Shop Notes

Contains a report on a research project

Letters of concern, condolences, and sympathy from friends and relatives upon the illness and subsequent death of Mr. Fleming on December 20, 1908.

Correspondents include J.E. Ingraham. Letters with accompanying envelopes have written answered on them, 1908-12-16 - 1909-02-1

Levels of Ca\u3csub\u3ev\u3c/sub\u3e1.2 L-Type Ca\u3csup\u3e2+\u3c/sup\u3e Channels Peak in the First Two Weeks in Rat Hippocampus Whereas Ca\u3csub\u3ev\u3c/sub\u3e1.3 Channels Steadily Increase through Development

Influx of calcium through voltage-dependent channels regulates processes throughout the nervous system. Specifically, influx through L-type channels plays a variety of roles in early neuronal development and is commonly modulated by G-protein-coupled receptors such as GABAB receptors. Of the four isoforms of L-type channels, only Cav1.2 and Cav1.3 are predominately expressed in the nervous system. Both isoforms are inhibited by the same pharmacological agents, so it has been difficult to determine the role of specific isoforms in physiological processes. In the present study, Western blot analysis and confocal microscopy were utilized to study developmental expression levels and patterns of Cav1.2 and Cav1.3 in the CA1 region of rat hippocampus. Steady-state expression of Cav1.2 predominated during the early neonatal period decreasing by day 12. Steady-state expression of Cav1.3 was low at birth and gradually rose to adult levels by postnatal day 15. In immunohistochemical studies, antibodies against Cav1.2 and Cav1.3 demonstrated the highest intensity of labeling in the proximal dendrites at all ages studied (P1–72). Immunohistochemical studies on one-week-old hippocampi demonstrated significantly more colocalization of GABAB receptors with Cav1.2 than with Cav1.3, suggesting that modulation of L-type calcium current in early development is mediated through Cav1.2 channels

Gaseous Electronics

Contains reports on one research project.Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 36-039-AMC-03200(E

“Being believed, being seen, not being questioned”: Bisexual women’s experiences of validity while passing as heterosexual

Abstract The current study explored bisexual cisgender women’s experiences regarding passing as heterosexual, which Dyar et al. (2014) defined as the perception that one’s bisexual identity can be concealable and that bisexual individuals can choose to appear heterosexual with different-gender partners to avoid heterosexism. Utilizing intersectionality (Crenshaw, 1989/1993) and Brown’s (2002) bisexual identity development model as the theoretical framework, the present study related passing as heterosexual to bisexual individuals’ identity validity while exploring factors that facilitate or hinder this process. This qualitative study explored the experiences of 12 bisexual cisgender adult women through semi-structured interviews in the constructivist-interpretivist paradigm (Ponterotto, 2005). Interviews were conducted using Skype or phone and analyzed using Interpretive Phenomenological Analysis (IPA) methodology (Smith & Osborn, 2008). Emerging themes were discussed with support from participants’ quotes regarding their experiences. Themes included factors related to passing as heterosexual as well as the impact of intersectionality on decision-making for coming out versus continuing to pass. Themes also captured validity-hindering factors (assumptions of heterosexuality, experiences of invalidation, and negative relationships with the LGBTQIA+ community) and validity-facilitating factors (specific experiences of external and internal validation, recommendations for others). Clinical implications informed by an intersectional focus and limitations of the study were also discussed

Bostonia. Volume 3

Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs

The proton and electron radiation belts at geosynchronous orbit: Statistics and behavior during high‐speed stream‐driven storms

The outer proton radiation belt (OPRB) and outer electron radiation belt (OERB) at geosynchronous orbit are investigated using a reanalysis of the LANL CPA (Charged Particle Analyzer) 8‐satellite 2‐solar cycle energetic particle data set from 1976 to 1995. Statistics of the OPRB and the OERB are calculated, including local time and solar cycle trends. The number density of the OPRB is about 10 times higher than the OERB, but the 1 MeV proton flux is about 1000 times less than the 1 MeV electron flux because the proton energy spectrum is softer than the electron spectrum. Using a collection of 94 high‐speed stream‐driven storms in 1976–1995, the storm time evolutions of the OPRB and OERB are studied via superposed epoch analysis. The evolution of the OERB shows the familiar sequence (1) prestorm decay of density and flux, (2) early‐storm dropout of density and flux, (3) sudden recovery of density, and (4) steady storm time heating to high fluxes. The evolution of the OPRB shows a sudden enhancement of density and flux early in the storm. The absence of a proton dropout when there is an electron dropout is noted. The sudden recovery of the density of the OERB and the sudden density enhancement of the OPRB are both associated with the occurrence of a substorm during the early stage of the storm when the superdense plasma sheet produces a “strong stretching phase” of the storm. These storm time substorms are seen to inject electrons to 1 MeV and protons to beyond 1 MeV into geosynchronous orbit, directly producing a suddenly enhanced radiation belt population.Key PointsDuring high‐speed stream‐driven storms, the electron and proton radiation belts are directly enhanced by a single substormThe enhancing substorm occurs during the “strong stretching” phase of the storm caused by the superdense plasma sheetProton and electron injection to 1 MeV is seen for these strong stretching phase substormsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/133567/1/jgra52702.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/133567/2/jgra52702_am.pd