Prompt treatment of disseminated HSV-2 infection in a patient with compromised cellular immunity: A case of aborted hemophagocytic lymphohistiocytosis?

Recognition of unusual manifestations such as disseminated HSV or HSV-related hemophagocytic lymphohistiocytosis among individuals with impaired cellular immunity and prompt treatment initiation are essential for a favorable outcome. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd

Initial and continued adherence to wearing appropriate footwear in people with diabetic foot disease: results of a pilot study

Background: For the prevention and healing of diabetic foot ulcers, appropriate footwear or medical devices are utilized. However, initial and continued adherence of patients with diabetes-related foot problems in using such therapeutic means, is not satisfactory. bjective: To explore initial and continued adherence to wearing appropriate footwear in people with diabetic foot disease. Methods: A cross-sectional study was conducted, from March to November 2016, at general and special hospitals in Athens, Greece. Forty-one outpatients with type 1 and 2 Diabetes Mellitus, with medical recommendation for wearing appropriate footwear, participated. A structured quantitative interview guide and medical measuring instruments were used. For data analysis, descriptive and inferential statistic methods were applied using the IBM SPSS 24 software package. Results: Suitable for diabetes footwear were worn from the 56.1% of participants. The 27.3% of risk patients wore their preventive shoes ≥60% (≥9.6 hours) of daytime. The patients with active foot ulcers wore appropriate footwear at a lesser percentage than the ones at risk (44.4% versus 78.6%, χ2(1) =4.36, p=0.037; OR 4.58, 95% CI 1.04-20.24, p=0.045) and the initially adherent group had significantly subordinate Visual Analogue Scale score in relation to the satisfaction from the footwear price (Mdn=5.00) than the one that was not initially adherent (Mdn=8.00), U=97.00, z=-2.36, p=0.019, r=-.38. Conclusion: For the enhancement of initial and continued adherence in wearing appropriate footwear, health care professionals could pay more attention to the education of patients with active foot ulcers, underling the importance of using right shoes. Additionally, they could provide patients with multiple price options concerning their footwear (e.g. by suggesting effective and affordable products)

Evaluating trustworthiness through monitoring: The foot, the horse and the elephant

This paper presents a framework for trust evaluation through monitoring, in particular, to address the question of how to derive trust from observations of certain properties. We propose a trust model based on subjective logic to represent trust through the notion of an opinion and to include aspects of uncertainty in a systematic fashion. Moreover, we analyze requirements for opinion generators and introduce novel parameterized generators that capture the requirements for opinion generators much better than current generators do. In addition, we show how a decision can be made based on trust monitoring within a certain context. The proposed trust evaluation framework is demonstrated with a case study of a Body Area Sensor Network. The results and examples show that the opinion generators can effectively work with various types of properties, including dependability, security and functionality related properties