\u3cem\u3eIn vivo\u3c/em\u3e Dark-field Imaging of the Retinal Pigment Epithelium Cell Mosaic

Non-invasive reflectance imaging of the human RPE cell mosaic is demonstrated using a modified confocal adaptive optics scanning light ophthalmoscope (AOSLO). The confocal circular aperture in front of the imaging detector was replaced with a combination of a circular aperture 4 to 16 Airy disks in diameter and an opaque filament, 1 or 3 Airy disks thick. This arrangement reveals the RPE cell mosaic by dramatically attenuating the light backscattered by the photoreceptors. The RPE cell mosaic was visualized in all 7 recruited subjects at multiple retinal locations with varying degrees of contrast and cross-talk from the photoreceptors. Various experimental settings were explored for improving the visualization of the RPE cell boundaries including: pinhole diameter, filament thickness, illumination and imaging pupil apodization, unmatched imaging and illumination focus, wavelength and polarization. None of these offered an obvious path for enhancing image contrast. The demonstrated implementation of dark-field AOSLO imaging using 790 nm light requires low light exposures relative to light safety standards and it is more comfortable for the subject than the traditional autofluorescence RPE imaging with visible light. Both these factors make RPE dark-field imaging appealing for studying mechanisms of eye disease, as well as a clinical tool for screening and monitoring disease progression

Surgical technique for arthroscopic onlay suprapectoral biceps tenodesis with an all-suture anchor.

The long head of the biceps is a frequent pain generator in the shoulder. Tendinopathy of the long head of the biceps may be treated with biceps tenodesis. There has been great debate about the optimal technique for biceps tenodesis, without a clear distinction between different techniques. Biceps tenodesis fixation may include interference fixation, suspensory fixation, all-suture anchors, and soft tissue fixation. In this technical note, we describe an all-arthroscopic onlay suprapectoral biceps tenodesis with an all-suture anchor

Youth and the future: effective youth services for the year 2015

This report provides an understanding of the services required by young people in the year 2015, based on a thorough analysis of recent trends and expert projections of those trends. The report analyses key social and economic changes for young people in Australia over the past 10 to 20 years including movements in population, education, employment/unemployment and the labour market, incomes, family and household structure, health, and crime and justice

Not Quite Filling The Gap: Why the Miscellaneous Expense Allowance Leaves the NCAA Vulnerable to Antitrust Litigation

Throughout its history, the National Collegiate Athletic Association (NCAA) has been repeatedly accused of violating antitrust law in a range of different ways—restricting television broadcasts, limiting coaches’ salaries, and capping the amount of athletic scholarships. Most recently, in the case of White v. NCAA, a class of plaintiffs argued that the NCAA’s artificial limitation on student-athlete compensation violated antitrust law. Although this case settled before trial, it represented a major victory for student-athletes. The NCAA is now considering a proposal— the Miscellaneous Expense Allowance (“MEA”)—that would raise the NCAA’s artificial cap on athletics-related financial aid by $2000. This legislation is partially aimed at protecting the NCAA from further antitrust liability, but it does not quite fill the gap. After providing a brief history of college athletics and student-athlete compensation, this Note then examines the mechanics of antitrust law and how courts have applied antitrust law in the context of the NCAA. This Note then argues that a hypothetical class of student-athletes could still bring a viable antitrust claim against the NCAA, even if the MEA is passed. Subsequently, this Note analyzes the arguments on both sides that would arise in such a hypothetical lawsuit

Disentangling the spatial substructure of Cygnus OB2 from Gaia DR2

© 2019 The Author(s) Published by Oxford University Press on behalf of the Royal Astronomical SocietyFor the first time, we have explored the spatial substructure of the Cygnus OB2 association using parallaxes from the recent second Gaia data release. We find significant line-of-sight substructure within the association, which we quantify using a parametrized model that reproduces the observed parallax distribution. This inference approach is necessary due to the non-linearity of the parallax distance transformation and the asymmetry of the resulting probability distribution. Using a Markov Chain Monte Carlo ensemble sampler and an unbinned maximum likelihood test, we identify two different stellar groups superposed on the association. We find the main Cygnus OB2 group at ∼1760 pc, further away than recent estimates have envisaged, and a foreground group at ∼1350 pc. We also calculate individual membership probabilities and identify outliers as possible non-members of the association.Peer reviewe