A Pairwise Key Pre-Distribution Scheme for Wireless Sensor Networks

This paper, we provide a framework in which to study the security of key pre-distribution schemes, propose a new key pre-distribution scheme which substantially improves the resilience of the network compared to previous schemes, and give an in-depth analysis of our scheme in terms of network resilience and associated overhead. Our scheme exhibits a nice threshold property: when the number of compromised nodes is less than the threshold, the probability that communications between any additional nodes are compromised is close to zero. This desirable property lowers the initial payoff of smaller-scale network breaches to an adversary, and makes it necessary for the adversary to attack a large fraction of the network before it can achieve any significant gain

Attack-resistant location estimation in wireless sensor networks

Many sensor network applications require sensors’ locations to function correctly. Despite the recent advances, location discovery for sensor networks in hostile environments has been mostly overlooked. Most of the existing localization protocols for sensor networks are vulnerable in hostile environments. The security of location discovery can certainly be enhanced by authentication. However, the possible node compromises and the fact that location determination uses certain physical features (e.g., received signal strength) of radio signals make authentication not as effective as in traditional security applications. This paper presents two methods to tolerate malicious attacks against range-based location discovery in sensor networks. The first method filters out malicious beacon signals on the basis of the “consistency” among multiple beacon signals, while the second method tolerates malicious beacon signals by adopting an iteratively refined voting scheme. Both methods can survive malicious attacks even if the attacks bypass authentication, provided that the benign beacon signals constitute the majority of the beacon signals. This paper also presents the implementation and experimental evaluation (through both field experiments and simulation) of all the secure and resilient location estimation schemes that can be used on the current generation of sensor platforms (e.g., MICA series of motes), including the techniques proposed in this paper, in a network of MICAz motes. The experimental results demonstrate the effectiveness of the proposed methods, and also give the secure and resilient location estimation scheme most suitable for the current generation of sensor networks

Attack-Resistant Location Estimation in Sensor Networks

Many sensor network applications require sensors ’ locations to function correctly. Despite the recent advances, location discovery for sensor networks in hostile environments has been mostly overlooked. Most of the existing localization protocols for sensor networks are vulnerable in hostile environments. The security of location discovery can certainly be enhanced by authentication. However, the possible node compromises and the fact that location determination uses certain physical features (e.g., received signal strength) of radio signals make authentication not as effective as in traditional security applications. This paper presents two methods to tolerate malicious attacks against beacon-based location discovery in sensor networks. The first method filters out malicious beacon signals on the basis of the “consistency ” among multiple beacon signals, while the second method tolerates malicious beacon signals by adopting an iteratively refined voting scheme. Both methods can survive malicious attacks even if the attacks bypass authentication, provided that the benign beacon signals constitute the majority of the beacon signals. This paper also presents the implementation of these techniques on MICA2 motes running TinyOS, and the evaluation through both simulation and field experiments. The experimental results demonstrate that the proposed methods are promising for the current generation of sensor networks. Categories and Subject Descriptors: C.2.0 [Computer-Communication Networks]: General—Security and protection

Attack-resistant location estimation in wireless sensor networks

Many sensor network applications require sensors ’ locations to function correctly. Despite the recent advances, location discovery for sensor networks in hostile environments has been mostly overlooked. Most of the existing localization protocols for sensor networks are vulnerable in hostile environments. The security of location discovery can certainly be enhanced by authentication. However, the possible node compromises and the fact that location determination uses certain physical features (e.g., received signal strength) of radio signals make authentication not as effective as in traditional security applications. This paper presents two methods to tolerate malicious attacks against range-based location discovery in sensor networks. The first method filters out malicious beacon signals on the basis of the “consistency ” among multiple beacon signals, while the second method tolerates malicious beacon signals by adopting an iteratively refined voting scheme. Both methods can survive malicious attacks even if the attacks bypass authentication, provided that the benign beacon signals constitute the majority of the beacon signals. This paper also presents the implementation and experimental evaluation (through both field experiments and simulation) of all the secure and resilient location estimation schemes that can be used on the current generation of sensor platforms (e.g., MICA series of motes), including the technique

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field