5 research outputs found
The Causality Relationship between Hnx Index and Stock Trading Volume in Hanoi Stock Exchange
This paper examines the casual relations between the market return and trading volume for the Ha Noi Stock Exchange during the period from May 3th , 2013 to March 2rd, 2016. This paper uses Granger test and the results showed that the change of the volume of transactions that affect the change of HNX-Index. On the basis of this conclusion, we shall determine the degree of influence of the change in trading volume with HNX-Index by means of regression analysis
Myricetin Prevents Fibrillogenesis of Hen Egg White Lysozyme
Myricetin is a natural flavonol found in many grapes, berries, fruits, vegetables, and herbs as well as other plants.
Recent studies have identified potential antiamyloidogenic activity for this compound. In this study, the kinetics of amyloid fibril
formation by hen egg white lysozyme (HEWL) and the antifibril-forming activity of myricetin were investigated. We demonstrate
that myricetin significantly inhibits the fibrillation of HEWL and the inhibitory effect is dose-dependent. Interestingly, the
inhibitory effect toward HEWL fibrillation was stronger than that exerted by the previously characterized fibril-forming inhibitor
quercetin, which has high structural similarity with myricetin. Spectrofluorometric and computational studies suggest that the
mechanism underlying the inhibitory action of myricetin at a molecular level is to reduce the population of partially unfolded
HEWL intermediates. This action is achieved by the tight binding of myricetin to the aggregation-prone region of the β-domain
of HEWL and linking to the relatively stable α-domain, thus resulting in the inhibition of amyloid fibril formation