70 research outputs found
On the Basics of Biochemistry (An edited and shortened version of the presentation given on 12 September 2012 in the 10th semester of the Open University of Szeged)
Modification of the IFCC reference measurement procedure for determination of HbA1c by HPLC-ESI-MS
The reference measurement procedure for determination of HbA1c (glycated haemoglobin) using HPLC(high performance liquid chromatography)-ESI(electrospray ionisation)-MS(mass spectrometry) has been modified. Main modifications were a change in the buffer composition of the HPLC, a change in the gradient elution profile and the introduction of a post-column splitting system. The long-term stability of the HPLC-ESI-MS system proved to be of high importance to get reproducible results
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