The development and appraisal of vocational conference in a senior high school

Thesis (M.A.)--Boston University, 1949. This item was digitized by the Internet Archive

Why do we need a theory of implementation?

The received view of computation is methodologically bifurcated: it offers different accounts of computation in the mathematical and physical cases. But little in the way of argument has been given for this approach. This paper rectifies the situation by arguing that the alternative, a unified account, is untenable. Furthermore, once these issues are brought into sharper relief we can see that work remains to be done to illuminate the relationship between physical and mathematical computation

Implementation as Resemblance

This paper advertises a new account of computational implementation. According to the resemblance account, implementation is a matter of resembling a computational architecture. The resemblance account departs from previous theories by denying that computational architectures are exhausted by their formal, mathematical features. Instead, they are taken to be permeated with causality, spatiotemporality, and other non-mathematical features. I argue that this approach comports well with computer scientific practice, and offers a novel response to so-called triviality arguments

Why do we need a theory of implementation?

The received view of computation is methodologically bifurcated: it offers different accounts of computation in the mathematical and physical cases. But little in the way of argument has been given for this approach. This paper rectifies the situation by arguing that the alternative, a unified account, is untenable. Furthermore, once these issues are brought into sharper relief we can see that work remains to be done to illuminate the relationship between physical and mathematical computation

Computation in Context

Unlimited pancomputationalism claims that every physical system implements every computational model simultaneously. Some philosophers argue that unlimited pancomputationalism renders implementation `trivial' or `vacuous', unsuitable for serious scientific work. A popular and natural reaction to this argument is to reject unlimited pancomputationalism. However, I argue that given certain assumptions about the nature of computational ascription, unlimited pancomputationalism does not entail that implementation is trivial. These assumptions concern the relativity and context sensitivity of computational ascription. Very roughly: relative to a specific, contextually salient way of regarding a physical system computationally, the claim that that system implements a specific computational model is as non-trivial as one could reasonably want

Brillouin light scattering study of Co2_{2}Cr0.6_{0.6}Fe0.4_{0.4}Al and Co2_{2}FeAl Heusler compounds

The thermal magnonic spectra of Co$_{2}$Cr$_{0.6}$Fe$_{0.4}$Al (CCFA) and Co$_2$FeAl were investigated using Brillouin light scattering spectroscopy (BLS). For CCFA, the exchange constant A (exchange stiffness D) is found to be 0.48 $\mu$erg/cm (203 meV A$^2$), while for Co$_2$FeAl the corresponding values of 1.55 $\mu$erg/cm (370 meV A$^2$) were found. The observed asymmetry in the BLS spectra between the Stokes and anti-Stokes frequencies was assigned to an interplay between the asymmetrical profiles of hybridized Damon-Esbach and perpendicular standing spin-wave modes, combined with the optical sensitivity of the BLS signal to the upper side of the CCFA or Co$_2$FeAl film

Hypoxia Activates a Ca-Permeable Cation Conductance Sensitive to Carbon Monoxide and to GsMTx-4 in Human and Mouse Sickle Erythrocytes

Background: Deoxygenation of sickle erythrocytes activates a cation permeability of unknown molecular identity (Psickle), leading to elevated intracellular [Ca2+] ([Ca2+]i) and subsequent activation of KCa 3.1. The resulting erythrocyte volume decrease elevates intracellular hemoglobin S (HbSS) concentration, accelerates deoxygenation-induced HbSS polymerization, and increases the likelihood of cell sickling. Deoxygenation-induced currents sharing some properties of Psickle have been recorded from sickle erythrocytes in whole cell configuration. Methodology/Principal Findings: We now show by cell-attached and nystatin-permeabilized patch clamp recording from sickle erythrocytes of mouse and human that deoxygenation reversibly activates a Ca2+- and cation-permeable conductance sensitive to inhibition by Grammastola spatulata mechanotoxin-4 (GsMTx-4; 1 µM), dipyridamole (100 µM), DIDS (100 µM), and carbon monoxide (25 ppm pretreatment). Deoxygenation also elevates sickle erythrocyte [Ca2+]i, in a manner similarly inhibited by GsMTx-4 and by carbon monoxide. Normal human and mouse erythrocytes do not exhibit these responses to deoxygenation. Deoxygenation-induced elevation of [Ca2+]i in mouse sickle erythrocytes did not require KCa3.1 activity. Conclusions/Significance: The electrophysiological and fluorimetric data provide compelling evidence in sickle erythrocytes of mouse and human for a deoxygenation-induced, reversible, Ca2+-permeable cation conductance blocked by inhibition of HbSS polymerization and by an inhibitor of strctch-activated cation channels. This cation permeability pathway is likely an important source of intracellular Ca2+ for pathologic activation of KCa3.1 in sickle erythrocytes. Blockade of this pathway represents a novel therapeutic approach for treatment of sickle disease

Sustainable development in the mining industry: Towards the development of tools for evaluating socioeconomic impact in the Canadian context

In spite of its economic outputs, the Canadian mining sector has suffered from several setbacks that have compromised its reputation. This has led many of its stakeholders to adopt a shift towards a new paradigm focused on sustainable development. In this review of the literature, we identify the impact that mining activities have had on various social, economic and environmental issues in Canadian society. We also survey the criteria and indicators included in various models that may be used to evaluate the adequacy of the transition of mines towards sustainable development. Finally, the strengths and weaknesses of eight tools that have been applied to the socioeconomic impact of mines are analysed. A clear vision of prospects for promoting sustainable development in Canadian mining emerges from this survey. Our analysis reveals important factors not given adequate consideration in the models used currently to evaluate and suggests opportunities to improve these evaluation tools through identification of more relevant criteria and indicators. The research undertaken should incite stakeholders to develop social and economic impact evaluation tools that are better adapted to the Canadian context

Multi-criteria evaluation of the socioeconomic impact of mining in Canada from a sustainable development perspective: A theoretical model

The socioeconomic impact of mining in Canada has positive and negative aspects. Effective evaluation of its impact suffers from the inadequacy of the criteria and indicators chosen to measure its sustainability and the limitations of the current means used to minimize the subjectivity of expert judgments. Constraints associated with legislation and standards governing mining activities must also be considered. In this study, a theoretical model is proposed for evaluating the socioeconomic impact of mining in Canada. This model combines the multi-criteria analysis methods known as the analytic hierarchy process and fuzzy integrated judgment. Based on a simulation, the model is able to take into account the subjectivity of expert judgments. In addition to reducing this subjectivity and allowing measurement of sensitivity, the model provided an overview of the progress achieved by a mine during its transition towards sustainable development