4 research outputs found
Olfactory bulb serotonin level modulates olfactory recognition in neonate rat
1078-1082Role of serotonin in olfactory recognition
was tested by depleting the olfactory bulb serotonin during postnatal day
(PND)1- 4 following administration of 5,7-dihydroxytryptamine. Significant
difference in the olfactory recognition test was observed during PND5-7;
control pups successfully recognized and oriented towards their mother; whereas
treated pups failed to recognize their mother odour. Later on, during PND12-14,
both group of pups responded equally in the recognition test. Levels of
olfactory bulb serotonin were depleted (53.3%) in the treated pups on PND-8,
which was restored on PND-14 with only 15% variation. Further analysis
demonstrated that depletion of serotonin in olfactory bulb did not affect the
normal suckling and weight gain, it only modulates olfactory recognition