The Review of Anthrax Situation 2013, the Forecast for 2014

The analysis of epidemiological and epizootiological situation on anthrax in the Russian Federation and in the world in 2013 is carried out. The forecast of disease for 2014 is presented. Anthrax morbidity in humans in Russia is shown to decrease in 2013 in comparison with that in 2012 (2 cases versus 12). Three anthrax cases are registered in cattle

ORGANIZATION OF LABORATORY RESEARCH OF CLINICAL AND ENVIRONMENTAL SAMPLES DURING THE ANTHRAX OUTBREAK IN THE YAMALO-NENETS AUTONOMOUS DISTRICT IN 2016

Presented are the order and features of organization of operative diagnostic and monitoring studies of the material during the anthrax outbreak in the Yamalo-Nenets Autonomous District in 2016. Characterized are the main directions of the laboratory base work. Represented are the results of laboratory studies of various materials (clinical samples, material from animals, samples of environmental objects) for the presence of Bacillus anthracis

BIOLOGICAL PROPERTIES AND MOLECULAR-GENETIC CHARACTERISTICS OF BACILLUS ANTHRACIS STRAINS, ISOLATED DURING THE OUTBREAK OF ANTHRAX IN THE YAMALO-NENETS AUTONOMOUS DISTRICT IN 2016

Objective of the study was to identify phenotypic properties and genetic peculiarities of Bacillus anthracis strains, isolated during the outbreak of anthrax in the territory of Yamal in 2016. Materials and methods. Investigated were the strains of anthrax agent, applying basic and subsequent identification tests and canSNP-, MLVA-genotyping methods and whole genome sequencing. Results and conclusions. The results showed the identity of the phenotypic properties, canSNPand MLVA25-genotypes, and profiles of whole genome-sequencing, regardless of the source of the strains isolation. Confirmed was a common source of human infection. Defined were phylogenetic interrelations of the tested strains and their position in global B. anthracis population. For the first time ever explored was variability of the gene pattern, associated with pathogenicity, and demonstrated – the efficiency of the proposed algorithm for genetic typing