Changing the Boston School Choice Mechanism

In July 2005 the Boston School Committee voted to replace the existing Boston school choice mechanism with a deferred acceptance mechanism that simplifies the strategic choices facing parents. This paper presents the empirical case against the previous Boston mechanism, a priority matching mechanism, and the case in favor of the change to a strategy-proof mechanism. Using detailed records on student choices and assignments, we present evidence both of sophisticated strategic behavior among some parents, and of unsophisticated strategic behavior by others. We find evidence that some parents pay close attention to the capacity constraints of different schools, while others appear not to. In particular, we show that many unassigned students could have been assigned to one of their stated choices with a different strategy under the current mechanism. This interaction between sophisticated and unsophisticated players identifies a new rationale for strategy-proof mechanisms based on fairness, and was a critical argument in Boston's decision to change the mechanism. We then discuss the considerations that led to the adoption of a deferred acceptance mechanism as opposed to the (also strategy-proof) top trading cycles mechanism.

DC field induced enhancement and inhibition of spontaneous emission in a cavity

We demonstrate how spontaneous emission in a cavity can be controlled by the application of a dc field. The method is specially suitable for Rydberg atoms. We present a simple argument for the control of emission.Comment: 3-pages, 2figure. accepted in Phys. Rev.

Repulsive Fermions in Optical Lattices: Phase separation versus Coexistence of Antiferromagnetism and d-Superfluidity

We investigate a system of fermions on a two-dimensional optical square lattice in the strongly repulsive coupling regime. In this case, the interactions can be controlled by laser intensity as well as by Feshbach resonance. We compare the energetics of states with resonating valence bond d-wave superfluidity, antiferromagnetic long range order and a homogeneous state with coexistence of superfluidity and antiferromagnetism. We show that the energy density of a hole $e_{hole}(x)$ has a minimum at doping $x=x_c$ that signals phase separation between the antiferromagnetic and d-wave paired superfluid phases. The energy of the phase-separated ground state is however found to be very close to that of a homogeneous state with coexisting antiferromagnetic and superfluid orders. We explore the dependence of the energy on the interaction strength and on the three-site hopping terms and compare with the nearest neighbor hopping {\it t-J} model

Lymphotoxin is an autocrine growth factor for Epstein-Barr virus-infected B cell lines.

Because human lymphotoxin (LT) was originally isolated from a lymphoblastoid cell line, we investigated the role of this molecule in three newly established Epstein-Barr virus (EBV)-infected human B cell lines. These lines were derived from acute lymphoblastic leukemia (Z-6), myelodysplastic syndrome (Z-43), and acute myelogenous leukemia (Z-55) patients who had a prior EBV infection. Each lymphoblastoid cell line had a karyotype that was different from that of the original parent leukemic cells, and all expressed B cell, but not T cell or myeloid surface markers. In all three lines, rearranged immunoglobulin heavy chain joining region (JH) bands were found, and the presence of EBV DNA was confirmed by Southern blotting. Z-6, Z-43, and Z-55 cell lines constitutively produced 192, 48, and 78 U/ml LT, respectively, as assessed by a cytotoxicity assay and antibody neutralization. Levels of tumor necrosis factor (TNF) were undetectable. Scatchard analysis revealed that all the cell lines expressed high-affinity TNF/LT receptors with receptor densities of 4197, 1258, and 1209 sites/cell on Z-6, Z-43, and Z-55, respectively. Furthermore, labeled TNF binding could be reversed by both unlabeled TNF, as well as by LT. Studies with p60 and p80 receptor-specific antibodies revealed that the three lines expressed primarily the p80 form of the TNF receptor. When studied in a clonogenic assay, exogenous LT stimulated proliferation of all three cell lines in a dose-dependent fashion at concentrations ranging from 25 to 500 U/ml. Similar results were obtained with [3H]TdR incorporation. Monoclonal anti-LT neutralizing antibodies at concentrations of 25-500 U/ml inhibited cellular multiplication in a dose-dependent manner. It is interesting that in spite of a common receptor, TNF (1,000 U/ml) had no direct effect on Z-55 cell growth, whereas it partially reversed the stimulatory effect of exogenous LT. In addition, TNF inhibited Z-6 and Z-43 cell proliferation, and its suppressive effect was reversed by exogenous LT. Both p80 and p60 forms of soluble TNF receptors suppressed the lymphoblastoid cell line proliferation and their inhibitory effect was partially reversed by LT. Our data suggest that (a) LT is an autocrine growth factor for EBV-transformed lymphoblastoid B cell lines; and (b) anti-LT antibodies, soluble TNF/LT receptors, and TNF itself can suppress the growth of lymphoblastoid cells, probably by modulating or competing with LT.(ABSTRACT TRUNCATED AT 400 WORDS

pheA (Rv3838c) of Mycobacterium tuberculosis encodes an allosterically regulated monofunctional prephenate dehydratase that requires both catalytic and regulatory domains for optimum activity

Prephenate dehydratase (PDT) is a key regulatory enzyme in l-phenylalanine biosynthesis. In Mycobacterium tuberculosis, expression of pheA, the gene encoding PDT, has been earlier reported to be iron-dependent (1, 2). We report that M. tuberculosis pheA is also regulated at the protein level by aromatic amino acids. All of the three aromatic amino acids (phenylalanine, tyrosine, and tryptophan) are potent allosteric activators of M. tuberculosis PDT. We also provide in vitro evidence that M. tuberculosis PDT does not possess any chorismate mutase activity, which suggests that, unlike many other enteric bacteria (where PDT exists as a fusion protein with chorismate mutase), M. tuberculosis PDT is a monofunctional and a non-fusion protein. Finally, the biochemical and biophysical properties of the catalytic and regulatory domains (ACT domain) of M. tuberculosis PDT were studied to observe that, in the absence of the ACT domain, the enzyme not only loses its regulatory activity but also its catalytic activity. These novel results provide evidence for a monofunctional prephenate dehydratase enzyme from a pathogenic bacterium that exhibits extensive allosteric activation by aromatic amino acids and is absolutely dependent upon the presence of catalytic as well as the regulatory domains for optimum enzyme activity

Transformation strain based method for characterization of convective heat transfer from shape memory alloy wires

While shape memory alloys (SMAs) have many actuation benefits, their frequencies are commonly restricted by slow cooling times caused by limitations in convective heat transfer. To increase the cooling speed and at the same time reduce excess power consumption from overheating, it is critical to understand the heat transfer from SMA wires. This requires accurate surface temperature measurement under a fixed input power, which is difficult to obtain using traditional methods because of the nature of SMAs (thin wires, large strains, heat activation, ambient environment, etc). This paper introduces a non-invasive technique for calculating the convective coefficient for SMAs by employing the temperature-induced transformation strain of SMAs to estimate the surface temperature. This method was experimentally validated for measurement of the convective coefficient in air where infrared cameras can operate, and then used to indirectly measure the convective coefficient across a range of commonly utilized SMA wire diameters and ambient media where traditional methods are limited. Formulated empirical correlations to the collected data provide a mathematical relationship to calculate the convective coefficient in material models which serve as better estimates of convection, and may be used for optimization of SMA actuators for increased frequency performance while ensuring that power draw is minimized.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/85423/1/sms10_3_035005.pd

High accuracy short-term PWV operational forecast at the VLT and perspectives for sky background forecast

In this paper we present the first results ever obtained by applying the autoregressive (AR) technique to the precipitable water vapour (PWV). The study is performed at the Very Large Telescope. The AR technique has been recently proposed to provide forecasts of atmospheric and astroclimatic parameters at short time scales (up to a few hours) by achieving much better performances with respect to the 'standard forecasts' provided early afternoon for the coming night. The AR method uses the real-time measurements of the parameter of interest to improve the forecasts performed with atmospherical models. We used here measurements provided by LHATPRO, a radiometer measuring continuously the PWV at the VLT. When comparing the AR forecast at 1h to the standard forecast, we observe a gain factor of $\sim$ 8 (i.e. $\sim$ 800 per cent) in terms of forecast accuracy. In the PWV $\leq$ 1 mm range, which is extremely critical for infrared astronomical applications, the RMSE of the predictions is of the order of just a few hundredth of millimetres (0.04 mm). We proved therefore that the AR technique provides an important benefit to VLT science operations for all the instruments sensitive to the PWV. Besides, we show how such an ability in predicting the PWV can be useful also to predict the sky background in the infrared range (extremely appealing for METIS). We quantify such an ability by applying this method to the NEAR project (New Earth in the Alpha Cen region) supported by ESO and Breakthrough Initiatives