΠ»). ΠΡΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΎ-Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ, ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ (Π£ΠΠ β 26 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΠΠ’ β 10 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², Π°Π½Π³ΠΈΠΎΠ³ΡΠ°ΡΠΈΡ β 9 Π±ΠΎΠ»ΡΠ½ΡΡ
, ΠΏΡΠ½ΠΊΡΠΈΠΈ β 6 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ²), Π² 11 ΡΠ»ΡΡΠ°ΡΡ
ΠΈΠ·ΡΡΠ΅Π½ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π» Π°ΡΡΠΎΠΏΡΠΈΠΈ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π‘ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠΌΠΈ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ ΠΏΠΎΠ»ΡΡΠ΅Π½Π° Π²ΠΈΠ·ΡΠ°Π»ΡΠ½Π°Ρ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ° ΠΊΡΠΎΠ²ΠΎ ΠΈΠ·Π»ΠΈΡΠ½ΠΈΠΉ/Π³Π΅ΠΌΠ°ΡΠΎΠΌ ΠΌΡΠ³ΠΊΠΎΡΠΊΠ°Π½Π½ΠΎΠΉ ΠΏΠ»ΠΎΡΠ½ΠΎΡΡΠΈ, ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π° ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΡΡΡ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ. Π Π°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π° ΡΠ°ΠΊΡΠΈΠΊΠ° Π²Π΅Π΄Π΅Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° ΠΏΡΠΈ ΠΎΡΡΠ°Π½ΠΎΠ²ΠΈΠ²ΡΠ΅ΠΌΡΡ ΠΈ ΠΏΡΠΎΠ΄ΠΎΠ»ΠΆΠ°ΡΡΠ΅ΠΌΡΡ ΠΊΡΠΎΠ²ΠΎΡΠ΅ΡΠ΅Π½ΠΈΠΈ. ΠΠ·ΡΡΠ΅Π½ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΡΠ±ΡΡΡΠ°Ρ Π³Π΅ΠΌΠΎΡΡΠ°Π³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΡ ΠΏΡΠΈ Π½ΠΎΠ²ΠΎΠΉ Π²ΠΈΡΡΡΠ½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ. ΠΡΠ΅ Π±ΠΎΠ»ΡΠ½ΡΠ΅ ΠΏΡΠΎΠ»Π΅ΡΠ΅Π½Ρ ΠΊΠΎΠ½ΡΠ΅ΡΠ²Π°ΡΠΈΠ²Π½ΡΠΌΠΈ ΠΈ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎ ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΡΠΌΠΈ ΠΏΡΠΎΡΠ΅Π΄ΡΡΠ°ΠΌΠΈ (ΡΠΌΠ±ΠΎΠ»ΠΈΠ·Π°ΡΠΈΡ, ΠΏΡΠ½ΠΊΡΠΈΡ Ρ Π΄Π°Π²ΡΡΠ΅ΠΉ ΠΏΠΎΠ²ΡΠ·ΠΊΠΎΠΉ). ΠΡΠ·Π΄ΠΎΡΠΎΠ²Π΅Π»ΠΈ 15 (57,7%) ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΡΠΌΠ΅ΡΠ»ΠΈ ΠΎΡ ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ COVID-19 11 (42,3%) Π±ΠΎΠ»ΡΠ½ΡΡ
.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½Π°Ρ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΎ-Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½Π°Ρ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½Π°Ρ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΠ°Π»ΡΠ½Π°Ρ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ° ΠΌΡΠ³ΠΊΠΎΡΠΊΠ°Π½Π½ΡΡ
ΠΊΡΠΎΠ²ΠΎΠΈΠ·Π»ΠΈΡΠ½ΠΈΠΉ ΠΏΡΠΈ COVID-19-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΈ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΡΠ²ΠΎΠ΅Π²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎ ΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ ΡΠΎΠΏΠΈΡΠ΅ΡΠΊΠΈΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΠ·, ΠΎΡΠ΅Π½ΠΈΡΡ ΡΡΠΆΠ΅ΡΡΡ ΠΊΡΠΎΠ²ΠΎΠΏΠΎΡΠ΅ΡΠΈ, Π΅Π΅ ΠΎΡΡΠ°Π½ΠΎΠ²ΠΊΡ ΠΈΠ»ΠΈ ΠΏΡΠΎΠ΄ΠΎΠ»ΠΆΠ΅Π½ΠΈΠ΅ ΠΊΡΠΎΠ²ΠΎΡΠ΅ΡΠ΅Π½ΠΈΡ. ΠΠ΅ΡΠ΅Π½ΠΈΠ΅ Π΄ΠΎΠ»ΠΆΠ½ΠΎ Π½ΠΎΡΠΈΡΡ ΠΊΠΎΠ½ΡΠ΅ΡΠ²Π°ΡΠΈΠ²Π½ΡΠΉ ΠΈ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎ ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΡΠΉ Ρ
Π°ΡΠ°ΠΊΡΠ΅Ρ. ΠΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅ΡΠΌΠΈΠ½Π° βΠ³Π΅ΠΌΠ°ΡΠΎΠΌΠ°β ΠΌΡΠ³ΠΊΠΈΡ
ΡΠΊΠ°Π½Π΅ΠΉ Ρ ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
SARS-CoV-2 Π±ΠΎΠ»ΡΠ½ΡΡ
Π½Π΅ ΠΎΡΡΠ°ΠΆΠ°Π΅Ρ ΡΡΡΡ ΠΏΡΠΎΠΈΡΡ
ΠΎΠ΄ΡΡΠ΅Π³ΠΎ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° ΠΈ, Ρ Π½Π°ΡΠ΅ΠΉ ΡΠΎΡΠΊΠΈ Π·ΡΠ΅Π½ΠΈΡ, Π½Π΅ Π΄ΠΎΠ»ΠΆΠ½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡΡΡ
Structure, development, and evolutive patterns of spermatozoa in rhabditid nematodes (Nematoda: Rhabditida)
Spermatogenesis of five rhabditid nematodes was studied using transmission electron microscopy and is described herein. Structure and development of nematode sperm in all available representatives of the extensive order Rhabditida have been analysed and the main characteristics of each infraorder are discussed. The ancestral sperm of the order Rhabditida was reconstructed using maximum likelihood and Bayesian methods based on 44 ultrastructural sperm characters. The hypothetical ancestral spermatogenesis of the order Rhabditida agrees with the previously suggested "rhabditid" pattern and appears to be conserved throughout the order Rhabditida. Despite the enormous variation of rhabditid nematodes, few groups deviate from the ancestral pattern. This conserved pattern can be informative within the phylum Nematoda at order level, but poses limitations when used in taxonomic and phylogenetic analysis within Rhabditida