Primary follicular and marginal-zone lymphoma of the breast: clinical features, prognostic factors and outcome: a study by the International Extranodal Lymphoma Study Group

Background: Primary breast lymphoma (PBL) of low-grade histology is a rare disease. This multicentric retrospective study was carried out to determine clinical features, prognosis and relapse. Patients and methods: Patients with histologically proven, previously untreated follicular or marginal-zone PBL (MZL PBL) diagnosed from 1980 to 2003 were included in the study. Major end points were progression-free survival (PFS), overall survival (OS) and potential prognostic factors. Results: We collected data on 60 cases of PBL [36 follicular and 24 marginal-zone lymphoma (MZL)]. Stage was IE or IIE in 57 patients and IVE in three patients due to bilateral breast involvement. Surgery, chemotherapy and radiotherapy (RT), alone or in combination, were used as first-line treatments in 67%, 42% and 52% of patients, respectively. Overall response rate was 98%, with a 93% complete response rate. Five-year PFS were 56% for MZL and 49% for follicular PBL (P = 0.62). Relapses were mostly in distant sites (18 of 23 cases); no patients relapsed within RT fields. Conclusions: Our data showed an indolent behaviour of MZL PBL, comparable to other primary extranodal MZL. Conversely, patients with follicular PBL had inferior PFS and OS when compared with limited-stage nodal follicular non-Hodgkin's lymphomas, suggesting an adverse prognostic role of primary breast localisation in this histological subgrou

Territori e pratiche di convivenza interetnica

L’esito di ricerche empiriche e riflessioni teoriche sul tema della convivenza interetnica nei contesti urbani in Italia. Le analisi proposte nel libro raffigurano un viaggio sociologico e antropologico assai significativo del cambiamento in atto nelle nostre città e delle possibilità che si offrono per favorire politiche d’integrazione a livello locale

Nuove tecnologie nelle scuole superiori dell'Emilia Romagna.

Il capitolo presenta premesse e ipotesi di una ricerca sulla socializzazione alle nuove tecnologie presso le scuole superiori dell'Emilia Romagna. Attraverso l'invio di questionari a docenti responsabili di progetti di educazione alla salute e all'ambiente, a dirigenti e a docenti referenti per le nuove tecnologie, si è cercato di ricostruire un quadro del cambiamento scolastico della regione, tra riforme autonomistiche e utilizzo delle tecnologie. Si sono inoltre analizzati i siti web prodotti dalle scuole, un campione di Pof (Piani dell'offerta formativa) e sono stati raccolti dati relativi alle dotazioni tecnologiche delle scuole

Distorsioni medie reali nel foglio tetraedrico delle miche

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THE CRYSTAL-STRUCTURE AND CHEMISTRY OF HIGH-ALUMINUM PHLOGOPITE

Crystal structure refinements were performed on five Al-rich phlogopite-1M crystals (1.50 less than or equal to Al3+ less than or equal to 1.97 atoms per formula unit) from skarns of the Predazzo and Monzoni Hills petrographic area (north-east Italy) with the aim of characterizing geometrical variation produced by Al3+ increase. The charge imbalance was mostly compensated for by substitutions of highly charged cations in the octahedral sheet (Al3+ and/or Fe3+ for Mg2+). The refinements were carried out in the mean space group C2/m and gave agreement values (R) between 0.025 and 0.030. For some additional crystals, only chemistry and/or unit cell parameters were determined. In all samples the tetrahedra are more regular and larger than those previously reported in the literature for phlogopite crystals and the misfit between tetrahedral and octahedral sheets, produced by the increase in the tetrahedral edges, is mostly compensated for by the tetrahedral ring angle rotation alpha (10.2 degrees less than or equal to alpha less than or equal to 12.5 degrees), whereas the octahedral sheet features seem affected only by local crystal-chemical variations

The crystal chemistry of high-aluminium phlogopite

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