References of Birth Weights for Gestational Age and Sex from a Large Cohort of Singleton Births in Cameroon

Objective. To establish the percentile charts of birth weights for gestational age and sex within the Cameroonian population. Methods. A review of medical records of infants born between January 2007 and December 2011 at the maternities of two hospitals in Cameroon, Central Africa. Multiple pregnancies, births of HIV infected women, stillbirths, and births with major fetal malformations were excluded. The smooth curves of birth weight for gestational age and sex were created using the Gamlss package under R.3.0.1 software. Results. The birth weights of 12837 live birth singleton infants born to HIV negative women between 28 and 42 weeks of gestation were analyzed to construct the birth weight curves for gestational age and sex. The smoothed percentile curves of birth weights for gestational age and sex of Cameroonian infants have demonstrated an increasing slope until 40 weeks and then a plateau. There was a varied difference of distribution in birth weights for gestational age between Cameroonian, Botswanan, American, and French infants. Conclusion. We established the reference curves of birth weights for gestational age and sex for Cameroonians. The difference in birth weight curves noted between Cameroonian, Botswanan, American, and French infants suggests the importance of establishing the regional birth weight norms

Childbirth patterns after previous caesarean birth in sub-Saharan Africa: a retrospective analytical study in two referral hospitals in a semi-urban setting in Cameroon

Background: Rising rates of caesarean section (CS) predispose to uterine rupture (UR) during subsequent childbirths. Childbirth after previous CS has poorly been studied in rural Africa. Objective was to describe and analyse the patterns of childbirths after previous CS.Methods: A retrospective analytical study of facility-based deliveries after previous caesarean birth from January 1, 2019 to April 30, 2021 in Bafoussam, Cameroon. We included 416 files of women with previous CS for term singleton pregnancies. Statistics were computed with SPSS®.Results: Mean age and mean parity were 29.9±5.6 years and 3.2±1.4 respectively. Almost half of participants [199 (47.8%)] had had a previous vaginal birth. Antenatal care (ANC) providers were nurses/midwives and general practitioners for 232 (55.8%) and 77 (18.5%) women respectively. The route of delivery wasn’t chosen during ANC for 312 (75.0%) women and 99 (23.8%) of participants were referred during labour. Elective repeat CS was done for 92 (22.1%) women and 324 (77.9%) underwent trial of labour after CS (TOLAC) of whom 131 (40.4%) gave birth by vaginal route. Onset of labour was spontaneous in 304 (93.8%) cases. UR complicated 13 (4.0%) cases of TOLAC. Previous vaginal birth predicted successful TOLAC and referred parturients had higher risk of UR. There were 28 (8.6%) perinatal deaths and 1 (0.3%) maternal death.Conclusions: In our semi urban setting, deliveries after previous caesarean births are unplanned. The success rate of TOLAC is low with a high rate of complications. There is need to improve quality of ANC, birth care and post-natal care for women with previous CS

Pitfalls in Diagnosing Heterotopic Pregnancy in Sub-Saharan Africa: A Case Report at the Yaounde University Teaching Hospital (Cameroon).

Heterotopic pregnancy (HP) is a dizygotic twin pregnancy in which one gestational sac is intrauterine and the other is extrauterine. The prevalence of HP is unknown in Cameroon where the diagnosis is difficult and usually fortuitous like in other resource-poor settings. We herein depict pitfalls and delays in the diagnosis and management of a ruptured heterotopic pregnancy at the Yaounde University Teaching Hospital. After a wrong diagnosis and inadequate treatment, our patient presented at our emergency unit with severe pelvic pain and clinical signs of hemoperitoneum with shock. She underwent a total left salpingectomy through laparotomy. She had a complete spontaneous abortion five days after the surgery. Given that sonography is not routinely available in emergency departments in resource-poor settings, it may be relevant for practitioners to always bear HP in mind when facing ruptured ectopic pregnancies

Prevalence and phenotypic features of polycystic ovary syndrome among patients attending gynaecology clinic in two referral hospitals in Yaoundé, Cameroon

Background: Polycystic ovary syndrome (PCOS) is a common gynaecological endocrine disease in women at reproductive age. This study aimed to determine the prevalence and phenotypes of PCOS among women attending gynecology clinic at the two referral hospitals in Yaoundé.Methods: It was a cross sectional retrospective study involving women attending the gynecology clinic of two referral hospitals in Yaoundé, Cameroon from January 2016 to March 2018. The socio-demographic information, clinical and laboratory characteristics of each patient were collected from the medical files.Results: A total of 143 patients diagnosed with PCOS were included. The prevalence of PCOS was estimated at 3.5%. The mean age of patients was 29.18±4.5 years with a range of 17 to 41 years. Most patients were either overweight (31.7%) or obese (43%) and 0.7% patients were underweight. The most frequent presentations of PCOS patients were infertility (74.1%), oligomenorrhea/amenorrhea (68.5%), hirsutism (62,9%) and acne (20.3%). The different phenotypes represented were classical phenotype A: 69% (99/143), phenotype B: 17% (24/143), phenotype C: 09% (13/143) and phenotype D: 05% (07/143). Medical treatment (76.9%) and general measures (23.1%) were the most frequent therapeutic options among PCOS patients. In vitro fertilization (08.4%) and surgical drilling (07%) was also used.Conclusions: Prevalence of PCOS in our setting is 3.5%. The classical phenotype A is the most common. It is important to think about PCOS in women attending gynecology clinic

The Relationship between Adiposity and Insulin Sensitivity in African Women Living with the Polycystic Ovarian Syndrome: A Clamp Study

Objectives. We aimed to assess the variation of insulin sensitivity in relation to obesity in women living with PCOS in a sub-Sahara African setting. Methods. We studied body composition, insulin sensitivity, and resting energy expenditure in 14 PCOS patients (6 obese and 8 nonobese) compared to 10 matched nonobese non-PCOS subjects. Insulin sensitivity was assessed using the gold standard 80 mU/m2/min euglycemic-hyperinsulinemic clamp and resting energy expenditure was measured by indirect calorimetry. Results. Insulin sensitivity adjusted to lean mass was lowest in obese PCOS subjects and highest in healthy subjects (11.2 [10.1–12.4] versus 12.9 [12.1–13.8] versus 16.6 [13.8–17.9], p=0.012); there was a tendency for resting energy expenditure adjusted for total body mass to decrease across the groups highest in obese PCOS subjects (1411 [1368–1613] versus 1274 [1174–1355] versus 1239 [1195–1454], p=0.306). Conclusion. In this sub-Saharan population, insulin resistance is associated with PCOS per se but is further aggravated by obesity. Obesity did not seem to be explained by low resting energy expenditure suggesting that dietary intake may be a determinant of the obesity in this context

A freaky motorbike accident causing vulvar hematoma: a case report at the Bafoussam Regional Hospital, West-Cameroon

Non-obstetric vulvar hematomas are rare and have never been reported in West Cameroon. No guidelines are available to inform the management of cases. Authors herein report the successful management of a post-traumatic vulvar hematoma in a 17 years old gravida 1 para 1001 patient. She was referred to our emergency department ten hours after a fall in a squatting position during a road traffic accident. Prior to the referral she had been managed conservatively by analgesics and a compressive dressing of the vulva in a community clinic. Clinical assessment on admission revealed a good general condition, normal vital signs and a tense and painful hematoma of the right labia. Surgery was done under general anesthesia to drain the hematoma, ligate the bleeding vessels and repair the vulva. Post-operative course was uneventful and the patient was discharge six days later. This case reminds practitioners in remote health facilities that early referral of this rare pathology contributes to its successful surgical management in our semi-urban region