23 research outputs found
People Ex. Rel. Scott v. Briceland: Powers of the Attorney General Revisited, 11 J. Marshall J. Prac. & Proc. 441 (1978)
status: Published onlin
DS-MS-TCN: Otago Exercises Recognition with a Dual-Scale Multi-Stage Temporal Convolutional Network
The Otago Exercise Program (OEP) represents a crucial rehabilitation
initiative tailored for older adults, aimed at enhancing balance and strength.
Despite previous efforts utilizing wearable sensors for OEP recognition,
existing studies have exhibited limitations in terms of accuracy and
robustness. This study addresses these limitations by employing a single
waist-mounted Inertial Measurement Unit (IMU) to recognize OEP exercises among
community-dwelling older adults in their daily lives. A cohort of 36 older
adults participated in laboratory settings, supplemented by an additional 7
older adults recruited for at-home assessments. The study proposes a Dual-Scale
Multi-Stage Temporal Convolutional Network (DS-MS-TCN) designed for two-level
sequence-to-sequence classification, incorporating them in one loss function.
In the first stage, the model focuses on recognizing each repetition of the
exercises (micro labels). Subsequent stages extend the recognition to encompass
the complete range of exercises (macro labels). The DS-MS-TCN model surpasses
existing state-of-the-art deep learning models, achieving f1-scores exceeding
80% and Intersection over Union (IoU) f1-scores surpassing 60% for all four
exercises evaluated. Notably, the model outperforms the prior study utilizing
the sliding window technique, eliminating the need for post-processing stages
and window size tuning. To our knowledge, we are the first to present a novel
perspective on enhancing Human Activity Recognition (HAR) systems through the
recognition of each repetition of activities
Otago Exercises Monitoring for Older Adults by a Single IMU and Hierarchical Machine Learning Models
Otago Exercise Program (OEP) is a rehabilitation program for older adults to
improve frailty, sarcopenia, and balance. Accurate monitoring of patient
involvement in OEP is challenging, as self-reports (diaries) are often
unreliable. With the development of wearable sensors, Human Activity
Recognition (HAR) systems using wearable sensors have revolutionized
healthcare. However, their usage for OEP still shows limited performance. The
objective of this study is to build an unobtrusive and accurate system to
monitor OEP for older adults. Data was collected from older adults wearing a
single waist-mounted Inertial Measurement Unit (IMU). Two datasets were
collected, one in a laboratory setting, and one at the homes of the patients. A
hierarchical system is proposed with two stages: 1) using a deep learning model
to recognize whether the patients are performing OEP or activities of daily
life (ADLs) using a 10-minute sliding window; 2) based on stage 1, using a
6-second sliding window to recognize the OEP sub-classes performed. The results
showed that in stage 1, OEP could be recognized with window-wise f1-scores over
0.95 and Intersection-over-Union (IoU) f1-scores over 0.85 for both datasets.
In stage 2, for the home scenario, four activities could be recognized with
f1-scores over 0.8: ankle plantarflexors, abdominal muscles, knee bends, and
sit-to-stand. The results showed the potential of monitoring the compliance of
OEP using a single IMU in daily life. Also, some OEP sub-classes are possible
to be recognized for further analysis.Comment: 10 page
Inflammatory markers are associated with quality of life, physical activity, and gait speed but not sarcopenia in aged men (40-79Â years)
Background: Age-related chronic low-grade inflammation (inflammaging) is one of the proposed mechanisms behind sarcopenia. However, findings regarding inflammatory markers in sarcopenic older adults are conflicting. This study aimed to determine the association between inflammatory markers, prevalent as well as incident sarcopenia, sarcopenia-defining parameters, quality of life (QoL), and physical activity in middle-aged and older men. Methods: Men aged 40–79 years (mean 59.66 ± 11.00y) were recruited from population registers in eight European centres for participation in the European Male Aging study (EMAS). Subjects were assessed at baseline (2003–2005) and again after a median follow-up of 4.29 years. In 2577 participants, associations between baseline inflammatory markers [high-sensitive C-reactive protein (hs-CRP), white blood cell count (WBC), albumin] and baseline physical activity (PASE) and QoL (SF-36) were analysed. In the Leuven and Manchester cohort (n = 447), data were available on muscle mass (whole-body dual X-ray absorptiometry) and strength. In this subgroup, cross-sectional associations between baseline inflammatory markers and sarcopenia-defining parameters (handgrip strength, chair stand test, appendicular lean mass, and gait speed) and prevalent sarcopenia were examined. In a further subgroup (n = 277), associations with knee extensor strength were explored. Longitudinally, predictive value of baseline inflammation on functional decline, physical activity, QoL, and incident sarcopenia was examined. Subgroup analyses were performed in subgroups with chronic inflammation and stratified by age. Linear and logistic regressions were used, adjusted for age, body mass index, centre, and smoking. Results: At baseline, hs-CRP and WBC were negatively associated with PASE score (hs-CRP: β = −7.920, P < 0.001; and WBC: β = −4.552, P < 0.001) and the physical component score of SF-36 (hs-CRP: β = −1.025, P < 0.001; and WBC: β = −0.364, P < 0.001). Baseline WBC levels were negatively associated with gait speed (β = −0.013; P = 0.025), quadriceps isometric 90° (β = −5.983; P = 0.035) and isokinetic 60°/s peak torque/body weight (β = −5.532; P = 0.027). The prevalence of sarcopenia at baseline was 18.1% (n = 81). Of those without sarcopenia at baseline, 64 (18.6%) satisfied criteria for sarcopenia at follow-up. There were no significant associations between baseline inflammatory markers and either prevalent or incident sarcopenia, or change in level of sarcopenia-defining parameters between baseline and follow-up. Conclusions: In middle-aged and older men, hs-CRP and WBC were negatively associated with QoL and PASE scores, while WBC was negatively associated with gait speed and knee strength. Associations with hs-CRP remained significant in all ages, whereas WBC levels were only associated with PASE, gait speed and knee strength in older adults (60–79 years). Baseline inflammatory markers (hs-CRP, WBC and albumin) did not predict functional decline, decline in physical activity, decreased QoL or incident sarcopenia
Inflammatory markers are associated with quality of life, physical activity, and gait speed but not sarcopenia in aged men (40-79 years)
Background Age-related chronic low-grade inflammation (inflammaging) is one of the proposed mechanisms behind sarcopenia. However, findings regarding inflammatory markers in sarcopenic older adults are conflicting. This study aimed to determine the association between inflammatory markers, prevalent as well as incident sarcopenia, sarcopenia-defining parameters, quality of life (QoL), and physical activity in middle-aged and older men. Methods Men aged 40-79 years (mean 59.66 +/- 11.00y) were recruited from population registers in eight European centres for participation in the European Male Aging study (EMAS). Subjects were assessed at baseline (2003-2005) and again after a median follow-up of 4.29 years. In 2577 participants, associations between baseline inflammatory markers [high-sensitive C-reactive protein (hs-CRP), white blood cell count (WBC), albumin] and baseline physical activity (PASE) and QoL (SF-36) were analysed. In the Leuven and Manchester cohort (n = 447), data were available on muscle mass (whole-body dual X-ray absorptiometry) and strength. In this subgroup, cross-sectional associations between baseline inflammatory markers and sarcopenia-defining parameters (handgrip strength, chair stand test, appendicular lean mass, and gait speed) and prevalent sarcopenia were examined. In a further subgroup (n = 277), associations with knee extensor strength were explored. Longitudinally, predictive value of baseline inflammation on functional decline, physical activity, QoL, and incident sarcopenia was examined. Subgroup analyses were performed in subgroups with chronic inflammation and stratified by age. Linear and logistic regressions were used, adjusted for age, body mass index, centre, and smoking. Results At baseline, hs-CRP and WBC were negatively associated with PASE score (hs-CRP: beta = -7.920, P Conclusions In middle-aged and older men, hs-CRP and WBC were negatively associated with QoL and PASE scores, while WBC was negatively associated with gait speed and knee strength. Associations with hs-CRP remained significant in all ages, whereas WBC levels were only associated with PASE, gait speed and knee strength in older adults (60-79 years). Baseline inflammatory markers (hs-CRP, WBC and albumin) did not predict functional decline, decline in physical activity, decreased QoL or incident sarcopenia.</p
Does Parkinson’s Disease or Sarcopenia Underlie the Motor Unit Deficits in Patients with Parkinsonian Syndromes?
status: Published onlin