An Investigation into Ontology-Based Enhancement of Search Technologies for E-Government: Literature Review

Services provided by E-government are no longer considered as a new topic, there is a continuous evolution of the level of services provided by the E-government that matches the development of the techniques and technologies used. The success or failure of E-government builds mainly on providing different services to citizens in a suitable and effective manner. This research study aims at providing an empirical and evaluation study of the effects and the opportunities of implementing various techniques in the development of E-government. The research focuses on the impact of using ontology technique on the success or failure of the services provided by E-government. The services provided to citizens are expanded from information extraction to vote, tax, and other services. It becomes necessary to provide a detail description of the most appropriate technologies in order to reach to a successful E-government which provides effective services

Automatic mapping of XML documents into relational database

Extensible Markup Language (XML) nowadays is one of the most important standard media used for exchanging and representing data through the Internet. Storing, updating and retrieving the huge amount of web services data such as XML is an attractive area of research for researchers and database vendors. In this thesis, we propose and develop a new mapping model, called MAXDOR, for storing, rebuilding, updating and querying XML documents using a relational database without making use of any XML schemas in the mapping process. The model addressed the problem of solving the structural hole between ordered hierarchical XML and unordered tabular relational database to enable us to use relational database systems for storing, updating and querying XML data. A multiple link list is used to maintain XML document structure, manage the process of updating document contents and retrieve document contents efficiently. Experiments are done to evaluate MAXDOR model. MAXDOR will be compared with other well-known models available in the literature(Tatarinov et al., 2002) and (Torsten et al., 2004) using total expected value of rebuilding XML document execution time and insertion of token execution time.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Pharmacovigilance and Adverse Drug Reactions Reporting Process in West-Bank, Palestine

Active national pharmacovigilance programmes are needed to monitor adverse drug reaction (ADR) data in local populations. The objective of this study was to describe the knowledge, experiences, attitudes and perceived barriers to reporting of suspected ADRs by community and hospital pharmacists in West Bank, Palestine. Between December 2014 and March 2015 we conducted a survey about the knowledge and attitude of pharmacists (n = 270) using a face-to-face questionnaire. The questionnaire consisted of questions about the sociodemographic characteristics of the pharmacists, their knowledge of pharmacovigilance and their attitudes towards ADR reporting. Main outcomes measured: The majority of the pharmacists (62.6%) worked in the community pharmacies and more females responded to the questionnaire than males (59% vs 41%). only 11.9% could conceptually or actually define ‘pharmacovigilance’ correctly while one quarter of the respondent pharmacist (24.9%) could define ADR correctly. The hospital clinical pharmacists defined ‘pharmacovigilance’ correctly with higher significance (P<0.001) when compared with community pharmacists. Only 12.2% had ever reported an ADR. The majority of these reports (85%) done by the hospital pharmacists (p<0.0001). The main reasons that discourage the pharmacists from reporting ADRs were ‘‘no enough information available from the patient (76.7%)’’, and ‘‘they did not know how to report (66.7%)’’. The majority of the respondents (92.0%) felt that reporting ADR was their duty and (82%) participants were interested in participating in the National Pharmacovigilance Programme in Palestine. The results show that Palestinian pharmacists have poor knowledge about pharmacovigilance. There is an urgent need for educational programs to train them about pharmacovigilance and ADR reporting scheme

Diclofenac Codrugs and Prodrugs-Three Decades of Design

Prodrugs or predrugs are inactive molecules which become active after in vivo conversion to release the active parent drug. The prodrug’s cleavage can be catalyzed by metabolic enzymes or can occur by chemical means without the involvement of enzymes. Prodrugs are designed to improve undesirable physicochemical and pharmacokinetic properties of their parent drugs. Non-steroidal anti-inflammatory (NSAIDs) drugs are among the most commonly used drugs for treatment of pain, inflammation and fever. Despite their frequent use, these agents suffer from gastrointestinal side effects that limit their use for those patients with gastrointestinal conditions. This mini review discusses the design, synthesis and pharmacological effects of prodrugs and codrugs of the non-steroidal anti-inflammatory (NSAIDs) Diclofenac sodium or potassium. It argues that the prodrug approach has the potential to eliminate Diclofenac associated gastrointestinal complications, increases its bioavailability and masks its bitter taste

The prevalence of smartphone addiction and its related risk factors among Palestinian high school students: a cross-sectional study

BackgroundSmartphone addiction is a significant social and health problem. There is limited research on smartphone addiction in Palestine. The current study aimed to assess the prevalence of smartphone addiction and its association with sociodemographic variables, depression, anxiety, and social support among 12th grade students.MethodsThe study utilized a cross-sectional research design. A self-reported questionnaire, including the Smartphone Addiction Scale (SPAS), the OSLO Social Support Scale, and the Hospital Anxiety and Depression Scale (HADS), was used to gather data.ResultsA total of 1,083 participants were recruited, of whom 27.3% had depression, 50.5% had anxiety, 57.3% experienced smartphone addiction, and 17.6% had strong social support. The study found that students with weak or moderate teacher relationships (AOR: 2.854, p &lt; 0.001), disrupted sleep with smartphones (AOR: 2.143, p &lt; 0.001), negative impact of smartphone usage on studies (AOR: 3.016, p &lt; 0.001), and poor or weak social support (AOR: 3.051, p &lt; 0.001) were at risk of smartphone addiction. Participants who reported no impact on their sleep time (AOR: 0.478, p-value = 0.001), used smartphones for less than 2 hours daily (AOR: 0.347, p &lt; 0.001), and used smartphones for 2 to 3 hours daily (AOR: 0.684, p = 0.037) were less likely to develop smartphone addiction.ConclusionSmartphone addiction was prevalent in high school students in this study. Weak teacher relationships, sleep disturbances, negative academic effects, and insufficient social support may lead to smartphone addiction. Programs that educate students, parents, and educators on smartphone addiction can prevent it and help detect and manage smartphone use problems

Pharmacists’ Knowledge, Attitudes and Practices Towards Herbal Remedies In West Bank, Palestine

Background: There is an increasing trend towards consumption of complementary and alternative herbal products in many parts of the world. Objectives: The purpose of this study was to investigate the knowled - ge and attitudes among pharmacists in West Bank, Palestine towards the use of herbs. Methods: Self-administered questionnaire was designed as the study instrument and distributed among 350 qualified pharmacists working in government and private pharmacies in West Bank, Palestine. Results: The response rate was 82.9% (290/350). The mean age of the pharmacists was 32.9 (SD=6.5) years. The majority of the phar - macist 238 (82.1%) worked in the community pharmacies and their experience in practice ranged from 1 to 26 years. Product package instructions and product representative were the most consulted by the pharmacists (128; 44.2% and 73; 25.2% respectively). General health tonic preparations were the most widely dispensed drugs (142; 48.9%), followed by cough preparations (55; 19.0%) and slimming agents (64; 22.1%). The Majority of pharmacists (195; 67.2%) belie - ved herbal remedies were effective; however, about fifty percent of the pharmacists had concern about their safety. The knowledge of respondents about the indications of herbal medicine was good, but their awareness of interactions, contraindications and adverse effects was inadequate. The majority of Pharmacists (255; 87.9%) believed that herbal product should undergo increased regulation and (215; 74.9%) believed that information available about herbal and natural product isn't adequate

Depression, anxiety and coping strategies among Palestinian university students during political violence: a cross sectional study

Background: There are numerous wars and ongoing political violence in Palestine and little is known about how they have affected Palestinian undergraduate students’ mental health and coping strategies. This study aimed to assess the prevalence of depression, and anxiety symptoms and coping mechanisms among Palestinian university students during the times of current political violence in Palestine after October 7, 2023. Methods: A cross-sectional descriptive study design was utilized for a sample of students from 3 universities in Palestine (Al Quds University, Hebron University, and An-Najah University) and 1815 participants responded. Data were collected using self-reported questionnaires, including Hospital Anxiety and Depression Scale (HADS) and Brief COPE scale. Person correlation test, chi-square test, and bivariate analysis were performed to examine the associations between research variables. Results: The estimated prevalence of depression was 65.9, and 60.9% for anxiety. The logistic regression showed that students from the Arts Faculty, females, and those with working parents were significantly more likely to experience depression and anxiety symptoms. Also, active coping, emotional support, and humor reduced the likelihood of experiencing depression symptoms, while active coping, positive reframing, humor, and acceptance decreased the likelihood of developing anxiety symptoms. Further, the study found that using religion, self-blame, denial, and behavioral disengagement increased the likelihood of depression symptoms while planning, venting, religion, self-blame, denial, and behavioral disengagement increased the likelihood of anxiety symptoms. Conclusion: The study found that political violence often leads to symptoms of depression and anxiety among undergraduates. Furthermore, the use of maladaptive coping mechanisms increases the likelihood that these symptoms will occur. Providing immediate assistance to university students affected by political violence and conflicts is crucial for their emotional and mental recovery and coping with difficulties