Systematic bibliometric review of artificial intelligence technology in organizational management, development, change and culture

Even now, in the times of advanced digitization, the planning and implementation of many organizational measures remain human-driven. Corresponding to a global trend of application of artificial intelligence in all areas of life, it has received more attention in the last few years and garnered emerging clusters of research in usage of this technology for organizational issues. Some companies already offer tools that support different management tasks in the area of organizational development, but they are not holistic. According to the google trend analysis of the search for artificial intelligence, the inquiry to this topic continues increasing. The purpose of the described investigation was to identify the academic trends in research interaction between such scientific fields, as Artificial Intelligence, Organizational Management, Organizational Development, Organizational Change, and Organizational Culture using bibliometric and network publication analysis. In order to achieve this purpose, we systematically analysed 191 publications between 1983 and 2020 as well as cited and citing publications. The findings of this study provide important conclusions of the current research state. The insightful results are presented in the form of critical review and frame the body of knowledge

Activity of a K-ATP(+) channel in Arum spadix mitochondria during thermogenesis

This report demonstrates that mitochondria isolated from thermogenic Arum spadices possess an ATP-sensitive potassium channel \u2013 responsible for electrical potential (DC) collapse and mitochondrial swelling \u2013 whose characteristics are similar to those previously described in pea and wheat mitochondria. In order to study the relationship between this K+ATP channel and the uncoupled respiration, linked to thermogenesis, K+ transport activities were compared with those of mitochondria that were isolated from pea stems, soybean suspension cell cultures and Arum tubers. The channel from Arum spadices is highly active and its major features are (i) potassium flux is performed primarily in an inward-rectifying manner; (ii) the influx of K+ is associated with a matrix volume increase in both energized and non-energized mitochondria; and (iii) its activity depends on the redox state of electron transport chain (ETC) and oxygen availability. In particular, this paper shows that the K+ ATP channel is inwardly activated in parallel with the alternative oxidase (AO). The activation is linked to an ETC-oxidized state and to high oxygen consumption. The putative role of this K+ATP channel is discussed in relation to flowering of thermogenic Arum spadices

Mitochondrial bioenergetics linked to the manifestation of programmed cell death during somatic embryogenesis of Abies alba

The present work reports changes in bioenergetic parameters and mitochondrial activities during the manifestation of two events of programmed cell death (PCD), linked toAbies albasomatic embryogenesis. PCD, evidenced by in situ nuclear DNA fragmentation (TUNEL assay), DNA laddering and cytochrome c release, was decreased in maturing embryogenic tissue with respect to the proliferation stage. In addition, the major cellular energetic metabolites (ATP, NAD(P)H and glucose-6-phosphate) were highered during maturation. The main mitochondrial activities changed during two developmental stages. Mitochondria, isolated from maturing, with respect to proliferating cell masses, showed an increased activity of the alternative oxidase, external NADH dehydrogenase and fatty-acid mediated uncoupling. Conversely, a significant decrease of the mitochondrial KATP ? channel activity was observed. These results suggest a correlation between mitochondrial activities and the manifestation of PCD during the development of somatic embryos. In particular, it is suggested that the KATP ? channel activity could induce an entry of K+ into the matrix, followed by swelling and a release of cytochrome cduring proliferation, whereas the alternative pathways, acting as anti-apoptotic factors, may partially counteract PCD events occurring during maturation of somatic embryos

Isolation of mitochondria from embryogenic cultures of Picea abies (L.) Karst. and Abies cephalonica Loud.: Characterization of a KATP + channel

A valuable method to isolate and purify mitochondria from embryonal masses of two coniferous species (Picea abies [L.] Karst. and Abies cephalonica Loud.) is described. Crude mitochondria from both species were shown to be intact, oxygen consuming (with malate plus glutammate, succinate and NADH as substrates) and well coupled (respiratory control ratio ca. 4). The oxidation of the substrates was only partially KCN-insensitive (alternative oxidase) in some cases. However, these fractions were contaminated by membranes (e.g. plasmalemma, tonoplast, Golgi and endoplasmic reticulum). After purification by a discontinuous Percoll gradient (18, 23, 40%, v/v), three mitochondrial populations were separated. The 0/18 interface fraction was composed mainly of broken and uncoupled mitochondria, while the other two (18/23 and 23/40 interface fractions) contained intact and coupled mitochondria, but only 23/40 interface fraction revealed to be better purified starting from both coniferous embryonal masses. In the latter purified fraction, the presence of a cyclosporin A-sensitive KATP + channel was demonstrated. These findings were discussed in the light of the potential use of these mitochondrial fractions in bioenergetic studies, or in the involvement of these organelles to stress response in conifers. \ua9 2007 Springer-Verlag

Plant mitochondrial pathway leading to programmed cell death

Programmed cell death (PCD) is a finely tuned process of multicellular organisms. In higher plants, PCD regulates many developmental processes and the response of host plants to incompatible pathogens (hypersensitive response). Four types of PCD have been described in plants, mainly associated to vacuole rupture, that is followed by the appearance of the typical PCD hallmarks (i.e. nuclear DNA fragmentation and cell shrinkage). However, in some cases vacuole collapse is preceded by an early alteration of other subcellular organelles, such as mitochondria. In particular, the central role played by mitochondria in PCD has been largely recognised in animal cells. This review deals with the involvement of mitochondria in the manifestation of plant PCD, in comparison to that described in animal PCD. The main hallmark, connecting animal and plant PCD via mitochondria, is represented by the release of cytochrome c and possibly other chemicals such as nucleases, which may be accomplished by different mechanisms, involving both swelling and non-swelling of the organelles

Effect of humic acids on phosphate level and energetic metabolism of tobacco BY-2 suspension cell cultures

To investigate the role of natural humic substances on plant cell phosphate level and metabolism, tobacco BY-2 suspension cell cultures were grown in the presence of humic samples of different chemical composition: soil humic acid and its three size-fractions (I-III) separated by High Pressure Size Exclusion Chromatography. The humic samples were characterized by CPMAS-NMR spectroscopy and on-line pyrolysis-gas chromatography-mass spectrometry. Suspension cell cultures, after 7 days of incubation, were facing Pi starvation. The fraction III, the most hydrophilic and smallest in molecular size among humic samples, induced a partial relief from Pi starvation, increasing total cell phosphate amount, ATP and glucose-6-phosphate levels, as well as the activity of secreted acid phosphatases. Furthermore, fraction III induced a decrease of KCN-insensitive respiration, evaluated in both suspension cells and isolated mitochondria. The low amount of acidic groups in fraction III excluded that its observed effect in relieving cells from Pi deficiency may be attributed to a partial replacement of the chelating ability of secreted acids (mainly citric and malic acids) in releasing Pi from metal-phosphate complexes. The molecular characteristics of fraction III are conducive to a flexible conformational structure due to hydrophilic domains, which are still contoured by hydrophobic moieties such as alkyl and aromatic compounds. Such flexible molecular associations may induce an efficient release of Pi from organic sources (e.g. nucleic acids), released in the media by damaged or dead cells, exerting a sort of positive effect on either the production or activity of extracellular Pi hydrolytic enzymes. This work shows that only by combining advanced molecular characterization of natural humic molecules with their effect on plant cells, it is possible to formulate sound hypotheses for structure-activity relationships