Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Manufacture of the ITER Central Solenoid Components

The ITER central solenoid (CS) components are currently being manufactured. This Nb$_{3}$Sn superconducting magnet will provide the magnetic flux swing required to induce up to 15 MA as plasma current. It includes six identical coils, called modules, stacked on top of each other to form a solenoid, enclosed inside a structure split into nine subsets, to provide vertical precompression and mechanical support. High mechanical stresses in materials and high voltages call for the use of structural materials with high strength and toughness and high dielectric strength insulating materials, respectively. The pulsed operation imposes materials with high fatigue strength at cryogenic temperatures. Unlike for the structure, where large existing manufacturing tools were usable, the modules required the construction of a dedicated manufacturing line. A comprehensive qualification programme is performed at the manufacturers before applying procedures for the production of the CS components. The main characteristics of the CS components, their manufacturing routes and the different elements of the qualification programme are described. The overall plan for the manufacture is reported. The status of the first series production components manufactured is presented as well as the planned delivery schedule to the ITER site

swcarpentry/shell-novice: Software Carpentry: the UNIX shell, June 2019

Software Carpentry lesson on how to use the shell to navigate the filesystem and write simple loops and scripts