157 research outputs found

    Analysis of priority sectors of the economy in the policy of import substitution

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    In this paper, the authors considered the priority sectors of the economy in the policy of import substitution. Analyses were carried outthe work of foreign and domestic scientistproposed the author's interpretation of the import substitution policy, presentedthe scheme of work of the industry of import substitution in the Russian Federatio

    Assessment of the industrial enterprises competitiveness in terms of import placement

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    The article describes a method to estimate the industrial enterprises’ competitiveness in the modern conditions of the import substitution policy’s application by the governing bodies of the Russian Federation. In this paper, the authors consider the factors and principles of the enterprise’s competitiveness. The authors have represented several approaches for the competitiveness assessment, and after that the most suitable one to assess the competitiveness of the industrial enterprises in the changing external environment, namely the application of the import substitution policy is chosen. For a detailed study of the concept of the «import substitution», the authors have reviewed the foreign countries’ experience concerning the import substitution policy application. As a result, the advantages and disadvantages of this policy, and especially the impact on the national economy, have been found out. The authors have also taken into account the social component of the assessment of the company’s competitiveness, which is currently one of the important indicators of industrial enterprises. The authors propose their mechanism of improving competitiveness of industrial enterprises in the conditions of import substitutio

    COMPARATIVE CHARACTERIZATION OF THE MACROORGANISM IMMUNE RESPONSE AFTER PERORAL AND PARENTERAL INTRODUCTION OF METALLIC NANOCOMPOSITE

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    Influence of a cobalt-containing nanobiocomposite on basis of arabinogalactane on morphological changes in immunocompetent organs of the experimental animals at peroral and parenteral introduction was studied, by a computer program. «Morphometry». Comparative estimation, of morphological and. histological changes in spleen and. regional lymph, nodes of the outbred. white mice was performed

    Synthesis of pure hydroxyapatite by ion exchange reaction

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    An ion-exchange reaction for the synthesis of hydroxyapatite (HAP) in a constant alkaline medium using preliminary dry homogenization is proposed in this work. Sodium hydrogen phosphate Na2HPO4, calcium chloride CaCl2 and calcium hydroxide Ca(OH)2 were chosen as precursors. Studies carried out by methods of X-ray phase analysis, scanning electron and transmission microscopy showed that the material obtained is a singlephase hydroxyapatite powder with a Ca/P ratio close to 1.67. It was found that the particles of HAP powder obtained as a result of synthesis with subsequent washing have the shape of needles with a thickness of 10 to 40 nm and a length of 30 to 200 nm. Annealing of the powder at a temperature of 700 °C leads to agglomeration of particles, as well as to rounding of their shap

    ESTIMATION OF INFLUENCE OF ARGENTOGALACTOMANNAN AND ARGENTO-POLY-1-VINYL-1,2,4-TRIAZOLE ON POPULATION STRUCTURE OF RED MARROW CELLS OF EXPERIMENTAL ANIMALS

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    We studied influence of silver-containing nanocomposites — galactomannan and poly-1-vinyl-1,2,4-triazole — on cell structure of peripheral blood and red marrow of white mice. The results obtained after the experiments testify that these nanocomposites aren't toxic, the changes caused by their introduction are productive and. part of them points at the activization of immune system of macroorganizm

    INFLUENCE OF BRUCELLA ABORTUS I-206 THERMOEXTRACTS IN L- AND S-FORM ON MORPHOFUNCTIONAL STATE OF WHITE MICE ADRENAL GLANDS

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    Live vaccines are used for specific brucellosis prophylaxis in the Russian Federation. These vaccines in addition to a number of  positive properties have some limitations including high  agglutinogenicity, reactogenicity, sensitizing activity. In this  connection, the development of subunit vaccines without adverse  reactions is a perspective direction in modern vaccinology. Complex  morphological research of the adrenal glands and comparative  analysis of peripheral blood (leukogram, leukocytic index and index  of allergization) of white mice immunized with thermoextracts (ТE)  of Brucella abortus I-206 in L- and S-form and inactivated vaccine B.  abortus 19 ВА were conducted. It was shown that ТE unlike B.  abortus 19 ВА caused minor alterations in peripheral blood of the  experimental animals in early periods of observation (increase of allergization index, changes in leukogram) with the subsequent  levelling to the values in control. Expositions of the adrenal gland  zoning were determined and cellular structure was estimated in  consideration of morphometry. Changes in architectonics of the mice  organ immunized with B. abortus 19 ВА were revealed. These alterations could indicate the stress-reaction development. In  case of ТE application the given changes were insignificant and were  developed in early periods. The revealed morphological changes in  adrenal glands of laboratory animals permit to prove the necessity of  realization the further experimental researches to ТE application  as the components for development of a subcellular brucellosis vaccine
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