A GIS-based hydrographic resurvey strategy of the Belgian Continental Shelf

Using a GIS-based approach, bathymetric surveys and maritime traffic records were combined to determine resurvey priorities within the Belgian Continental Shelf (BCS). Four reference layers were produced: (1) water depth; (2) maximum absolute change in water depth; (3) ship traffic intensity; (4) maximum ship draught. The reference layers were reclassified and merged into a weighted overlay analysis. Two combinations of layers and weight factors were used and resulted in priority maps differing greatly from each other. The reliability of the analysis depends on the way weight factors are assigned, and on the availability and accuracy of the data. These are limited for bathymetric surveys. This empirical GIS-based methodology can be applied as a whole to a zone showing various morphodynamic patterns. It can also be automated: additional datasets can be included in the analysis, and different scenarios and assumptions can be easily tested

Signal processing with silicon-organic hybrid waveguides

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100 Gbit/s electro-optic modulator and 56 Gbits/s wavelength converter for DQPSK data in silicon-organic hybrid (SOH) technology

CMOS-compatible silicon photonics combined with covers of chi (2) or chi (3)-nonlinear organic material allows electro-optic modulators and all-optical wavelength converters for data rates of 100 Gbit/s and beyond. The devices are not impaired by free carriers

FHIT gene therapy prevents tumor development in Fhit-deficient mice

The tumor suppressor gene FHIT spans a common fragile site and is highly susceptible to environmental carcinogens. FHIT inactivation and loss of expression is found in a large fraction of premaligant and malignant lesions. In this study, we were able to inhibit tumor development by oral gene transfer, using adenoviral or adenoassociated viral vectors expressing the human FHIT gene, in heterozygous Fhit+/- knockout mice, that are prone to tumor development after carcinogen exposure. We therefore suggest that FHIT gene therapy could be a novel clinical approach not only in treatment of early stages of cancer, but also in prevention of human cancer

Intrathoracic fire during preparation of the left internal thoracic artery for coronary artery bypass grafting

A surgical fire is a serious complication not previously described in the literature with regard to the thoracic cavity. We report a case in which an intrathoracic fire developed following an air leak combined with high pressure oxygen ventilation in a patient with severe chronic obstructive pulmonary disease. The patient presented to our institution with diffuse coronary artery disease and angina pectoris. He was treated with coronary artery bypass graft surgery, including left internal thoracic artery harvesting. Additionally to this rare presentation of an intrathoracic fire, a brief review of surgical fires is included to this paper

Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells

SCOPUS: ar.jinfo:eu-repo/semantics/publishe