Performance Tuning of Dual-priority Delta Networks through Queuing Scheduling Disciplines

Differentiated Services (DiffServ) and other scheduling strategies are now widespread in the traditional, “best effort” Internet. These Internet Architectures offer Quality of Service (QoS) guarantees for important customers at the same time as supporting less critical applications of lower priority. Strict priority queuing (PQ), weighted round robin (WRR), and class-based weighted fair queuing (CBWFQ) are three common scheduling disciplines for differentiation of services in telecommunication networks. In this paper, a comparative performance study of the above PQ, WRR and CBWFQ queuing scheduling policies applied on a double-buffered, 6-stage Multistage Interconnection Network (MIN) that natively supports a 2-class priority mechanism is presented and analyzed using simulation experiments. We also consider a 10-stage MIN, to validate that the conclusions drawn from the 6-stage MIN apply to MINs of different sizes. The findings of this paper can be used by MIN designers to optimally configure their networks

Estimation of the stress related to conservative scoliosis therapy: an analysis based on BSSQ questionnaires

BACKGROUND: Adolescent girls treated with a brace for scoliosis are submitted to prolonged stress related to both the disease and the therapy. Currently proposed quality of life questionnaires are focused on the outcome of therapy. Bad Sobernheim Stress Questionnaire (BSSQ) enables monitoring of patients being under treatment with a brace or exercises. The aim of the study was to assess the stress level in conservatively managed scoliotic girls using BSSQ. MATERIALS AND METHODS: 111 girls, aged 14,2 ± 2,2 years, mean Cobb angle of the primary curve 42,8° ± 17,0° and mean Bunnell angle of 11,4° ± 4,5° were examined with two versions of BSSQ (Deformity and Brace). The analysis considered the type of treatment, curve location, correlation of the total score with age, Cobb angle and Bunnell rotation angle. RESULTS: The BSSQ Deformity revealed the median of 17 points in patients managed with exercises (from 4 to 24 points), 18 in patients managed with a brace (from 8 to 24 points) and 12 in patients before surgery (from 3 to 21 points). Braced patients who completed both questionnaires (n = 50) revealed significantly higher score with BSSQ Deformity (median = 18) comparing to BSSQ Brace (median = 9). There was a correlation between the total score of BSSQ Deformity and the Cobb angle (r = -0,34), Bunnell primary curve rotation (r = -0,34) and Bunnell sum of rotation (r = -0,33) but not with the age of patients. CONCLUSION: Scoliotic adolescents managed with exercises and brace suffered little stress from the deformity. The brace increased the level of stress over the stress induced by the deformity. The stress level correlated with clinical deformity (Bunnell angle), radiological deformity (Cobb angle) and the type of treatment (exercises, bracing, surgery). Bad Sobernheim Stress Questionnaires are simple and helpful in the management of girls treated conservatively for idiopathic scoliosis

Συσχέτιση Σεισμικών Παραμέτρων και Ολικών Δεικτών Βλάβης σε Κατασκευές Οπλισμένου Σκυροδέματος

In the present work, a correlation is made between seismic intensity parameters and total damage indicators of reinforced concrete structures. For this purpose, natural ground motions recordings were used, from which intensity measures were calculated and alternatives were proposed. Then, through dynamic inelastic time history analyzes, damage indices were evaluated for 1st and 2nd order theory (P-Delta effects). The correlation between each seismic parameter and the corresponding damage index was made through polynomial regressions. Seismic parameters that do not take into account the characteristics of the building, showed a minimal or moderate correlation, while spectral parameters of velocities and energies explain the change of damage indices in percentages above 80 or even 90 per cent.Στην παρούσα εργασία πραγματοποιείται συσχέτιση μεταξύ σεισμικών παραμέτρων έντα-σης και ολικών δεικτών βλάβης σε κατασκευές οπλισμένου σκυροδέματος. Για αυτόν τον σκοπό, χρησιμοποιήθηκαν καταγραφές πραγματικών σεισμών, από τις οποίες υπολογίστηκαν παράμετροι, που χαρακτηρίζουν ένα επιταχυνσιογράφημα και προτάθηκαν εναλλακτικές τους. Στη συνέχεια μέσω δυναμικών ανελαστικών αναλύσεων χρονοϊστορίας αποτιμήθηκαν δείκτες βλάβης για θεωρία 1ης και 2ης τάξης. Η συσχέτιση μεταξύ του εκάστοτε ζεύγους σεισμικής παραμέτρου και δείκτη βλάβης έγινε μέσω πολυωνυμικών παλινδρομήσεων. Σεισμικές παρά-μετροι που δεν λαμβάνουν υπόψη τους τα χαρακτηριστικά του ταλαντωτή, παρουσίασαν ελάχιστη ή μέτρια συσχέτιση, ενώ φασματικές παράμετροι ταχυτήτων και ενεργειών ερμη-νεύουν τη μεταβολή των δεικτών βλάβης σε ποσοστά άνω του 80 ή και 90 τοις εκατό

Foxp3 Expression in Liver Correlates with the Degree but Not the Cause of Inflammation

Patients with chronic viral hepatitis display increased expression of Foxp3 in liver, suggesting that Tregs expansion contributes to persistent infection. The purpose of this study was to elucidate whether the expression of Foxp3 relates not to the viral infection but to the resulting liver inflammation. Liver biopsies obtained from 69 individuals (26 chronic HBV hepatitis, 14 chronic HCV hepatitis, 11 nonalcoholic fatty liver disease, 8 autoimmune diseases, 2 methotrexate-related toxicity, and 8 controls) were examined, by qRT-PCR, for the mRNA expression of Foxp3, IL-10, TGF-β1, Fas, FasL, TRAIL, caspase-3, TNF-α, IFN-γ, and IL-1β. Significant increase of Foxp3 was observed in all disease groups compared to controls, which was positively correlated with the intensity of inflammation. The expression of the apoptosis mediators Fas, FasL, and TRAIL, but not of IL-10 and TGF-β1, was also significantly elevated. Our findings indicate that, independently of the initial inducer, liver inflammation is correlated with elevated expression of apoptosis mediators and is followed by local Treg accumulation. Further research towards the elucidation of the underlying casual relationships is required, in order to clarify whether our results signify the existence of a uniform Treg-mediated regulatory mechanism of apoptosis-induced inflammation

The relationship between quality of life and compliance to a brace protocol in adolescents with idiopathic scoliosis: a comparative study

<p>Abstract</p> <p>Background</p> <p>Corrective bracing for adolescent idiopathic scoliosis (AIS) has favourable outcomes when patients are compliant. However, bracing may be a stressful and traumatic experience and compliance with a bracing protocol is likely to be dependent upon patients' physical, emotional and social wellbeing. The Brace Questionnaire (BrQ), a recently-developed, condition-specific tool to measure quality of life (QOL) has enabled clinicians to study relationships between QOL and compliance.</p> <p>Methods</p> <p>The BrQ was administered to 31 AIS patients after a minimum of 1 year of wearing a brace. Subjects were 13–16 year old South African girls with Cobb angles of 25–40 degrees. Participants were divided into two groups according to their level of compliance with the bracing protocol. Brace Questionnaire sub- and total scores were compared between the two groups using the t-test for comparison of means.</p> <p>Results</p> <p>Twenty participants were classified as compliant and 11 as non-compliant. Mean total BrQ scores (expressed as a percentage) were 83.7 for the compliant group and 64.4 for the non-compliant group (p < 0.001), and on analysis of the 8 domains that make up the BrQ, the compliant group scored significantly higher in the 6 domains that measured vitality and social, emotional and physical functioning.</p> <p>Conclusion</p> <p>Poor compliance with a brace protocol is associated with poorer QOL, with non-compliant patients lacking vitality and functioning poorly physically, emotionally and socially. Quality of life for adolescents with idiopathic scoliosis may relate more to psychosocial coping mechanisms than to physical deformity and its consequences. It is important to establish whether remedial programmes are capable of addressing personal, group and family issues, improving QOL and promoting compliance.</p

CLort: High Throughput and Low Energy Network Intrusion Detection on IoT Devices with Embedded GPUs

While IoT is becoming widespread, cyber security of its devices is still a limiting factor where recent attacks (e.g., the Mirai bot-net) underline the need for countermeasures. One commonly-used security mechanism is a Network Intrusion Detection System (NIDS), but the processing need of NIDS has been a significant bottleneck for large dedicated machines, and a show-stopper for resource-constrained IoT devices. However, the topologies of IoT are evolving, adding intermediate nodes between the weak devices on the edges and the powerful cloud in the center. Also, the hardware of the devices is maturing, with new CPU instruction sets, caches as well as co-processors. As an example, modern single board computers, such as the Odroid XU4, come with integrated Graphics Processing Units (GPUs) that support general purpose computing. Even though using all available hardware efficiently is still an open issue, it has the promise to run NIDS more efficiently.In this work we introduce CLort, an extension to the well-known NIDS Snort that a) is designed for IoT devices b) alleviates the burden of pattern matching for intrusion detection by offloading it to the GPU. We thoroughly explain how our design is used as part of the latest release of Snort and suggest various optimizations to enable processing on the GPU. We evaluate CLort in regards to throughput, packet drops in Snort, and power consumption using publicly available traffic traces.\ua0CLort achieves up to 52% faster processing throughput than its CPU counterpart. CLort can also analyze up to 12% more packets than its CPU counterpart when sniffing a network.\ua0Finally, the experimental evaluation shows that CLort consumes up to 32% less energy than the CPU counterpart, an important consideration for IoT devices

Severe axial vertebral rotation treated with a modified Boston brace: a case report

We report the case of a 13-year-old Caucasian girl suffering from severe axial rotation of the T5 to L4 vertebrae. The patient (initially examined during a school screening study) was at first considered to be suspicious of suffering from scoliosis due to a highly positive Adam's forward bending test. However, her radiographic evaluation revealed the existence of axial rotation in 12 of her vertebrae, without inclination in the sagittal and coronal planes. After an observation period of 12 months and due to the fact that both her physical appearance and the measured vertebral rotation deteriorated, the patient was given a modified thoracolumbar Boston brace that had an immediate positive derotational effect on all but two vertebrae. Twenty four months later, the progress of the vertebral rotation(s) seems to have been halted and most affected vertebrae appear to be stabilized in their new, 'post-brace', reduced position, with better results shown when the Boston brace is worn. The patient remains under constant medical observation. The application of a modified Boston brace seems to have served well (so far) a useful purpose for reducing and stabilizing this case of severe axial vertebral rotation, providing less deformity and (possibly) offering a better final cosmetic result

Brace technology thematic series: the dynamic derotation brace

<p>Abstract</p> <p>Background</p> <p>The dynamic derotation brace (DDB) was designed in Greece in 1982, as a modification of the Boston brace. It is a custom-made, underarm spinal orthosis featuring aluminium blades set to produce derotating and anti-rotating effects on the thorax and trunk of patients with scoliosis. It is indicated for the non-operative correction of most curves, barring the very high thoracic ones, (when the apex vertebra is T5 or above). The purpose of this article is to familiarize physicians with the DDB, analyze the rationale behind its design, and present the published results of its application.</p> <p>Description & Principles</p> <p>The key feature of the DDB is the addition of the aluminium-made derotating blades posteriorly. These function as a force couple, which is added to the side forces exerted by the brace itself. Corrective forces are also directed through pads. One or more of previously proposed pathomechanical models of scoliosis may underline the corrective function of the DDB: it may act directly on the apical intervertebral disc, effecting correction through the Heuter-Volkman principle; the blades may produce an anti-rotatory element against the deforming "spiral composite muscle trunk rotator"; or it may alter the neuro-motor response by constantly providing new somatosensory input to the patient.</p> <p>Results</p> <p>Based on measurements of the Cobb and Perdriolle angles, up to 82% of patients remained stable or improved with the use of the DDB. Results have varied, though, depending on the type/location of the deformity. The overall results showed that 35% of the curves improved, 46% remained stable and 18% became worse, as assessed by measuring the Cobb angle. The DDB has also been shown to improve cosmesis (except for right thoracic curves) and leave several aspects of patient quality of life unaffected during use.</p> <p>Conclusion</p> <p>Conservative treatment of idiopathic scoliosis using the DDB has shown favorable results. Thoracic curves appear more resistant to both angular and rotatory correction. The published outcome data on the DDB support our belief that the incorporation of aluminium blades to other orthoses would likely improve their efficacy.</p