15 research outputs found
Low Seroprevalence of West Nile Virus in Blood Donors from Catalonia, Spain
West Nile virus (WNV) is an emerging arbovirus first recognized
in Europe in the 1950s. Since then, outbreaks have been reported
in several European countries. In 2010, the first WNV outbreak
was recorded in Spain, affecting the southern part of the
country. We conducted a seroprevalence study in the Catalonia
region (northeastern Spain), an area considered at high risk of
arbovirus transmission. A total of 800 serum samples from blood
donors were collected and screened for antibodies against WNV by
enzyme-linked immunosorbent assay (ELISA) and confirmed by a
microneutralization assay. More than 50 samples tested positive
by ELISA, but only one sample contained neutralizing antibodies
against WNV and was obtained from a donor native of Pakistan.
The low seroprevalence detected may serve as reference baseline
data for monitoring WNV activity in our region in future years
Low Seroprevalence of West Nile Virus in Blood Donors from Catalonia, Spain
West Nile virus (WNV) is an emerging arbovirus first recognized
in Europe in the 1950s. Since then, outbreaks have been reported
in several European countries. In 2010, the first WNV outbreak
was recorded in Spain, affecting the southern part of the
country. We conducted a seroprevalence study in the Catalonia
region (northeastern Spain), an area considered at high risk of
arbovirus transmission. A total of 800 serum samples from blood
donors were collected and screened for antibodies against WNV by
enzyme-linked immunosorbent assay (ELISA) and confirmed by a
microneutralization assay. More than 50 samples tested positive
by ELISA, but only one sample contained neutralizing antibodies
against WNV and was obtained from a donor native of Pakistan.
The low seroprevalence detected may serve as reference baseline
data for monitoring WNV activity in our region in future years