11 research outputs found
Maleimide-Functionalized Photochromic Spirodihydroindolizines
Two photochromic spirodihydroindolizine/betaine systems
for tethering
to peptides and proteins via a maleimide function have been prepared.
The absorption spectra of the betaines are in the red region of the
visible spectrum and in the near-IR spectral domain, which are suitable
energies of light for future in vivo applications. The half-times
of cyclization have been determined for both DHI/betaine systems.
The findings are consistent with a thermal barrier of varying size
between the <i>transoid</i> and <i>cisoid</i> conformers
of the betaines