12 research outputs found
Characteristics of left ventricular contraction patterns and acute changes with multisite pacing in patients with heart failure as assessed by echocardiographic semiautomatic contour detection
No full textStructural and functional studies of Bud23-Trm112 reveal 18S rRNA N7-G1575 methylation occurs on late 40S precursor ribosomes
No full textInternational audienceRibosomes are essential cellular nanomachines responsible for all protein synthesis in vivo. Efficient and faithful ribosome biogenesis requires a plethora of assembly factors whose precise role and timing of action remains to be established. Here we determined the crystal structure of Bud23–Trm112, which is required for efficient pre-rRNA processing steps leading to 18S rRNA synthesis and methylation of 18S rRNA at position G1575. For the first time, to our knowledge, we identified where on Bud23–Trm112 the contacts with precursor ribosomes occur. We further report that the essential helicase Dhr1 interacts directly with Bud23–Trm112, proposing a concerted action of these proteins in ribosome assembly. Finally, we reveal that the methyltransferase activity of Bud23–Trm112 and its requirement for pre-rRNA processing are disconnected in time
Effect of left ventricular stimulation site on the contractile function of heart failure patients with biventricular resynchronization therapy
No full textPacing therapies for congestive heart failure study group echocardiographic : quantification of left ventricular asynchrony predicts acute benefit of cardiac resynchronization therapy in patients with heart failure and conduction delay
No full textCharacteristics of left ventricular contraction patterns and acute changes with multisite pacing in patients with heart failure as assessed by echocardiographic semiautomatic contour detection
No full textEffect of left ventricular stimulation site on the contractile function of heart failure patients with biventricular resynchronization therapy
No full textSurveillance épidémiologique de la Poliomyélite. Virus de la polio & enterovirus non-polio - 2022
No full textAucun cas de poliomyĂ©lite n’a Ă©tĂ© signalĂ© en Belgique depuis 1999.
La Belgique est actuellement classĂ©e dans la catĂ©gorie des pays Ă risque intermĂ©diaire de transmission de la poliomyĂ©lite selon l’OMS.
La couverture vaccinale reste élevée (97,6 %, 3 doses), mais des populations vulnérables existent et sont toujours à risque.
Trois cas de paralysie flasque aiguë ont été signalés en 2022. Pour avoir une surveillance suffisamment sensible, 19 cas auraient dû être déclarés.
Les systèmes de surveillance actuels nĂ©cessitent un engagement plus important de la part des professionnels de la santĂ© afin d’amĂ©liorer leur couverture.
La mise en œuvre de la surveillance des eaux usées peut compléter les systèmes de surveillance actuels.</p
Epidemiologische surveillance van poliomyelitis. Poliovirus & niet-polio enterovirusssen - 2022
No full textSinds 1999 zijn er in België geen gevallen van poliomyelitis gemeld.
België is momenteel door de WGO geclassificeerd als een land met een gemiddeld risico op overdracht van polio.
De vaccinatiegraad blijft hoog (97,6%, 3 doses), maar kwetsbare bevolkingsgroepen lopen nog steeds risico.
In 2022 werden drie gevallen van acute slappe verlamming gemeld. Om voldoende bewakingsgevoeligheid te hebben, hadden er 19 gevallen gemeld moeten worden.
De huidige surveillancesystemen vereisen een grotere betrokkenheid van professionals in de gezondheidszorg om de dekking ervan te verbeteren.
De implementatie van afvalwatermonitoring kan bestaande monitoringsystemen aanvullen.</p
