23 research outputs found
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
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University Scholars Day
Keynote address for the 2007 University Scholars Day delivered by Dr. Edward Dzialowski, This keynote speaker discusses the development of respiratory and cardiovascular systems using avian models
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University Scholars Day
Presentation for the 2009 University Scholars Day at the University of North Texas discussing research on reactive oxygen species role in the closure of the Ductus Arteriosus (DA)
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University Scholars Day
Presentation for the 2007 University Scholars Day at the University of North Texas. This presentation discusses research on characterizing the changes in tissue morphology occurring in the emu ductus arteriosus during hatching and what role apoptosis plays during the process of the ductus closure
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University Scholars Day
Poster for the 2010 University Scholars Day at the University of North Texas discussing a study of the aging process
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University Scholars Day
Presentation for the 2007 University Scholars Day at the University of North Texas discussing research on respiratory and cardiovascular responses in internally pipped chicken embryos
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University Scholars Day
Poster presentation for the 2010 University Scholars Day at the University of North Texas discussing research on measuring the activity of the SERCA using Thapsigargin as a Ca+ ion pump inhibitor
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University Scholars Day
Presentation for the 2011 University Scholars Day at the University of North Texas discussing research on hypoxic effects on contraction of the ductus arteriosus (DA) in the chicken embryo