COVID-19 in Pregnant Women With Rheumatic Disease: Data From the COVID-19 Global Rheumatology Alliance

OBJECTIVE: To describe coronavirus disease-2019 (COVID-19) and pregnancy outcomes in patients with rheumatic disease who were pregnant at the time of infection. METHODS: Since March 2020 the COVID-19 Global Rheumatology Alliance (GRA) has collected cases of patients with rheumatic disease with COVID-19. We report details of pregnant women at the time of COVID-19 infection, including obstetric details separately ascertained from providers. RESULTS: We report on 39 patients, including 22 with obstetric detail available. The mean and median age was 33 years, range 24-45 years. Rheumatic disease diagnoses included: rheumatoid arthritis (n=9), systemic lupus erythematosus (n=9), psoriatic/other inflammatory arthritides (n=8) and anti-phospholipid antibody syndrome (n=6). Most had a term birth (16/22), with 3 pre-term births, one termination, one miscarriage and one woman yet to deliver at time of report. A quarter (n=10/39) of pregnant women were hospitalised following COVID-19 diagnosis. Two of 39 (5%) required supplemental oxygen (both hospitalised); no patient died. The majority did not receive specific medication treatment for their COVID-19 (n=32/39, 82%), seven patients received some combination of anti-malarials, colchicine, anti-IL-1beta, azithromycin, glucocorticoids, and lopinavir/ritonavir. CONCLUSION: Women with rheumatic diseases who were pregnant at the time of COVID-19 had favourable outcomes. These data have limitations due to the small size and methodology, though they provide cautious optimism for pregnancy outcomes for women with rheumatic disease given the increased risk of poor outcomes that have been reported in other series of pregnant women with COVID-19

Flow-by-flow chemical stratigraphy and evolution of thirteen Serra Geral Group basalt flows from Vista Alegre, southernmost Brazil

The geochemical characterization of thirteen Serra Geral Group flows in the Vista Alegre region (RS-SC), southern Brazil, displays the homogeneous basaltic composition near 50 wt.% SiO2. Each of the five basal flows (Pitanga-type, high-Ti/Y ~600, TiO2 > 3 wt.%) and eight upper flows (Paranapanema-type, medium Ti/Y ~400, TiO2 > 2 wt.%) can be identified from their chemical composition; sets of flows have parallel variation in chemical composition. The flow-by-flowcorrelation in four sections shows the horizontal position of the flows in three profiles and an approximately 200-m downdrop of the Itapiranga block with respect to the Frederico Westphalen block. The world-class amethyst geode mineralization and the systematic presence of native copper in the basalts make the correlation of great geological and economic significance.<br>A caracterização geoquímica de treze derrames do Grupo Serra Geral na região de Vista Alegre (RS e SC), sul do Brasil, exibe uma composição basáltica homogênea próxima a 50% de SiO2. Os cinco derrames basais são classificados quimicamente como tipo Pitanga (alto Ti/Y ~600 e TiO2 > 3 em peso percentual), os demais oito derrames possuem médio Ti/Y ~400 com TiO2 ~2.5 em peso percentual, sendo classificados como magma tipo Paranapanema. Cada derrame pode ser identificado através de sua composição química e correlacionado, com variação paralela entre os perfis estudados. A correlação derrame a derrame nos quatro perfis demonstra uma posição horizontal em três perfis e um rejeito vertical de aproximadamente 200 m do bloco Itapiranga em relação ao bloco Frederico Westphalen. A presença de jazidas de ametista em geodos e a sistemática ocorrência de cobre nativo nos basaltos da região tornam a correlação de grande significado geológico e econômico

Associação entre comportamentos de risco à saúde de pais e adolescentes em escolares de zona rural de um município do Sul do Brasil Association between health risk behaviors in parents and adolescents in a rural area in southern Brazil

Objetivou-se avaliar a associação entre comportamentos de risco à saúde dos pais e adolescentes escolares de zona rural. Participaram 377 escolares entre 10 e 18 anos e 338 pais. Foram analisados: nível de atividade física no lazer e deslocamento, hábitos de alimentação inadequados, excesso de peso, uso de cigarros e consumo de bebidas alcoólicas. A prevalência de relato de uso de cigarro e álcool nos últimos 30 dias entre os jovens foi de 6,7% e 27%, respectivamente. Quarenta e cinco por cento dos adolescentes não atingiram o escore de atividade física. A adesão aos passos para uma alimentação saudável foi baixa. A atividade física dos adolescentes esteve relacionada de forma positiva com a dos pais, e o consumo de álcool da mãe se associou de forma positiva com o consumo do adolescente. Para os outros comportamentos, não houve associação significativa. Na análise estratificada por sexo, o nível de atividade física do pai se associou ao nível de atividade física das meninas. O comportamento de risco à saúde dos pais associa-se ao mesmo comportamento dos adolescentes de zona rural.<br>This article aimed to assess the association between health risk behaviors in parents and adolescents in a rural area. The sample included 377 schoolchildren 10 to 18 years of age and 338 parents. The following variables were analyzed: level of leisure-time and commuting physical activity, inadequate eating habits, overweight/obesity, smoking, and alcohol consumption. Prevalence rates for smoking and alcohol consumption by adolescents in the previous 30 days were 6.7% and 27%, respectively. Forty-five percent of adolescents failed to reach the target physical activity score. Adherence to steps to healthy eating was low. Physical activity in adolescents was positively associated with that of parents, and adolescent drinking was associated with maternal alcohol consumption. There was no significant association for other behaviors. In the analysis stratified by gender, level of physical exercise in female adolescents was associated with that of fathers. Parental health risk behaviors were associated with the behaviors in the adolescent children in this rural area