Discovery Potential for New Phenomena

We examine the ability of future facilities to discover and interpret non-supersymmetric new phenomena. We first explore explicit manifestations of new physics, including extended gauge sectors, leptoquarks, exotic fermions, and technicolor models. We then take a more general approach where new physics only reveals itself through the existence of effective interactions at lower energy scales. [Summary Report of the New Phenomena Working Group. To appear in the Proceedings of the 1996 DPF/DPB Summer Study on New Directions for High Energy Physics - Snowmass96, Snowmass, CO, 25 June - 12 July 1996.]Comment: 18 pages, LaTex2

Physical degrees of freedom in stabilized brane world models

We consider brane world models with interbrane separation stabilized by the Goldberger-Wise scalar field. For arbitrary background, or vacuum configurations of the gravitational and scalar fields in such models, we construct the second variation Lagrangian, study its gauge invariance, find the corresponding equations of motion and decouple them in a suitable gauge. We also derive an effective four-dimensional Lagrangian for such models, which describes the massless graviton, a tower of massive gravitons and a tower of massive scalars. It is shown that for a special choice of the background solution the masses of the graviton excitations may be of the order of a few TeV, the radion mass of the order of 100 GeV, the inverse size of the extra dimension being tens of GeV. In this case the coupling of the radion to matter on the negative tension brane is approximately the same as in the unstabilized model with the same values of the fundamental five-dimensional energy scale and the interbrane distance.Comment: 17 pages, LaTeX, corrected typos, amended the normalization constants of the scalar modes and their coupling constants to matte

From an automated flight-test management system to a flight-test engineer's workstation

The capabilities and evolution is described of a flight engineer's workstation (called TEST-PLAN) from an automated flight test management system. The concept and capabilities of the automated flight test management systems are explored and discussed to illustrate the value of advanced system prototyping and evolutionary software development

Indirect Collider Signals for Extra Dimensions

A recent suggestion that quantum gravity may become strong near the weak scale has several testable consequences. In addition to probing for the new large (submillimeter) extra dimensions associated with these theories via gravitational experiments, one could search for the Kaluza Klein towers of massive gravitons which are predicted in these models and which can interact with the fields of the Standard Model. Here we examine the indirect effects of these massive gravitons being exchanged in fermion pair production in \epem annihilation and Drell-Yan production at hadron colliders. In the latter case, we examine a novel feature of this theory, which is the contribution of gluon gluon initiated processes to lepton pair production. We find that these processes provide strong bounds, up to several TeV, on the string scale which are essentially independent of the number of extra dimensions. In addition, we analyze the angular distributions for fermion pair production with spin-2 graviton exchanges and demonstrate that they provide a smoking gun signal for low-scale quantum gravity which cannot be mimicked by other new physics scenarios.Comment: Corrected typos, added table and reference

Signals for Vector Leptoquarks in Hadronic Collisions

We analyze systematically the signatures of vector leptoquarks in hadronic collisions. We examine their single and pair productions, as well as their effects on the production of lepton pairs. Our results indicate that a machine like the CERN Large Hadron Collider (LHC) will be able to unravel the existence of vector leptoquarks with masses up to the range of $2$--$3$ TeV.Comment: 15 pages and 5 figures (available upon request or through anonymous ftp), revtex3, IFUSP-P 108

pMSSM Benchmark Models for Snowmass 2013

We present several benchmark points in the phenomenological Minimal Supersymmetric Standard Model (pMSSM). We select these models as experimentally well-motivated examples of the MSSM which predict the observed Higgs mass and dark matter relic density while evading the current LHC searches. We also use benchmarks to generate spokes in parameter space by scaling the mass parameters in a manner which keeps the Higgs mass and relic density approximately constant.Comment: 10 pages, 6 figure

Discovery Potential for New Phenomena

We examine the ability of future facilities to discover and interpret non-supersymmetric new phenomena. We first explore explicit manifestations of new physics, including extended gauge sectors, leptoquarks, exotic fermions, and technicolor models. We then take a more general approach where new physics only reveals itself through the existence of effective interactions at lower energy scales. [Summary Report of the New Phenomena Working Group. To appear in the Proceedings of the 1996 DPF/DPB Summer Study on New Directions for High Energy Physics - Snowmass96, Snowmass, CO, 25 June - 12 July 1996.

Celecoxib concentration predicts decrease in prostaglandin E\u3csub\u3e2\u3c/sub\u3e concentrations in nipple aspirate fluid from high risk women

BACKGROUND: Epidemiologic studies suggest that long term low dose celecoxib use significantly lowers breast cancer risk. We previously demonstrated that 400 mg celecoxib taken twice daily for 2 weeks lowered circulating plasma and breast nipple aspirate fluid (NAF) prostaglandin (PG)E2 concentrations in post- but not premenopausal high risk women. We hypothesized that circulating concentrations of celecoxib influenced PGE2 response, and that plasma levels of the drug are influenced by menopausal status. To address these hypotheses, the aims of the study were to determine: 1) if circulating plasma concentrations of celecoxib correlated with the change in plasma or NAF PGE2 concentrations from baseline to end of treatment, and 2) whether menopausal status influenced circulating levels of celecoxib. METHODS: Matched NAF and plasma were collected from 46 high risk women who were administered celecoxib twice daily for two weeks, 20 subjects receiving 200 mg and 26 subjects 400 mg of the agent. NAF and plasma samples were collected before and 2 weeks after taking celecoxib. RESULTS: In women taking 400 mg bid celecoxib, plasma concentrations of the agent correlated inversely with the change in NAF PGE2 levels from pre- to posttreatment. Nonsignificant trends toward higher celecoxib levels were observed in post- compared to premenopausal women. There was a significant decrease in NAF but not plasma PGE2 concentrations in postmenopausal women who took 400 mg celecoxib (p = 0.03). CONCLUSION: In high risk women taking 400 mg celecoxib twice daily, plasma concentrations of celecoxib correlated with downregulation of PGE2 production by breast tissue. Strategies synergistic with celecoxib to downregulate PGE2 are of interest, in order to minimize the celecoxib dose required to have an effect

Brane Localized Curvature for Warped Gravitons

We study the effects of including brane localized curvature terms in the Randall-Sundrum (RS) model of the hierarchy. This leads to the existence of brane localized kinetic terms for the graviton. Such terms can be induced by brane and bulk quantum effects as well as Higgs-curvature mixing on the brane. We derive the modified spectrum of Kaluza-Klein (KK) gravitons and their couplings to 4-dimensional fields in the presence of these terms. We find that the masses and couplings of the KK gravitons have considerable dependence on the size of the brane localized terms; the weak-scale phenomenology of the model is consequently modified . In particular, the weak-scale spin-2 graviton resonances which generically appear in the RS model may be significantly lighter than previously assumed. However, they may avoid detection as their widths may be too narrow to be observable at colliders. In the contact interaction limit, for a certain range of parameters, the experimental reach for the scale of the theory is independent of the size of the boundary terms.Comment: 20 pages, 11 figures, LaTex, minor revision