Deep peri-implantitis: Two cases treated with implant apicoectomy with follow-up of at least 7 years

Aim: Deep periimplantitis is a lesion located in the periapical region of an osseointegtated implant. The aim of this study was to present 2 cases of this feature treated with apicoectomy. Materials and methods: Two cases of deep periimplantitis located in the maxillary premolar region are presented in this report. Both the lesions were situated in the apical segment of otherwise osseointegrated and long (15mm) implants. They were treated with surgical debridement, apicoectomy, bone substitute and antibiotics. Results: Bone overheating, proximity to periapical lesions or previous inflammation seem to be the three possible causes of the lesions in the cases presented. The follow-up period of 7 and 10 years indicates that implant apicoectomy is a safe and reliable treatment choice. Conclusions: The treatment of choice for deep periimplantitis is implant apicoectomy, unless the implant is mobile, where implant removal is preferable. © 2015 The British Association of Oral Surgeons and John Wiley & Sons Ltd

The influence of alendronate on osseointegration of nanotreated dental implants in New Zealand rabbits

Objectives: Growing clinical demands for stronger and faster bone bonding to the implant have motivated the development of methods enhancing osseointegration. Lately, the application of bisphosphonates (bis) in order to optimize bone healing has become a topic of great interest. N-containing bis, such as alendronate (ALN), are the more potent drugs of this class. It was the aim of this study to determine the effect of ALN on the osseointegration of a well-documented nanotreated implant system in a rabbit femoral condyle model. Material and methods: Thirty-two adult female New Zealand White rabbits received one implant (3.25mm in diameter and 10mm in length) in their left femoral condyle, a week after they were ovariectomized. Half of them were saline treated (control, group A) and the other half were ALN treated (group B). Rabbits from both groups were euthanized after 6 and 12 weeks, respectively. Results: The specimens were evaluated histologically and histomorphometrically. Upon histological evaluation, no obvious differences were found between the control and the treatment group. Implants showed good integration into the bone tissue surrounding them. There were also no statistically significant differences in bone-to-implant contact and the amount of bone tissue in the immediate neighborhood of the implant at both healing periods. Conclusions: The systemic administration of ALN was not found to affect histological osseointegration of implants in animals with a hormonal status resembling that of postmenopausal healthy women. Further research will be needed to investigate this approach. © 2011 John Wiley & Sons A/S