Utilization of Guided Bone Regeneration Techniqes in Treatment of a Single Tooth Missing with Implant Supported Crown

Guided bone regeneration is developing very dynamically in dental surgery and in implantology. It relies on building up bone in places where it is lacking, utilizing a variety of grafting materials. Methods of guided bone regeneration utilize biological materials or synthetic specimens. The use of autogenous platelets rich plasma derived in the thromboforetic process (COBE spectra system) allows the employment of growth factors, which blood platelets contain in the formation of new bone tissues. Usage of BioOss together with platelet rich plasmas allows the creation of a resorbable carrier for growth factor (auto-xenogenic graft). The aim of the presentation is the analysis of clinical cases where usage of bone augmentation enabled the insertion of implants. Rebuilding the bone by means of guided bone regeneration facilitated the implant treatment and consequently the accomplishment of fixed prosthetics supported on implants

Follow up Clinical Observations of a Patient with Replantation, Transplantation and Implantation

The paper presents the case of a young female patient treated with T.B.R. implants after unsuccessful replantation. The patient applied for the treatment in the Prosthodontic Department in January 1994, three months after the procedure of retained canine replantation. Before the replantation the patient had been treated with an orthodontic traction device, but the treatment was unsuccessful. The lack of bony restitution and permanent inflammation was the reason for canine extraction and immediate denture application. Bony defect after unsuccessful replantation and canine extraction was the reason for the surgical procedure of augmentation by transplantation from iliac bone 6 months later. Healing after bone augmentation was satisfactory and provided favourable conditions for implant installation. Two cylinder T.B.R. implants were placed in the region of the missing canines in September 1995. After 6 months the healing screws were connected to the implants. After 1 week a small correction of the gingival flap, pulling the mucous membrane on the labial surface, was made on the right side. Healing then proceeded without additional problems. The final prosthetic restorations were made in March 1996.The patient has a regular check-up. The implant mobility is measured with Periotest and depth of gingival pockets with Florida probe

Multipoint genome-wide linkage scan for nonword repetition in a multigenerational family further supports chromosome 13q as a locus for verbal trait disorders

Verbal trait disorders encompass a wide range of conditions and are marked by deficits in five domains that impair a person’s ability to communicate: speech, language, reading, spelling, and writing. Nonword repetition is a robust endophenotype for verbal trait disorders that is sensitive to cognitive processes critical to verbal development, including auditory processing, phonological working memory, and motor planning and programming. In the present study, we present a six-generation extended pedigree with a history of verbal trait disorders. Using genome-wide multipoint variance component linkage analysis of nonword repetition, we identified a region spanning chromosome 13q14–q21 with LOD = 4.45 between 52 and 55 cM, spanning approximately 5.5 Mb on chromosome 13. This region overlaps with SLI3, a locus implicated in reading disability in families with a history of specific language impairment. Our study of a large multigenerational family with verbal trait disorders further implicates the SLI3 region in verbal trait disorders. Future studies will further refine the specific causal genetic factors in this locus on chromosome 13q that contribute to language traits. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00439-016-1717-z) contains supplementary material, which is available to authorized users

Transient anomalous diffusion in periodic systems: ergodicity, symmetry breaking and velocity relaxation

We study far from equilibrium transport of a periodically driven inertial Brownian particle moving in a periodic potential. As detected recently for a SQUID ratchet dynamics (Spiechowicz J. & Luczka J. Phys. Rev. E 91, 062104 (2015)), the mean square deviation of the particle position from its average may involve three distinct intermediate, although extended diffusive regimes: initially as superdiffusion, followed by subdiffusion and finally, normal diffusion in the asymptotic long time limit. Even though these anomalies are transient effects, their lifetime can be many, many orders of magnitude longer than the characteristic time scale of the setup and turns out to be extraordinarily sensitive to the system parameters like temperature or the potential asymmetry. In the paper we reveal mechanisms of diffusion anomalies related to ergodicity of the system, symmetry breaking of the periodic potential and ultraslow relaxation of the particle velocity towards its steady state. Similar sequences of the diffusive behaviours could be detected in various systems including, among others, colloidal particles in random potentials, glass forming liquids and granular gases