Evidence application for property management

The passportization is the process of gathering information about a managed property, which is connected to the processes of planning processes and activities leading to the efficient management of the trust property. The aim of this paper is to highlight the importance of passportization and the resulting evidence in asset management. Applying different kinds of evidence in the management of property management is an essential tool for the entire process of planning, implementing and monitoring such as billing for services performed. Content requirements of each type of evidence, submits to the performance needs of property management. Deepening awareness of the passportization provides practical application of this approach not only upon evidence of the property, but also for the planning of asset management at all levels of management (strategic, tactical, and operational

Structural and biochemical characterization of the novel serpin Iripin 5 from Ixodes Ricinus

Iripin-5 is the main Ixodes ricinus salivary serpin, which acts as a modulator of host defence mechanisms by impairing neutrophil migration, suppressing nitric oxide production by macrophages and altering complement functions. Iripin-5 influences host immunity and shows high expression in the salivary glands. Here, the crystal structure of Iripin-5 in the most thermodynamically stable state of serpins is described. In the reactive-centre loop, the main substrate-recognition site of Iripin-5 is likely to be represented by Arg342, which implies the targeting of trypsin-like proteases. Furthermore, a computational structural analysis of selected Iripin-5–protease complexes together with interface analysis revealed the most probable residues of Iripin-5 involved in complex formation