TLC Separation of Closely Related Amino Acids

761-76

Mineral content of red skinned potatoes of Eastern India

Potato tuber colour is an important factor that influences consumer preferences. Eastern plain region of India contributes about 50% of total potato acreage and production. Consumers in this region generally prefer red skinned varieties. Growing awareness for nutrient rich food can create a niche market for nutritious potatoes. Potato is crop of choice for mineral biofortification owing to better mineral bioavailability due to its high ascorbic acid and minimal phytate content. Iron and zinc are the essentially required minerals for good health. Considering the nutritional importance of these elements and wider prevalence of their deficiency in Indian sub-continent, thirteen Eastern regions red skinned advanced hybrids and varieties were evaluated to find the genetic diversity for iron and zinc content. A significant wide range of contents was observed for both the elements. High heritability of both mineral suggests feasibility of selecting genotypes for breeding nutrient rich varieties. Identified genotypes can be utilised as parental lines for future breeding programme and can be released as nutrient rich potato variety

3D-printing: An emerging and a revolutionary technology in pharmaceuticals

© 2018 EDIZIONI MINERVA MEDICA. One of the novel and progressive technology employed in pharmaceutical manufacturing, design of medical device and tissue engineering is three-dimensional (3D) printing. 3D printing technologies provide great advantages in 3D scaffolds fabrication over traditional methods in the control of pore size, porosity, and interconnectivity. Various techniques of 3D-printing include powder bed fusion, fused deposition modeling, binder deposition, inkjet printing, photopolymerization and many others which are still evolving. 3D-printing technique been employed in developing immediate release products, various systems to deliver multiple release modalities etc. 3D printing has opened the door for new generation of customized drug delivery with built-in flexibility for safer and effective therapy. Our mini-review provides a quick snapshot on an overview of 3D printing, various techniques employed, applications and its advancements in pharmaceutical sciences

Titanyl (IV), Zirconyl (IV), Hafnyl (IV) and Uranyl (VI) Complexes of Terdentate Benzoyl Hydrazones

Titanyl(IV), zixconyl(!V), hafnyl(IV) and uranyl(Vl) oomplexes of beniz\u27Dyl hydrazones derti.ved frnm benzoyl hymazdne and sal1cyla1dehyde (BSH), o-hydro!XY acetopheilOllle (BAH), o-hydroxy propi0tphenone (BPH) and 2-hydroxy-1-naphthaldehyde (BNH) are desc·ribed. These complexes were characterised on the basis oof elemental analyses, electrical conductance and spectral (IR, UV and visible) data. The tiltany1\u27(!V) complexes having ·the formula [TiL(OH) (H20) lzO appear ·to have a seven- coordinat·e geometry, the zirconyl and hafnyl complexes, [ML(OHh(H20) )4 (M = Zr or HO appear to possess tetrameric structure in which each metal atom is e.ight-coordina:ted as in the origin,aJl salt, MOCh.8H20 (M = Zr or Hf) ; whereas uranyl comple·xes [UO:J.;(H20hh are dimeric having phenoxide brlidges, •tiu/°\u27u•ti as revealed by the \u27-o,, r:in:g v~br.ations in the IR spectra at ca. 845 cm-1, wi.th each metal atom having an eightcoordinated structure. In all these complexes the benzoyl hydrazones act as di!ba:sic te1r.dentate (N, o-. o-> chelating agentJs

Development of Word Associations in a Second Language

Proceedings of the Ninth Annual Meeting of the Berkeley Linguistics Society (1983), pp. 202-21

Assessment of Acute Oral Toxicity of Thiolated Gum Ghatti in Rats

Various drug delivery systems were developed using a modified form of gum ghatti. Modifying gum ghatti using thioglycolic acid improves its mucoadhesive property, and hence, it is a suitable approach for the fabrication and development of controlled drug delivery systems. In accordance with regulatory guidelines, namely, the Organization for Economic Co-operation and Development’s (OECD) 423 guidelines, an acute oral dose toxicity study was performed to examine the toxicological effects of gum ghattiin an animal (Wistar rat) after a single oral dose administration of pure gum ghatti and thiolated gum ghatti. Orally administered pure and thiolated gum ghatti do not reveal any considerable change in the behavioral pattern, food intake, body weight, hematology, or clinical symptoms of treated animals. Furthermore, histopathological studies showed no pathological mutations in the vital organs of Wistar rats after the oral administration of single doses of both types of gumghatti (i.e., 300 mg/kg and 2000 mg/kg body weight). Whole blood clotting studies showed the low absorbance value of the modified gum (thiolated gum ghatti) in contrast to the pure gum and control, hence demonstrating its excellent clotting capability. The aforementioned toxicological study suggested that the oral administration of a single dose of pure and thiolated gum ghatti did not produce any toxicological effects in Wistar rats. Consequently, it could be a suitable and safe candidate for formulating various drug delivery systems.</jats:p

Eccentric lamellar keratolimbal grafts harvested with a manually guided microkeratome

Background: To perform lamellar keratolimbal allograft transplantation in a one- step procedure with a single graft, we investigated the feasibility of harvesting eccentric lamellar keratolimbal grafts from conventionally processed corneoscleral buttons using a manually guided microkeratome in conjunction with an artificial anterior chamber system. Methods: We used the Moria LSK- One microkeratome and the automated lamellar therapeutic keratoplasty ( ALTK) system ( Antony, France). Ten human donor eyes were used to obtain single- piece lamellar keratolimbal grafts. Specimens were processed for light and electron microscopy. Results: Eccentric keratolimbal grafts could be obtained from all human donor buttons. Grafts include a crescent- shaped limbal and a large corneal portion. No visible damage to the limbal region was discernible. Conclusion: Our data show that the LSK- One microkeratome in conjunction with the ALTK system allows harvesting eccentric keratolimbal grafts from donor corneoscleral buttons. Copyright (c) 2007 S. Karger AG, Basel